Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   MQP46_RS04160 Genome accession   NZ_CP093935
Coordinates   864679..865107 (+) Length   142 a.a.
NCBI ID   WP_000934385.1    Uniprot ID   A0A2K0CLZ8
Organism   Staphylococcus aureus strain WA121-2021_16354     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 855262..905520 864679..865107 within 0


Gene organization within MGE regions


Location: 855262..905520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MQP46_RS04075 (MQP46_04075) sufB 855262..856659 (+) 1398 WP_001074405.1 Fe-S cluster assembly protein SufB -
  MQP46_RS04080 (MQP46_04080) - 856727..857776 (-) 1050 WP_001145737.1 tyrosine-type recombinase/integrase -
  MQP46_RS04085 (MQP46_04085) - 857889..858068 (+) 180 WP_000337826.1 hypothetical protein -
  MQP46_RS04090 (MQP46_04090) - 858048..858980 (-) 933 WP_000392186.1 hypothetical protein -
  MQP46_RS04095 (MQP46_04095) - 859012..859737 (-) 726 WP_000661437.1 PH domain-containing protein -
  MQP46_RS04100 (MQP46_04100) - 859765..860439 (-) 675 WP_000775187.1 ImmA/IrrE family metallo-endopeptidase -
  MQP46_RS04105 (MQP46_04105) - 860456..860788 (-) 333 WP_001055143.1 helix-turn-helix transcriptional regulator -
  MQP46_RS04110 (MQP46_04110) - 861051..861245 (+) 195 WP_000108122.1 helix-turn-helix transcriptional regulator -
  MQP46_RS04115 (MQP46_04115) - 861245..862012 (+) 768 WP_001002757.1 phage antirepressor Ant -
  MQP46_RS04120 (MQP46_04120) - 862013..862237 (+) 225 WP_000187184.1 hypothetical protein -
  MQP46_RS04125 (MQP46_04125) - 862277..862345 (+) 69 Protein_802 hypothetical protein -
  MQP46_RS04130 (MQP46_04130) - 862366..863031 (-) 666 WP_001807461.1 hypothetical protein -
  MQP46_RS04135 (MQP46_04135) - 863103..863324 (+) 222 WP_221916188.1 hypothetical protein -
  MQP46_RS04140 (MQP46_04140) - 863317..863478 (+) 162 WP_000066011.1 DUF1270 domain-containing protein -
  MQP46_RS04145 (MQP46_04145) - 863572..863832 (+) 261 WP_050960935.1 DUF1108 family protein -
  MQP46_RS04150 (MQP46_04150) - 863842..864063 (+) 222 WP_000815402.1 DUF2483 family protein -
  MQP46_RS04155 (MQP46_04155) - 864056..864679 (+) 624 WP_000139720.1 DUF1071 domain-containing protein -
  MQP46_RS04160 (MQP46_04160) ssbA 864679..865107 (+) 429 WP_000934385.1 single-stranded DNA-binding protein Machinery gene
  MQP46_RS04165 (MQP46_04165) - 865121..865795 (+) 675 WP_020444663.1 putative HNHc nuclease -
  MQP46_RS04170 (MQP46_04170) - 865905..866564 (-) 660 WP_016028252.1 hypothetical protein -
  MQP46_RS04175 (MQP46_04175) - 866610..867380 (+) 771 WP_000190226.1 conserved phage C-terminal domain-containing protein -
  MQP46_RS04180 (MQP46_04180) - 867390..868163 (+) 774 WP_000803028.1 ATP-binding protein -
  MQP46_RS04185 (MQP46_04185) - 868157..868315 (+) 159 WP_000256597.1 hypothetical protein -
  MQP46_RS04190 (MQP46_04190) - 868329..868550 (+) 222 WP_089519265.1 DUF3269 family protein -
  MQP46_RS04195 (MQP46_04195) - 868561..868965 (+) 405 WP_000049795.1 DUF1064 domain-containing protein -
  MQP46_RS04200 (MQP46_04200) - 868970..869155 (+) 186 WP_001187244.1 DUF3113 family protein -
  MQP46_RS04205 (MQP46_04205) - 869156..869527 (+) 372 WP_001140291.1 SA1788 family PVL leukocidin-associated protein -
  MQP46_RS04210 (MQP46_04210) - 869527..869781 (+) 255 WP_000022719.1 DUF3310 domain-containing protein -
  MQP46_RS04215 (MQP46_04215) - 869781..870029 (+) 249 WP_060474161.1 SAV1978 family virulence-associated passenger protein -
  MQP46_RS04220 (MQP46_04220) - 870043..870249 (+) 207 WP_000693989.1 hypothetical protein -
  MQP46_RS04225 (MQP46_04225) - 870252..870656 (+) 405 WP_000695756.1 hypothetical protein -
  MQP46_RS04230 (MQP46_04230) - 870653..871069 (+) 417 WP_000175227.1 YopX family protein -
  MQP46_RS04235 (MQP46_04235) - 871066..871431 (+) 366 WP_001105613.1 hypothetical protein -
  MQP46_RS04240 (MQP46_04240) - 871424..871678 (+) 255 WP_001065113.1 DUF1024 family protein -
  MQP46_RS04245 (MQP46_04245) - 871665..871835 (+) 171 WP_000714413.1 hypothetical protein -
  MQP46_RS04250 (MQP46_04250) - 871828..872364 (+) 537 WP_000181824.1 dUTPase -
  MQP46_RS04255 (MQP46_04255) - 872401..872688 (+) 288 WP_000195742.1 DUF1381 domain-containing protein -
  MQP46_RS04260 (MQP46_04260) - 872681..872917 (+) 237 WP_000608282.1 hypothetical protein -
  MQP46_RS04265 (MQP46_04265) - 872907..873296 (+) 390 WP_078064095.1 hypothetical protein -
  MQP46_RS04270 (MQP46_04270) - 873293..873466 (+) 174 WP_000595302.1 transcriptional activator RinB -
  MQP46_RS04275 (MQP46_04275) - 873467..873868 (+) 402 WP_000286968.1 hypothetical protein -
  MQP46_RS04280 (MQP46_04280) - 874223..874717 (+) 495 WP_000594088.1 terminase small subunit -
  MQP46_RS04285 (MQP46_04285) - 874710..875933 (+) 1224 WP_001037578.1 PBSX family phage terminase large subunit -
  MQP46_RS04290 (MQP46_04290) - 875930..877354 (+) 1425 WP_000177422.1 phage portal protein -
  MQP46_RS04295 (MQP46_04295) - 877323..878276 (+) 954 WP_000184143.1 phage head morphogenesis protein -
  MQP46_RS04300 (MQP46_04300) - 878278..878484 (+) 207 WP_000346033.1 hypothetical protein -
  MQP46_RS04305 (MQP46_04305) - 878587..879171 (+) 585 WP_001019220.1 DUF4355 domain-containing protein -
  MQP46_RS04310 (MQP46_04310) - 879188..880102 (+) 915 WP_000235168.1 phage major capsid protein -
  MQP46_RS04315 (MQP46_04315) - 880114..880257 (+) 144 WP_000002931.1 hypothetical protein -
  MQP46_RS04320 (MQP46_04320) - 880263..880613 (+) 351 WP_000177351.1 phage head-tail adapter protein -
  MQP46_RS04325 (MQP46_04325) - 880625..880960 (+) 336 WP_000483041.1 phage head closure protein -
  MQP46_RS04330 (MQP46_04330) - 880947..881354 (+) 408 WP_001151323.1 HK97-gp10 family putative phage morphogenesis protein -
  MQP46_RS04335 (MQP46_04335) - 881367..881792 (+) 426 WP_000270189.1 DUF3168 domain-containing protein -
  MQP46_RS04340 (MQP46_04340) - 881793..882350 (+) 558 WP_000057582.1 tail protein -
  MQP46_RS04345 (MQP46_04345) - 882417..882923 (+) 507 WP_000134337.1 tail assembly chaperone -
  MQP46_RS04350 (MQP46_04350) - 882968..883252 (+) 285 WP_000880588.1 hypothetical protein -
  MQP46_RS04355 (MQP46_04355) - 883256..886141 (+) 2886 WP_000379450.1 terminase -
  MQP46_RS04360 (MQP46_04360) - 886156..887097 (+) 942 WP_000560187.1 phage tail domain-containing protein -
  MQP46_RS04365 (MQP46_04365) - 887108..888994 (+) 1887 WP_001121997.1 phage tail protein -
  MQP46_RS04370 (MQP46_04370) - 889007..890905 (+) 1899 WP_064133579.1 hypothetical protein -
  MQP46_RS04375 (MQP46_04375) - 890905..892728 (+) 1824 WP_000634514.1 BppU family phage baseplate upper protein -
  MQP46_RS04380 (MQP46_04380) - 892728..893105 (+) 378 WP_000705914.1 DUF2977 domain-containing protein -
  MQP46_RS04385 (MQP46_04385) - 893115..893288 (+) 174 WP_001790193.1 XkdX family protein -
  MQP46_RS04390 (MQP46_04390) - 893329..893628 (+) 300 WP_000466769.1 DUF2951 domain-containing protein -
  MQP46_RS04395 (MQP46_04395) - 893765..895639 (+) 1875 WP_000524049.1 glucosaminidase domain-containing protein -
  MQP46_RS04400 (MQP46_04400) - 895652..896890 (+) 1239 WP_000276651.1 BppU family phage baseplate upper protein -
  MQP46_RS04405 (MQP46_04405) - 896895..897290 (+) 396 WP_000398877.1 hypothetical protein -
  MQP46_RS04410 (MQP46_04410) - 897346..897621 (+) 276 WP_000351119.1 phage holin -
  MQP46_RS04415 (MQP46_04415) - 897608..899020 (+) 1413 WP_001141520.1 N-acetylmuramoyl-L-alanine amidase -
  MQP46_RS04420 (MQP46_04420) - 899080..899637 (-) 558 WP_001035621.1 DUF4888 domain-containing protein -
  MQP46_RS04425 (MQP46_04425) - 900502..900641 (+) 140 Protein_862 hypothetical protein -
  MQP46_RS04430 (MQP46_04430) - 900647..900961 (-) 315 WP_000274029.1 hypothetical protein -
  MQP46_RS04435 (MQP46_04435) - 901326..902366 (+) 1041 WP_000582326.1 CNNM domain-containing protein -
  MQP46_RS04440 (MQP46_04440) - 902380..903447 (+) 1068 WP_000267236.1 nitronate monooxygenase family protein -
  MQP46_RS04445 (MQP46_04445) - 903701..903784 (+) 84 WP_016170465.1 hypothetical protein -
  MQP46_RS04450 (MQP46_04450) - 903832..904680 (+) 849 WP_000608129.1 DUF72 domain-containing protein -
  MQP46_RS04455 (MQP46_04455) - 904693..905520 (+) 828 WP_000927632.1 sulfite exporter TauE/SafE family protein -

Sequence


Protein


Download         Length: 142 a.a.        Molecular weight: 15872.58 Da        Isoelectric Point: 8.4825

>NTDB_id=665708 MQP46_RS04160 WP_000934385.1 864679..865107(+) (ssbA) [Staphylococcus aureus strain WA121-2021_16354]
MLNRAVLVGRLTKDPELRSAPNGVNVGTFTLAVNRTFTNAQGEREADFINVVVFKKQAENVKNYLSKGSLAGVDGRLQTR
SYENKVGQRVFVTEVVADSVQFLEPKNNNQQPNNNYHQQRQTQTGNNPFDNTTAITDDDLPF

Nucleotide


Download         Length: 429 bp        

>NTDB_id=665708 MQP46_RS04160 WP_000934385.1 864679..865107(+) (ssbA) [Staphylococcus aureus strain WA121-2021_16354]
ATGTTAAACAGAGCAGTATTAGTAGGACGCTTAACAAAAGACCCAGAATTAAGAAGCGCGCCAAATGGCGTAAATGTAGG
TACATTCACATTGGCAGTAAACAGAACATTCACGAATGCTCAAGGCGAGCGTGAAGCAGATTTTATAAACGTAGTAGTGT
TCAAGAAACAAGCTGAAAATGTTAAAAACTACCTTTCTAAAGGGTCGCTGGCAGGTGTAGACGGGCGACTACAAACACGT
AGCTACGAAAATAAAGTCGGGCAACGTGTATTTGTGACAGAAGTAGTAGCGGACAGTGTTCAATTCTTAGAACCGAAGAA
TAACAACCAACAACCAAACAACAATTATCATCAACAAAGACAAACTCAAACTGGTAATAATCCTTTTGATAATACCACTG
CGATTACTGATGATGACTTACCGTTCTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A2K0CLZ8

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

58.14

100

0.704

  ssb Latilactobacillus sakei subsp. sakei 23K

50.588

100

0.606

  ssbB Bacillus subtilis subsp. subtilis str. 168

58.491

74.648

0.437

  ssbB Streptococcus sobrinus strain NIDR 6715-7

41.958

100

0.423

  ssbA Streptococcus mutans UA159

40.845

100

0.408

  ssbB/cilA Streptococcus mitis NCTC 12261

40.141

100

0.401

  ssbB/cilA Streptococcus pneumoniae TIGR4

40.141

100

0.401

  ssbB/cilA Streptococcus pneumoniae Rx1

39.437

100

0.394

  ssbB/cilA Streptococcus pneumoniae D39

39.437

100

0.394

  ssbB/cilA Streptococcus pneumoniae R6

39.437

100

0.394

  ssbB/cilA Streptococcus mitis SK321

39.437

100

0.394