Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OIC43_RS33400 Genome accession   NZ_CP108876
Coordinates   7412198..7412842 (+) Length   214 a.a.
NCBI ID   WP_124718426.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00825     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7407198..7417842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OIC43_RS33390 (OIC43_33375) - 7409794..7410564 (-) 771 WP_266691631.1 transglycosylase SLT domain-containing protein -
  OIC43_RS33395 (OIC43_33380) - 7411060..7412205 (+) 1146 WP_266691633.1 GAF domain-containing sensor histidine kinase -
  OIC43_RS33400 (OIC43_33385) vraR 7412198..7412842 (+) 645 WP_124718426.1 response regulator transcription factor Regulator
  OIC43_RS33405 (OIC43_33390) - 7412988..7413236 (+) 249 WP_259931077.1 chaplin -
  OIC43_RS33410 (OIC43_33395) - 7413356..7414141 (-) 786 WP_266691635.1 hypothetical protein -
  OIC43_RS33415 (OIC43_33400) - 7414284..7415081 (+) 798 WP_124718429.1 ABC transporter ATP-binding protein -
  OIC43_RS33420 (OIC43_33405) - 7415172..7415600 (+) 429 WP_266691637.1 NfeD family protein -
  OIC43_RS33425 (OIC43_33410) - 7415747..7416676 (+) 930 WP_124718431.1 SPFH domain-containing protein -
  OIC43_RS33430 (OIC43_33415) - 7416738..7417505 (+) 768 WP_266691639.1 sulfite exporter TauE/SafE family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23111.38 Da        Isoelectric Point: 5.1683

>NTDB_id=668078 OIC43_RS33400 WP_124718426.1 7412198..7412842(+) (vraR) [Streptomyces sp. NBC_00825]
MADKIIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEAADGAEGVARTEELRPDVVLMDIKMPGTDGIEALRRLRELENPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVYAGHVLLQPEVAGALLAQEDSGSGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLSDRTQAALWAVRHGAAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=668078 OIC43_RS33400 WP_124718426.1 7412198..7412842(+) (vraR) [Streptomyces sp. NBC_00825]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCACCAGGTGGTCCGCCGCGGTCTGCGTACGTTCCTGGAGAT
CCAGGACGACATAGAGGTGGTAGGCGAGGCGGCCGACGGCGCCGAGGGGGTGGCCAGGACCGAGGAGCTCCGCCCCGACG
TCGTCCTGATGGACATCAAGATGCCCGGCACCGACGGCATCGAGGCGCTGCGCAGGCTGCGCGAACTGGAGAACCCGGCC
AAGGTCCTCATCGTCACCAGCTTCACCGAGCAGCGCACCGTGGTCCCCGCCCTGCGCGCCGGAGCCTCCGGTTACGTGTA
CAAGGACGTCGACCCGGACGCCCTGGCCGGCGCGATCCGCTCGGTGTACGCGGGCCACGTCCTGCTCCAGCCGGAGGTCG
CGGGGGCCCTGCTCGCCCAGGAGGACTCGGGCAGCGGAACGGGCCGGGGGAGCACCCTCACCGAACGGGAGCGGGAGGTG
CTCGGCCTGATCGCCGACGGCCGCTCCAACCGCGAGATCGCGCGAGCACTGGTCCTCTCCGAGAAGACCGTCAAGACACA
CGTCTCGAACATCCTGATGAAGCTGGACCTCTCGGACCGGACCCAGGCCGCCCTGTGGGCGGTACGGCACGGGGCGGCGG
GCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-207)

Response regulator receiver domain (Response_reg)

(8-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.146

96.262

0.435
  degU Bacillus subtilis subsp. subtilis str. 168

39.367

100

0.407

Multiple sequence alignment