Detailed information NTG0671102

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: MUA26_RS05440
• Genome accession: NZ_CP094717
• Coordinates: 1116429..1116797 (+)
• Length: 122 a.a.
• NCBI ID: WP_262613672.1
• Uniprot ID: -
• Organism: Staphylococcus sp. IVB6246
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1111429..1121797

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA26_RS05400 (MUA26_05380)	yqeH	1111635..1112735 (+)	1101	WP_262613670.1	ribosome biogenesis GTPase YqeH	-
MUA26_RS05405 (MUA26_05385)	aroE	1112748..1113554 (+)	807	WP_262603198.1	shikimate dehydrogenase	-
MUA26_RS05410 (MUA26_05390)	yhbY	1113574..1113867 (+)	294	WP_262603199.1	ribosome assembly RNA-binding protein YhbY	-
MUA26_RS05415 (MUA26_05395)	nadD	1113867..1114433 (+)	567	WP_262603200.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
MUA26_RS05420 (MUA26_05400)	yqeK	1114426..1114998 (+)	573	WP_262603201.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
MUA26_RS05425 (MUA26_05405)	rsfS	1115010..1115366 (+)	357	WP_262603202.1	ribosome silencing factor	-
MUA26_RS05430 (MUA26_05410)	-	1115366..1116088 (+)	723	WP_262603203.1	class I SAM-dependent methyltransferase	-
MUA26_RS05435 (MUA26_05415)	-	1116145..1116432 (+)	288	WP_262613671.1	hypothetical protein	-
MUA26_RS05440 (MUA26_05420)	comEA	1116429..1116797 (+)	369	WP_262613672.1	helix-hairpin-helix domain-containing protein	Machinery gene
MUA26_RS05445 (MUA26_05425)	-	1116863..1117327 (+)	465	WP_262603205.1	ComE operon protein 2	-
MUA26_RS05450 (MUA26_05430)	-	1117501..1119558 (+)	2058	WP_262613673.1	DNA internalization-related competence protein ComEC/Rec2	-
MUA26_RS05455 (MUA26_05435)	holA	1119621..1120595 (+)	975	WP_262603207.1	DNA polymerase III subunit delta	-
MUA26_RS05460 (MUA26_05440)	rpsT	1120725..1120973 (-)	249	WP_095116721.1	30S ribosomal protein S20	-

Sequence

Protein

• Length: 122 a.a.
• Molecular weight: 13187.88 Da
• Isoelectric Point: 4.8146

>NTDB_id=671102 MUA26_RS05440 WP_262613672.1 1116429..1116797(+) (comEA) [Staphylococcus sp. IVB6246]
MKQLIDKAGVLPNADLTKINLAEKLTDQKMIYIPQKGEQVDPSLSAGPNNSNGASPGQNQVINLNTAQLNDLTNVPGIGP
AKAQAILAYREEKGQFQSVEELKEVKGIGDKTYENLSSYFTV

Nucleotide

• Length: 369 bp

>NTDB_id=671102 MUA26_RS05440 WP_262613672.1 1116429..1116797(+) (comEA) [Staphylococcus sp. IVB6246]
ATGAAGCAATTGATTGATAAAGCAGGGGTTTTACCTAATGCTGACTTAACAAAAATTAATCTTGCTGAAAAGTTGACGGA
TCAAAAGATGATCTATATCCCACAAAAAGGAGAACAGGTTGATCCATCATTATCTGCTGGGCCCAATAATTCAAATGGAG
CTAGCCCAGGGCAAAATCAGGTCATTAATTTGAATACAGCACAACTCAATGATTTAACGAATGTTCCGGGAATAGGACCT
GCGAAAGCACAAGCGATATTAGCTTATCGAGAGGAAAAGGGTCAATTTCAGTCTGTTGAAGAATTGAAAGAAGTGAAAGG
TATTGGAGATAAAACATATGAAAACTTAAGCAGTTATTTTACGGTTTGA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (59-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Staphylococcus aureus N315	50.413	99.18	0.5
comEA	Staphylococcus aureus MW2	50.413	99.18	0.5
comEA	Latilactobacillus sakei subsp. sakei 23K	41.732	100	0.434
comEA	Bacillus subtilis subsp. subtilis str. 168	43.089	100	0.434
comEA/celA/cilE	Streptococcus mitis SK321	43.966	95.082	0.418
comEA/celA/cilE	Streptococcus mitis NCTC 12261	43.86	93.443	0.41
comEA/celA/cilE	Streptococcus pneumoniae R6	41.228	93.443	0.385
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.228	93.443	0.385
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	41.228	93.443	0.385
comEA/celA/cilE	Streptococcus pneumoniae D39	41.228	93.443	0.385
comEA	Lactococcus lactis subsp. cremoris KW2	38.211	100	0.385
comEA	Streptococcus thermophilus LMD-9	39.64	90.984	0.361