Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   MP619_RS00785 Genome accession   NZ_CP095081
Coordinates   132197..133138 (+) Length   313 a.a.
NCBI ID   WP_129555184.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 127197..138138
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS00775 (MP619_00770) rpoC 127906..131547 (+) 3642 WP_111714766.1 DNA-directed RNA polymerase subunit beta' -
  MP619_RS00780 (MP619_00775) - 131751..132116 (+) 366 WP_129555183.1 DUF1033 family protein -
  MP619_RS00785 (MP619_00780) comYA 132197..133138 (+) 942 WP_129555184.1 competence type IV pilus ATPase ComGA Machinery gene
  MP619_RS00790 (MP619_00785) comYB 133074..134105 (+) 1032 WP_129556365.1 competence type IV pilus assembly protein ComGB Machinery gene
  MP619_RS00795 (MP619_00790) comYC 134107..134433 (+) 327 WP_111714771.1 competence type IV pilus major pilin ComGC Machinery gene
  MP619_RS00800 (MP619_00795) - 134463..135923 (-) 1461 WP_155783027.1 recombinase family protein -
  MP619_RS00805 (MP619_00800) - 136200..136655 (-) 456 WP_155778381.1 Ltp family lipoprotein -
  MP619_RS00810 (MP619_00805) - 136704..137465 (-) 762 WP_268227792.1 S24 family peptidase -
  MP619_RS00815 (MP619_00810) - 137627..137830 (+) 204 WP_155778382.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35248.39 Da        Isoelectric Point: 7.0192

>NTDB_id=675072 MP619_RS00785 WP_129555184.1 132197..133138(+) (comYA) [Streptococcus dysgalactiae strain WJ001]
MVQALARSILKEAEQMQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IGEDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMYQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARLEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=675072 MP619_RS00785 WP_129555184.1 132197..133138(+) (comYA) [Streptococcus dysgalactiae strain WJ001]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATGCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGGTGAAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACACTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCTGGTCCAGTCGGATCAGGCAAAACGACTTTGATGTACCAATTGATTGCTGATTATTATCAGGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAGGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGTATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCAGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

62.058

99.361

0.617
  comYA Streptococcus mutans UA159

62.058

99.361

0.617
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.258

99.042

0.617
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.361

0.604
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.361

0.594
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.486

99.361

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

52.09

99.361

0.518
  comGA Latilactobacillus sakei subsp. sakei 23K

39.249

93.61

0.367