Detailed information NTG0065498

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: ANG_RS00690
• Genome accession: NZ_AP013072
• Coordinates: 126000..126749 (+)
• Length: 249 a.a.
• NCBI ID: WP_003038257.1
• Uniprot ID: -
• Organism: Streptococcus anginosus subsp. whileyi MAS624
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 121000..131749

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ANG_RS00660 (ANG_0112)	spo0J	121547..122314 (-)	768	WP_025271549.1	ParB/RepB/Spo0J family partition protein	Regulator
ANG_RS00665 (ANG_0113)	htrA	122369..123559 (-)	1191	WP_003032033.1	S1C family serine protease	Regulator
ANG_RS00670 (ANG_0114)	rlmH	123753..124232 (+)	480	WP_004225060.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ANG_RS10760 (ANG_0115)	-	124514..124663 (+)	150	WP_003038250.1	bacteriocin	-
ANG_RS00685 (ANG_0116)	comD/comD2	124678..126000 (+)	1323	WP_003038254.1	GHKL domain-containing protein	Regulator
ANG_RS00690 (ANG_0117)	comE/comE2	126000..126749 (+)	750	WP_003038257.1	competence system response regulator transcription factor ComE	Regulator
ANG_RS00705 (ANG_0118)	-	127096..129672 (-)	2577	WP_004225037.1	YfhO family protein	-
ANG_RS00710 (ANG_0119)	-	129746..131368 (-)	1623	WP_003038260.1	ATP-binding cassette domain-containing protein	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29216.88 Da
• Isoelectric Point: 8.6042

>NTDB_id=65498 ANG_RS00690 WP_003038257.1 126000..126749(+) (comE/comE2) [Streptococcus anginosus subsp. whileyi MAS624]
MKVLVLEDEITHQVRMETTLAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFIRHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSDVAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKLGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=65498 ANG_RS00690 WP_003038257.1 126000..126749(+) (comE/comE2) [Streptococcus anginosus subsp. whileyi MAS624]
ATGAAAGTATTAGTATTAGAAGATGAAATTACACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCAAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGAAAAGTAAGGGAATTTAAAGAATATATTGAAAACGATGAAGTAAATCAAT
TATATTTTTTAGATATTGATATTAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATACGTCATCACAATCCG
TATGCCATTATTGTTTTTGTTACAACGAAATCAGAATTTGCCACTATGACCTTCAAATATAAGGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTGATGTTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGCTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTCTATGGCACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCCTACCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAACTTGGAAAATTA
AAAGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	70.492	97.992	0.691
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.492	97.992	0.691
comE	Streptococcus mitis NCTC 12261	70.204	98.394	0.691
comE	Streptococcus infantis strain Atu-4	69.796	98.394	0.687
comE	Streptococcus mitis SK321	69.388	98.394	0.683
comE	Streptococcus pneumoniae Rx1	68.98	98.394	0.679
comE	Streptococcus pneumoniae D39	68.98	98.394	0.679
comE	Streptococcus pneumoniae R6	68.98	98.394	0.679
comE	Streptococcus pneumoniae TIGR4	68.98	98.394	0.679
comE/blpR	Streptococcus mutans UA159	40.891	99.197	0.406