Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   SVA_RS03480 Genome accession   NZ_AP014936
Coordinates   703621..704847 (-) Length   408 a.a.
NCBI ID   WP_096458870.1    Uniprot ID   A0A1B4V1C0
Organism   Sulfurifustis variabilis strain skN76     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 698621..709847
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SVA_RS03460 (SVA_0705) argJ 699866..701083 (+) 1218 WP_096458858.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
  SVA_RS03465 (SVA_0706) - 701093..702085 (+) 993 WP_096458861.1 Nudix family hydrolase -
  SVA_RS03470 (SVA_0707) coaE 702082..702684 (-) 603 WP_096458864.1 dephospho-CoA kinase -
  SVA_RS03475 (SVA_0708) pilD 702708..703565 (-) 858 WP_096458867.1 prepilin peptidase Machinery gene
  SVA_RS03480 (SVA_0709) pilC 703621..704847 (-) 1227 WP_096458870.1 type II secretion system F family protein Machinery gene
  SVA_RS03485 (SVA_0710) pilB 704847..706565 (-) 1719 WP_096458873.1 type IV-A pilus assembly ATPase PilB Machinery gene
  SVA_RS03490 (SVA_0711) - 706962..707384 (+) 423 WP_096458877.1 rubrerythrin family protein -
  SVA_RS03495 (SVA_0712) - 707454..708818 (+) 1365 WP_096458880.1 heterodisulfide reductase-related iron-sulfur binding cluster -
  SVA_RS03500 (SVA_0713) - 708815..709429 (+) 615 WP_197703352.1 DUF3501 family protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44193.03 Da        Isoelectric Point: 9.8235

>NTDB_id=67421 SVA_RS03480 WP_096458870.1 703621..704847(-) (pilC) [Sulfurifustis variabilis strain skN76]
MAVAAKKPQFDAYSWEGVDKQGKKVRGEMEAASVAFVNATLRRQGINPVKVAKRRKSLGSLKKKKIKPKDIAIFTRQLAT
MLQAGIPIAQSFEIVGKGHENPSMQELILGIKNDIESGTNLTAALSKHPLYFDALYCNLVAAGEQAGILDNILDKVATYK
EKIEAIKGKIKSALFYPTAVVVVAFIITAILLMFVIPQFEDLFKGFGADLPALTQFVIGLSRAFRDSWYLIFGTIIGTIV
TVGYTYRRSPKMQHAVDRLTLKAPIVGEIIKKATIARFSRTLATMFAAGVPLVEALESVAGAAGNRIYYEGTQAIRADVS
TGMQLQAAMNATGLFPNMVVQMVAIGEESGELDTMLGKVADFYEREVDDAVAALSSLLEPIIMAFLGVVIGGLVVAMYLP
IFKMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=67421 SVA_RS03480 WP_096458870.1 703621..704847(-) (pilC) [Sulfurifustis variabilis strain skN76]
ATGGCCGTCGCCGCAAAAAAGCCCCAGTTCGACGCCTATTCCTGGGAAGGCGTCGACAAGCAGGGCAAAAAAGTCAGGGG
CGAGATGGAGGCGGCCAGCGTCGCGTTCGTCAACGCCACCCTTCGGCGACAGGGCATCAATCCCGTCAAGGTGGCGAAGC
GCCGCAAGTCGCTCGGGTCGCTCAAAAAAAAGAAGATCAAACCAAAAGACATCGCCATCTTCACGCGCCAGCTCGCGACG
ATGTTGCAGGCCGGCATTCCGATCGCGCAGTCCTTCGAGATCGTGGGCAAGGGCCACGAAAACCCCTCTATGCAGGAGCT
GATTCTCGGCATCAAGAACGACATCGAGTCCGGCACCAACCTCACGGCCGCCCTTTCCAAGCACCCGCTCTATTTCGACG
CGCTCTACTGCAACCTGGTCGCCGCCGGGGAGCAGGCCGGCATCCTGGACAACATCCTCGACAAGGTCGCGACCTACAAG
GAAAAGATCGAGGCGATCAAGGGAAAGATCAAATCCGCGCTCTTTTATCCGACCGCCGTCGTCGTCGTCGCGTTCATCAT
CACCGCGATCCTCCTGATGTTCGTCATTCCCCAGTTCGAGGATCTGTTCAAGGGCTTTGGGGCGGATTTGCCGGCGCTGA
CCCAGTTCGTCATAGGTCTTTCGCGCGCGTTCCGCGACAGCTGGTATCTCATATTCGGCACGATTATCGGCACGATCGTC
ACGGTCGGATACACCTACAGACGCTCTCCCAAAATGCAGCATGCGGTCGATCGTCTGACCCTCAAAGCGCCGATTGTCGG
TGAGATCATCAAGAAGGCCACGATTGCCCGCTTTTCGCGTACGCTCGCCACAATGTTCGCCGCCGGCGTCCCTCTGGTGG
AAGCGCTCGAGTCGGTCGCCGGCGCAGCGGGCAACCGTATCTATTACGAGGGCACGCAAGCGATACGGGCGGACGTCAGC
ACAGGCATGCAGTTGCAGGCGGCGATGAACGCGACCGGACTCTTCCCGAACATGGTGGTGCAGATGGTTGCGATCGGCGA
GGAATCCGGTGAGCTGGACACGATGCTCGGCAAAGTCGCCGACTTTTACGAGCGGGAGGTCGATGACGCGGTTGCCGCAC
TCTCCAGCCTGCTTGAGCCCATCATCATGGCGTTCCTCGGCGTGGTTATCGGCGGCCTGGTCGTAGCAATGTACCTGCCC
ATCTTCAAAATGGGCTCGGTCGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1B4V1C0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

58.105

98.284

0.571
  pilC Pseudomonas stutzeri DSM 10701

55.911

99.51

0.556
  pilC Acinetobacter baylyi ADP1

53.431

100

0.534
  pilC Acinetobacter baumannii D1279779

53.186

100

0.532
  pilG Neisseria meningitidis 44/76-A

48.601

96.324

0.468
  pilG Neisseria gonorrhoeae MS11

48.705

94.608

0.461
  pilC Vibrio cholerae strain A1552

44.472

97.549

0.434
  pilC Vibrio campbellii strain DS40M4

42.289

98.529

0.417
  pilC Thermus thermophilus HB27

39.9

98.284

0.392

Multiple sequence alignment