Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   OG985_RS35300 Genome accession   NZ_CP108046
Coordinates   7802852..7803493 (+) Length   213 a.a.
NCBI ID   WP_371672424.1    Uniprot ID   -
Organism   Streptomyces sp. NBC_00289     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7797852..7808493
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OG985_RS35280 (OG985_35170) - 7798638..7799390 (-) 753 WP_371672420.1 transglycosylase SLT domain-containing protein -
  OG985_RS35285 (OG985_35175) - 7799688..7800806 (-) 1119 WP_371672421.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  OG985_RS35290 (OG985_35180) - 7800803..7801498 (-) 696 WP_371672422.1 SDR family NAD(P)-dependent oxidoreductase -
  OG985_RS35295 (OG985_35185) - 7801714..7802859 (+) 1146 WP_371672423.1 GAF domain-containing sensor histidine kinase -
  OG985_RS35300 (OG985_35190) vraR 7802852..7803493 (+) 642 WP_371672424.1 response regulator Regulator
  OG985_RS35305 (OG985_35195) chpE 7803673..7803918 (+) 246 WP_371672425.1 chaplin ChpE -
  OG985_RS35310 (OG985_35200) - 7804071..7804310 (+) 240 WP_371672426.1 chaplin family protein -
  OG985_RS35315 (OG985_35205) - 7804474..7805253 (-) 780 WP_371672427.1 hypothetical protein -
  OG985_RS35320 (OG985_35210) - 7805406..7806203 (+) 798 WP_371672428.1 ABC transporter ATP-binding protein -
  OG985_RS35325 (OG985_35215) - 7806297..7806728 (+) 432 WP_371672430.1 NfeD family protein -
  OG985_RS35330 (OG985_35220) - 7806860..7807828 (+) 969 WP_371672431.1 SPFH domain-containing protein -
  OG985_RS35335 (OG985_35225) - 7807907..7808413 (-) 507 WP_371672432.1 HNH endonuclease -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23007.34 Da        Isoelectric Point: 5.9539

>NTDB_id=652035 OG985_RS35300 WP_371672424.1 7802852..7803493(+) (vraR) [Streptomyces sp. NBC_00289]
MADAIRVLLVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARTEELKPDVVLMDVKMPGMDGVEALRKLRELNNPAR
VLIVTSFTEQRTVVPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGALLSQEVTNSGHGRGGSLTEREREVL
TLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGVTG

Nucleotide


Download         Length: 642 bp        

>NTDB_id=652035 OG985_RS35300 WP_371672424.1 7802852..7803493(+) (vraR) [Streptomyces sp. NBC_00289]
GTGGCTGACGCGATCAGGGTGTTGCTCGTCGACGACCACCAGGTGGTCCGCCGGGGCCTGCGCACCTTCCTCGAGGTGCA
GGACGACATCGAGGTCGTGGGCGAGGCGGCGGACGGCGCCGAAGGAGTCGCCCGCACCGAGGAACTGAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGTGTCGAGGCCCTGCGCAAGCTGCGCGAACTGAACAACCCCGCGCGC
GTGCTGATCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTCCCGGCCCTGCGCGCGGGAGCCGCCGGTTACGTGTACAA
GGACGTCGACCCCGACGCCCTGGCCGGCGCCATCCGCTCCGTCCACGCCGGCCACATCCTGCTCCAACCCGAGGTCGCGG
GCGCCCTGTTGTCCCAGGAGGTGACCAACTCGGGCCACGGCAGGGGCGGTTCGCTGACGGAGCGGGAGCGGGAGGTGCTG
ACCCTGATAGCGGACGGCCGCTCCAACCGGGAGATCGCCCGAGCGCTGGTGCTCTCCGAGAAGACCGTCAAGACGCACGT
CTCGAACATCCTGATGAAACTCGACCTCGCCGACCGCACCCAGGCCGCGCTGTGGGCCGTCCGCCATGGCGTGACCGGCT
GA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(151-206)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

46.19

98.592

0.455
  degU Bacillus subtilis subsp. subtilis str. 168

39.819

100

0.413