Detailed information NTG0676370

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: MRK42_RS19240
• Genome accession: NZ_CP095328
• Coordinates: 4192465..4193706 (+)
• Length: 413 a.a.
• NCBI ID: WP_026456598.1
• Uniprot ID: -
• Organism: Aeromonas sp. 19NY04SH05-1
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4187465..4198706

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MRK42_RS19215 (MRK42_19160)	ampD	4187810..4188391 (-)	582	WP_354688546.1	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	-
MRK42_RS19220 (MRK42_19165)	-	4188415..4188885 (+)	471	WP_354688547.1	retropepsin-like aspartic protease	-
MRK42_RS19225 (MRK42_19170)	nadC	4188889..4189746 (+)	858	WP_354688548.1	carboxylating nicotinate-nucleotide diphosphorylase	-
MRK42_RS19230 (MRK42_19175)	-	4190121..4190531 (+)	411	WP_354688549.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
MRK42_RS19235 (MRK42_19180)	pilB	4190535..4192241 (+)	1707	WP_354688550.1	PilB family type IVa pilus assembly ATPase TapB	Machinery gene
MRK42_RS19240 (MRK42_19185)	pilC	4192465..4193706 (+)	1242	WP_026456598.1	type II secretion system F family protein	Machinery gene
MRK42_RS19245 (MRK42_19190)	pilD	4193773..4194648 (+)	876	WP_342013424.1	A24 family peptidase	Machinery gene
MRK42_RS19250 (MRK42_19195)	coaE	4194652..4195266 (+)	615	WP_354688551.1	dephospho-CoA kinase	-
MRK42_RS19255 (MRK42_19200)	zapD	4195304..4196026 (+)	723	WP_354688552.1	cell division protein ZapD	-
MRK42_RS19260 (MRK42_19205)	yacG	4196036..4196230 (+)	195	WP_026457308.1	DNA gyrase inhibitor YacG	-
MRK42_RS19265 (MRK42_19210)	mutT	4196293..4196688 (-)	396	WP_026457309.1	8-oxo-dGTP diphosphatase MutT	-

Sequence

Protein

• Length: 413 a.a.
• Molecular weight: 45329.45 Da
• Isoelectric Point: 9.8389

>NTDB_id=676370 MRK42_RS19240 WP_026456598.1 4192465..4193706(+) (pilC) [Aeromonas sp. 19NY04SH05-1]
MATLTNKNNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGIVAADVETGTPMSEALRRHPRYFDALYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVFFGGAA
LAIFLYVRAWRASQKVRDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide

• Length: 1242 bp

>NTDB_id=676370 MRK42_RS19240 WP_026456598.1 4192465..4193706(+) (pilC) [Aeromonas sp. 19NY04SH05-1]
ATGGCAACGCTAACCAACAAAAATAATGCCCCCAAGAAAGTCTTCGCGTTTCGCTGGAGCGGGGTCAACCGCAAGGGCCA
GAAAGTCTCTGGTGAACTCCAGGCCGACAGCATCAATACCGTCAAGGCCGAGCTGCGCAAGCAGGGGGTCAATGTCACCA
AGGTGGCCAAGAAATCCCAGGGGTTGTTCTCCAAAGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCGCGC
CAGATCACCACCATGCTCTCCGCCGGTGTACCGCTGGTGCAGAGCTTGCAGATCATCGCCCGCAGCCATGAAAAAGCCTC
GATGCGCGAGCTGATGGGGATCGTCGCCGCCGATGTGGAGACCGGCACCCCCATGTCGGAAGCGCTGCGCCGCCATCCCC
GCTACTTTGATGCCCTCTACTGCGATCTGGTGGAGGCGGGCGAGCAGTCCGGCGCGCTGGAGACCATCTATGATCGCATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAGTCCAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTGTTCGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGCGCCGAGC
TGCCCATCTTCACCCAGTTCGTCATCGGCATCTCCCGCTTCATGCAGAACTGGTGGTATGTCTTCTTCGGCGGGGCGGCG
CTCGCCATCTTCCTCTACGTCCGCGCCTGGCGCGCTTCTCAAAAGGTAAGAGACAACACCGACAAGTTTGTGCTGACCAT
CCCGGTGGTCGGCATGATACTGCACAAGGCGGCCATGGCCCGCTTTGCCCGCACCCTCTCGACCACCTTCTCGGCCGGTA
TCCCATTGGTGGATGCCCTCATCTCGGCGGCGGGGGCCTCCGGCAACTATGTCTATCGCACTGCCGTCATGGCCATTCGC
AACGAGGTGGTAGCGGGCATGCAAATCAACGTGGCGATGCGCACCGTGGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCCGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTGGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTGATCGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGATGTCGTGGGTTGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (282-404)

• Type II secretion system (T2SS), protein F (T2SSF) (79-201)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Pseudomonas stutzeri DSM 10701	57.828	95.884	0.554
pilC	Acinetobacter baumannii D1279779	53.75	96.852	0.521
pilC	Acinetobacter baylyi ADP1	53.634	96.61	0.518
pilC	Legionella pneumophila strain ERS1305867	50.614	98.547	0.499
pilC	Vibrio cholerae strain A1552	47.118	96.61	0.455
pilC	Vibrio campbellii strain DS40M4	46.734	96.368	0.45
pilG	Neisseria gonorrhoeae MS11	40.247	98.063	0.395
pilG	Neisseria meningitidis 44/76-A	40	98.063	0.392
pilC	Thermus thermophilus HB27	38.5	96.852	0.373