Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   MUY23_RS00250 Genome accession   NZ_CP095162
Coordinates   48439..49389 (+) Length   316 a.a.
NCBI ID   WP_002936562.1    Uniprot ID   A0A142UQX7
Organism   Streptococcus suis strain TJS75     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 43439..54389
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUY23_RS00240 - 47003..47368 (+) 366 WP_002936568.1 DUF1033 family protein -
  MUY23_RS00245 - 47403..48353 (-) 951 WP_002936565.1 S66 peptidase family protein -
  MUY23_RS00250 comYA 48439..49389 (+) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  MUY23_RS00255 comYB 49301..50173 (+) 873 WP_053866392.1 type II secretion system F family protein Machinery gene
  MUY23_RS00260 comYC 50175..50456 (+) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  MUY23_RS00265 comGD 50437..50745 (+) 309 WP_002936549.1 competence type IV pilus minor pilin ComGD -
  MUY23_RS00270 comYE 50829..51122 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  MUY23_RS00275 comGF/cglF 51109..51543 (+) 435 WP_002936547.1 competence type IV pilus minor pilin ComGF Machinery gene
  MUY23_RS00280 comGG 51521..51931 (+) 411 WP_002936546.1 competence type IV pilus minor pilin ComGG -
  MUY23_RS00285 comYH 51988..52941 (+) 954 WP_002936545.1 class I SAM-dependent methyltransferase Machinery gene
  MUY23_RS00290 - 52991..54178 (+) 1188 WP_002936543.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35490.39 Da        Isoelectric Point: 6.1802

>NTDB_id=675814 MUY23_RS00250 WP_002936562.1 48439..49389(+) (comYA) [Streptococcus suis strain TJS75]
MIQEKARKLIEKAVADRVSDIYLVPRGESYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIRGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=675814 MUY23_RS00250 WP_002936562.1 48439..49389(+) (comYA) [Streptococcus suis strain TJS75]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAAAGGCAGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGCGG
GGAAAGCTATCAAGTTTATCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTCTGGTGATCCGCTTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCTGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACCG
CTCGAGCAGTCATTCGAGCCAGTCTGACAGGAGCGACGGTCTTCTCAACGGTTCACGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGTCCTGAGGAGTTAAACAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCAG
GGGAGGAGGTGTGGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A142UQX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.387

98.101

0.671
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.952

98.418

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364