Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   MUY23_RS00255 Genome accession   NZ_CP095162
Coordinates   49301..50173 (+) Length   290 a.a.
NCBI ID   WP_053866392.1    Uniprot ID   -
Organism   Streptococcus suis strain TJS75     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 44301..55173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MUY23_RS00240 - 47003..47368 (+) 366 WP_002936568.1 DUF1033 family protein -
  MUY23_RS00245 - 47403..48353 (-) 951 WP_002936565.1 S66 peptidase family protein -
  MUY23_RS00250 comYA 48439..49389 (+) 951 WP_002936562.1 competence type IV pilus ATPase ComGA Machinery gene
  MUY23_RS00255 comYB 49301..50173 (+) 873 WP_053866392.1 type II secretion system F family protein Machinery gene
  MUY23_RS00260 comYC 50175..50456 (+) 282 WP_002936550.1 competence type IV pilus major pilin ComGC Machinery gene
  MUY23_RS00265 comGD 50437..50745 (+) 309 WP_002936549.1 competence type IV pilus minor pilin ComGD -
  MUY23_RS00270 comYE 50829..51122 (+) 294 WP_002936548.1 competence type IV pilus minor pilin ComGE Machinery gene
  MUY23_RS00275 comGF/cglF 51109..51543 (+) 435 WP_002936547.1 competence type IV pilus minor pilin ComGF Machinery gene
  MUY23_RS00280 comGG 51521..51931 (+) 411 WP_002936546.1 competence type IV pilus minor pilin ComGG -
  MUY23_RS00285 comYH 51988..52941 (+) 954 WP_002936545.1 class I SAM-dependent methyltransferase Machinery gene
  MUY23_RS00290 - 52991..54178 (+) 1188 WP_002936543.1 acetate kinase -
  MUY23_RS00295 - 54493..55044 (+) 552 WP_014636756.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 32726.02 Da        Isoelectric Point: 9.8896

>NTDB_id=675815 MUY23_RS00255 WP_053866392.1 49301..50173(+) (comYB) [Streptococcus suis strain TJS75]
MRKLIAFLQQDISVLGRQKQKKLPLVRQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADLYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLFLIMLGLKNYLLPQLEEGNAATM
LINHLPTIFLSLCGLSLVAVLAGMVWFRKTNKIKAFSRLAALPFFGKLIQIYLTAYYAREWGSLIVEYGQVKSKLGGELT
VYAAECWEDFFSRVNRAMQLIQPLVFLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 873 bp        

>NTDB_id=675815 MUY23_RS00255 WP_053866392.1 49301..50173(+) (comYB) [Streptococcus suis strain TJS75]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTAGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCTCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTACTG
GCAGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TGGGTTTTCTGTTCTTGATTATGCTAGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCTGCGACCATG
CTAATTAACCATCTGCCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTGGCTGGTATGGTTTGGTT
TCGCAAAACCAACAAAATCAAGGCATTTTCCCGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAATCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGAAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGTTGACA
GTTTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGTTGATTCAACCGCTGGTCTTTCT
CTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(222-283)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

53.216

100

0.628
  comYB Streptococcus mutans UA140

49.56

100

0.583
  comYB Streptococcus mutans UA159

49.56

100

0.583
  comGB/cglB Streptococcus mitis NCTC 12261

49.254

100

0.569
  comGB/cglB Streptococcus mitis SK321

49.107

100

0.569
  comGB/cglB Streptococcus pneumoniae Rx1

48.955

100

0.566
  comGB/cglB Streptococcus pneumoniae D39

48.955

100

0.566
  comGB/cglB Streptococcus pneumoniae R6

48.955

100

0.566
  comGB/cglB Streptococcus pneumoniae TIGR4

48.955

100

0.566
  comGB Lactococcus lactis subsp. cremoris KW2

44.214

100

0.514