Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   MP619_RS00790 Genome accession   NZ_CP095081
Coordinates   133074..134105 (+) Length   343 a.a.
NCBI ID   WP_129556365.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 128074..139105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS00780 (MP619_00775) - 131751..132116 (+) 366 WP_129555183.1 DUF1033 family protein -
  MP619_RS00785 (MP619_00780) comYA 132197..133138 (+) 942 WP_129555184.1 competence type IV pilus ATPase ComGA Machinery gene
  MP619_RS00790 (MP619_00785) comYB 133074..134105 (+) 1032 WP_129556365.1 competence type IV pilus assembly protein ComGB Machinery gene
  MP619_RS00795 (MP619_00790) comYC 134107..134433 (+) 327 WP_111714771.1 competence type IV pilus major pilin ComGC Machinery gene
  MP619_RS00800 (MP619_00795) - 134463..135923 (-) 1461 WP_155783027.1 recombinase family protein -
  MP619_RS00805 (MP619_00800) - 136200..136655 (-) 456 WP_155778381.1 Ltp family lipoprotein -
  MP619_RS00810 (MP619_00805) - 136704..137465 (-) 762 WP_268227792.1 S24 family peptidase -
  MP619_RS00815 (MP619_00810) - 137627..137830 (+) 204 WP_155778382.1 helix-turn-helix transcriptional regulator -
  MP619_RS00820 (MP619_00815) - 137993..138253 (-) 261 WP_155778383.1 hypothetical protein -
  MP619_RS00825 (MP619_00820) - 138377..138547 (+) 171 WP_268227793.1 hypothetical protein -
  MP619_RS00830 (MP619_00825) - 138526..138672 (+) 147 WP_196772223.1 hypothetical protein -
  MP619_RS00835 (MP619_00830) - 138715..139050 (+) 336 WP_155783026.1 transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 38937.35 Da        Isoelectric Point: 8.9053

>NTDB_id=675073 MP619_RS00790 WP_129556365.1 133074..134105(+) (comYB) [Streptococcus dysgalactiae strain WJ001]
MTFLQQDISVRSKQGLKKLSSKEQYKLIQLLANLLLTGFNLTEIIAFLTKSHLIPEPYVLRMEEVLLKGRGLADMLAGIG
FSDAILTQISLADGHGNIETTLVNIQGYLNQMAKLKRKTIEVVTYPIILLVFLFVMMLGLRHYVMPQLEAQNQLTIFLTH
FPAIFFGLILFIGVLLGGIWLHWRSQSRLKLFTHLSAYPVLGKLLQQYLTAYYAREWGTLIGQGLELPVILDIMAMEKSL
FMQELAEDIRVSLLAGQAFHDKVATYPFFKKELSLMITYGEIKSKLGSELEIYAQESWAQFFSQLHQATQFIQPIIFLVI
ALTIVMIYAAILLPIYQNMGGVL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=675073 MP619_RS00790 WP_129556365.1 133074..134105(+) (comYB) [Streptococcus dysgalactiae strain WJ001]
ATGACCTTCTTGCAGCAGGACATCTCAGTCCGGAGCAAGCAAGGCTTGAAAAAATTATCCAGTAAGGAACAATACAAACT
AATTCAGCTATTAGCTAACCTTTTGTTAACAGGATTTAACTTGACTGAGATAATAGCTTTCTTAACAAAAAGTCATTTGA
TTCCCGAGCCCTATGTTCTTCGCATGGAAGAAGTACTCTTAAAAGGTCGAGGGCTGGCAGATATGTTAGCTGGGATAGGT
TTTTCGGATGCTATTTTAACTCAAATTAGTTTAGCAGATGGTCACGGAAACATTGAGACGACGCTTGTTAATATTCAGGG
CTATCTCAACCAAATGGCTAAACTTAAACGAAAAACCATTGAAGTCGTCACCTATCCGATTATTCTCCTGGTATTTCTTT
TTGTGATGATGTTAGGGTTAAGGCATTATGTTATGCCTCAATTAGAAGCTCAAAATCAGCTTACTATTTTTCTCACTCAT
TTTCCAGCTATTTTCTTTGGTCTTATCCTTTTTATAGGTGTGCTGTTAGGGGGAATTTGGCTGCATTGGCGATCGCAAAG
TCGCCTCAAGCTTTTTACTCACCTCAGTGCTTATCCTGTTTTAGGGAAACTCTTACAACAGTATCTGACGGCTTATTATG
CTAGAGAATGGGGAACATTGATTGGACAGGGACTTGAATTACCAGTCATTCTGGATATTATGGCCATGGAGAAATCTTTA
TTCATGCAAGAATTGGCTGAAGATATTCGAGTTAGTTTATTGGCAGGACAAGCTTTTCATGATAAGGTAGCTACCTATCC
TTTCTTCAAAAAAGAGTTAAGTTTGATGATTACTTATGGAGAGATTAAATCCAAATTAGGAAGTGAACTAGAGATTTATG
CTCAAGAGAGTTGGGCTCAGTTTTTCAGCCAACTTCATCAAGCAACTCAGTTTATTCAACCGATTATCTTTTTAGTGATT
GCTCTGACGATTGTCATGATTTATGCAGCAATTTTATTACCAATTTATCAAAATATGGGAGGCGTTTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.277

98.834

0.536
  comYB Streptococcus mutans UA159

54.277

98.834

0.536
  comYB Streptococcus gordonii str. Challis substr. CH1

49.263

98.834

0.487
  comGB/cglB Streptococcus mitis NCTC 12261

46.567

97.668

0.455
  comGB/cglB Streptococcus mitis SK321

45.946

97.085

0.446
  comGB/cglB Streptococcus pneumoniae Rx1

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae D39

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae R6

44.444

97.085

0.431
  comGB/cglB Streptococcus pneumoniae TIGR4

44.444

97.085

0.431
  comGB Lactococcus lactis subsp. cremoris KW2

43.363

98.834

0.429