Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   MP387_RS00830 Genome accession   NZ_CP094226
Coordinates   164371..165387 (+) Length   338 a.a.
NCBI ID   WP_242748017.1    Uniprot ID   -
Organism   Streptococcus oralis strain 1648     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 159371..170387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP387_RS00810 (MP387_00810) - 159791..161608 (+) 1818 WP_242746929.1 acyltransferase family protein -
  MP387_RS00815 (MP387_00815) nagA 161749..162900 (+) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -
  MP387_RS00820 (MP387_00820) - 163053..163418 (+) 366 WP_000286396.1 DUF1033 family protein -
  MP387_RS00825 (MP387_00825) comGA/cglA/cilD 163482..164423 (+) 942 WP_242746934.1 competence type IV pilus ATPase ComGA Machinery gene
  MP387_RS00830 (MP387_00830) comGB/cglB 164371..165387 (+) 1017 WP_242748017.1 competence type IV pilus assembly protein ComGB Machinery gene
  MP387_RS00835 (MP387_00835) comGC/cglC 165389..165712 (+) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  MP387_RS00840 (MP387_00840) comGD/cglD 165675..166109 (+) 435 WP_242746960.1 competence type IV pilus minor pilin ComGD Machinery gene
  MP387_RS00845 (MP387_00845) comGE/cglE 166072..166374 (+) 303 WP_242746963.1 competence type IV pilus minor pilin ComGE Machinery gene
  MP387_RS00850 (MP387_00850) comGF/cglF 166337..166798 (+) 462 WP_242746966.1 competence type IV pilus minor pilin ComGF Machinery gene
  MP387_RS00855 (MP387_00855) comGG/cglG 166776..167189 (+) 414 WP_242746969.1 competence type IV pilus minor pilin ComGG Machinery gene
  MP387_RS00860 (MP387_00860) - 167222..167812 (+) 591 WP_242746972.1 class I SAM-dependent methyltransferase -
  MP387_RS00865 (MP387_00865) comYH 167871..168824 (+) 954 WP_242746975.1 class I SAM-dependent methyltransferase Machinery gene
  MP387_RS00870 (MP387_00870) - 168875..170065 (+) 1191 WP_242746978.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38509.60 Da        Isoelectric Point: 9.5635

>NTDB_id=668075 MP387_RS00830 WP_242748017.1 164371..165387(+) (comGB/cglB) [Streptococcus oralis strain 1648]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLSHGKSFSEMMDSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=668075 MP387_RS00830 WP_242748017.1 164371..165387(+) (comGB/cglB) [Streptococcus oralis strain 1648]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATTACCTTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTCTTGGGCAGAAGTGCTTTGCTGGAAAAGGACTATG
TGGCCCAGATGCACCAAGGATTGTCTCATGGGAAATCTTTTTCAGAGATGATGGACAGCTTGGGTTTTTCAAGTGCTATT
GTGACCCAATTATCTCTAGCTGAAGTACATGGAAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGATAATTT
GGCCAAGGTCAAGAAAAAGTTAATCGAAGTGGCGACTTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGTTGG
GGCTCAGGAATTATTTGCTCCCCCAACTGGACAGTAGCAATATCGCCACCCAAATCATCGGCAATCTGCCACAAATATTT
CTGGGACTAGTGTTGGTTTGCTCTCTATCTTTGCTTTTAGCTCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTTTT
CTCGATGTTGGCACGGATTCCCTTTCTAGGAATCTTTGTCCAGACCTATCTGACGGCCTATTATGCGCGTGAATGGGGCA
ATATGATTTCACAGGGGATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGCTCCCAGCTCTTTAAAGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAGAAGGA
GTTGAGTCTCATCATCGAGTATGGAGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTTAATCGTACCATGAATCTGGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATTGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.787

100

0.938
  comGB/cglB Streptococcus mitis NCTC 12261

92.899

100

0.929
  comGB/cglB Streptococcus pneumoniae Rx1

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae D39

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae R6

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae TIGR4

91.124

100

0.911
  comYB Streptococcus gordonii str. Challis substr. CH1

73.81

99.408

0.734
  comYB Streptococcus mutans UA140

59.248

94.379

0.559
  comYB Streptococcus mutans UA159

59.248

94.379

0.559
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment