Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   LV497_RS07140 Genome accession   NZ_CP090007
Coordinates   1550208..1550942 (+) Length   244 a.a.
NCBI ID   WP_245084355.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1545208..1555942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS07125 (LV497_07125) - 1546108..1546800 (+) 693 WP_245084349.1 DUF6287 domain-containing protein -
  LV497_RS07130 (LV497_07130) - 1546865..1547164 (+) 300 WP_084914952.1 hypothetical protein -
  LV497_RS07135 (LV497_07135) - 1547441..1549996 (+) 2556 WP_245084352.1 SH3 domain-containing protein -
  LV497_RS07140 (LV497_07140) comE/blpR 1550208..1550942 (+) 735 WP_245084355.1 LytTR family DNA-binding domain-containing protein Regulator
  LV497_RS07145 (LV497_07145) - 1550939..1552258 (+) 1320 WP_245084358.1 sensor histidine kinase -
  LV497_RS07150 (LV497_07150) - 1552356..1553009 (+) 654 WP_245084361.1 DUF6287 domain-containing protein -

Sequence

Protein


Download         Length: 244 a.a.        Molecular weight: 28582.95 Da        Isoelectric Point: 6.3900

>NTDB_id=640145 LV497_RS07140 WP_245084355.1 1550208..1550942(+) (comE/blpR) [Streptococcus salivarius strain SALI-10]
MLNIYVLEDHFIQQNRIEEVIHTILKKNNIKVGDFEVFDKPNQLLESITERGSHQLFFLDIQIKDDTKKGLEVAKQIRKN
DPYANIVFFTTHSEYLPLTFQYQLAALDFIDKSLEGEDFQKRVESIILLTCKKIQSQNPEDAFRIENVKTVIQVPFHDIL
YFETSDIVHKVILYTKEEQIEFYGSLSQIEKSDPRLFKCHKSFLINPENIIKLDKSTGTVYFENGGVCYVSKLKLKKLIE
RISL

Nucleotide


Download         Length: 735 bp        

>NTDB_id=640145 LV497_RS07140 WP_245084355.1 1550208..1550942(+) (comE/blpR) [Streptococcus salivarius strain SALI-10]
ATGCTTAACATCTATGTTTTAGAGGATCATTTTATCCAACAAAATCGTATTGAAGAGGTTATTCATACGATTCTTAAGAA
AAATAATATTAAAGTGGGTGACTTTGAGGTTTTTGACAAACCCAATCAACTGTTAGAGTCTATTACCGAGCGAGGGTCTC
ATCAGCTCTTTTTCTTGGACATTCAAATTAAAGACGATACTAAAAAAGGTTTGGAAGTGGCTAAGCAGATTCGCAAGAAT
GATCCCTATGCCAATATTGTTTTCTTCACGACTCATTCAGAGTATCTTCCCTTAACTTTTCAATACCAACTGGCAGCTCT
AGACTTTATTGATAAGTCTTTGGAGGGTGAGGACTTTCAAAAGCGTGTGGAAAGTATTATCTTATTAACCTGCAAAAAGA
TACAGAGTCAGAATCCAGAAGACGCTTTTCGGATTGAGAATGTAAAGACCGTTATTCAGGTTCCCTTTCATGATATCTTG
TACTTTGAGACGTCAGATATTGTTCATAAGGTTATCCTTTATACTAAAGAGGAGCAGATTGAGTTTTATGGCAGTCTCTC
ACAAATCGAAAAGAGTGACCCTAGACTGTTTAAATGCCACAAATCTTTCCTTATCAATCCAGAAAATATCATCAAATTAG
ATAAGAGTACGGGGACGGTCTATTTTGAAAATGGTGGTGTCTGCTATGTTTCAAAGTTGAAATTAAAGAAATTGATTGAG
AGAATCAGCCTATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-123)

LytTr DNA-binding domain (LytTR)

(151-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.883

97.951

0.508
  comE/comE1 Streptococcus equinus JB1

47.699

97.951

0.467
  comE/comE2 Streptococcus equinus JB1

43.277

97.541

0.422
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.683

99.59

0.385
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.683

99.59

0.385
  comE Streptococcus infantis strain Atu-4

37.759

98.77

0.373
  comE Streptococcus pneumoniae D39

37.344

98.77

0.369
  comE Streptococcus pneumoniae R6

37.344

98.77

0.369
  comE Streptococcus pneumoniae Rx1

37.344

98.77

0.369
  comE Streptococcus mitis SK321

37.344

98.77

0.369
  comE Streptococcus mitis NCTC 12261

37.344

98.77

0.369
  comE Streptococcus pneumoniae TIGR4

37.344

98.77

0.369