Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   L1871_RS19735 Genome accession   NZ_CP091176
Coordinates   4183607..4184848 (+) Length   413 a.a.
NCBI ID   WP_010675822.1    Uniprot ID   A0A2L0TT63
Organism   Aeromonas caviae strain SCLZS52     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4178607..4189848
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1871_RS19710 (L1871_19705) ampD 4178971..4179543 (-) 573 WP_039040507.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  L1871_RS19715 (L1871_19710) - 4179672..4180142 (+) 471 WP_042015101.1 TIGR02281 family clan AA aspartic protease -
  L1871_RS19720 (L1871_19715) nadC 4180146..4181009 (+) 864 WP_052814467.1 carboxylating nicotinate-nucleotide diphosphorylase -
  L1871_RS19725 (L1871_19720) tapA 4181332..4181769 (+) 438 WP_104456018.1 type IVa pilus major pilin TapA -
  L1871_RS19730 (L1871_19725) pilB 4181773..4183479 (+) 1707 WP_104454847.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  L1871_RS19735 (L1871_19730) pilC 4183607..4184848 (+) 1242 WP_010675822.1 type II secretion system F family protein Machinery gene
  L1871_RS19740 (L1871_19735) pilD 4184926..4185801 (+) 876 WP_103261555.1 prepilin peptidase Machinery gene
  L1871_RS19745 (L1871_19740) coaE 4185820..4186434 (+) 615 WP_052814464.1 dephospho-CoA kinase -
  L1871_RS19750 (L1871_19745) zapD 4186472..4187194 (+) 723 WP_010675825.1 cell division protein ZapD -
  L1871_RS19755 (L1871_19750) yacG 4187205..4187399 (+) 195 WP_103858092.1 DNA gyrase inhibitor YacG -
  L1871_RS19760 (L1871_19755) mutT 4187457..4187861 (-) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  L1871_RS19765 (L1871_19760) - 4187870..4189054 (-) 1185 WP_103858093.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45435.37 Da        Isoelectric Point: 9.9380

>NTDB_id=648197 L1871_RS19735 WP_010675822.1 4183607..4184848(+) (pilC) [Aeromonas caviae strain SCLZS52]
MATLAQKRNAPKKVFSYRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQSQGLFSKGGAKIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVIAISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=648197 L1871_RS19735 WP_010675822.1 4183607..4184848(+) (pilC) [Aeromonas caviae strain SCLZS52]
ATGGCCACATTAGCTCAAAAACGCAACGCACCGAAAAAAGTCTTCTCCTACCGCTGGCACGGCGTCAACCGCAAGGGACA
GAAGGTCTCCGGCGAGCTGCAAGCCGACAGCATCACCACCGTCAAGGCCGAGCTGCGCAAGCAGGGCGTCAACGTCACCA
GGGTCAGCAAGCAGAGCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCCGCCGGCGTGCCTCTGGTGCAGAGTCTTCAGATCATTGCTCGCGGCCACGAGAAAGCGGC
GGTGCGCGAACTCATCGGCCAGATCGCCGCCGATGTGGAAACGGGCACCCCGCTCTCGGAGGCGTTGCGCCGCCATCCCC
GCCACTTCGACGACCTCTATTGCGACCTGGTCGAGGCCGGGGAGCAATCCGGTGCCCTGGAGACCATCTACGACCGTATC
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTCACCCGGTTCGTCATCGCCATCTCCCGCTTCATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCGGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCGCTGGTGGATGCCCTGGTCTCGGCGGCTGGAGCATCGGGCAACTATGTCTATCGCACTGCGACCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGTGAGGAATCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATTTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTCGAACCCATCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0TT63

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Legionella pneumophila strain ERS1305867

52.099

98.063

0.511
  pilC Acinetobacter baylyi ADP1

50.971

99.758

0.508
  pilC Acinetobacter baumannii D1279779

52.369

97.094

0.508
  pilC Vibrio cholerae strain A1552

47.368

96.61

0.458
  pilC Vibrio campbellii strain DS40M4

45.113

96.61

0.436
  pilG Neisseria meningitidis 44/76-A

41.602

93.705

0.39
  pilG Neisseria gonorrhoeae MS11

41.602

93.705

0.39
  pilC Thermus thermophilus HB27

38.75

96.852

0.375