Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LSP22_RS07510 Genome accession   NZ_CP089064
Coordinates   1597196..1598413 (+) Length   405 a.a.
NCBI ID   WP_023103506.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain UNC_PaerCF35     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1592196..1603413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSP22_RS07480 (LSP22_07480) nadC 1592843..1593691 (+) 849 WP_021264134.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LSP22_RS07490 (LSP22_07490) tfpZ 1593924..1594661 (-) 738 WP_023100229.1 TfpX/TfpZ family type IV pilin accessory protein -
  LSP22_RS07495 (LSP22_07495) pilE 1594726..1595262 (-) 537 WP_277989274.1 pilin Machinery gene
  LSP22_RS07505 (LSP22_07505) pilB 1595489..1597192 (+) 1704 WP_023100230.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LSP22_RS07510 (LSP22_07510) pilC 1597196..1598413 (+) 1218 WP_023103506.1 type II secretion system F family protein Machinery gene
  LSP22_RS07515 (LSP22_07515) pilD 1598416..1599288 (+) 873 WP_231822116.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  LSP22_RS07520 (LSP22_07520) coaE 1599285..1599896 (+) 612 WP_003112838.1 dephospho-CoA kinase -
  LSP22_RS07525 (LSP22_07525) yacG 1599893..1600093 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  LSP22_RS07530 (LSP22_07530) - 1600130..1600339 (-) 210 WP_003094660.1 hypothetical protein -
  LSP22_RS07535 (LSP22_07535) - 1600445..1601134 (-) 690 WP_003094662.1 energy-coupling factor ABC transporter permease -
  LSP22_RS07540 (LSP22_07540) - 1601131..1601601 (-) 471 WP_003094664.1 hypothetical protein -
  LSP22_RS07545 (LSP22_07545) - 1601598..1602023 (-) 426 WP_003103865.1 GNAT family N-acetyltransferase -
  LSP22_RS07550 (LSP22_07550) - 1602156..1602785 (+) 630 WP_003094668.1 DUF1780 domain-containing protein -
  LSP22_RS07555 (LSP22_07555) - 1602782..1603231 (+) 450 WP_003094670.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 43875.86 Da        Isoelectric Point: 9.9457

>NTDB_id=635011 LSP22_RS07510 WP_023103506.1 1597196..1598413(+) (pilC) [Pseudomonas aeruginosa strain UNC_PaerCF35]
MADKALKTSVFIWEGTDKKGSKVKGELTGQNPMLVKAQLRKQGINPLKVRKKGITLFGAGKKIKPMDIALFTRQMATMMG
AGVPLLQSFDIIGEGFENPNMRKLVDEIKQEVAAGNSLANSLRKKPQYFDDLYCNLVDAGEQSGALETLLARVATYKEKT
EALKAKIKKAMTYPIAVVIVALVVSAILLIKVVPQFQSVFANFGAELPAFTQMVIGLSETLQEWWLLVLIAMLGIGFALK
ELYKRSKSFRDTIDRAILKAPIVGAIVYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFKSAVAKIKQDVSSGM
QLNFSMRTTNVFPSMAIQMAAIGEESGSLDDMLGKVAGFYEDEVDNAVDNLTTLMEPMIMAVLGVLVGGLIVAMYLPIFQ
LGKVI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=635011 LSP22_RS07510 WP_023103506.1 1597196..1598413(+) (pilC) [Pseudomonas aeruginosa strain UNC_PaerCF35]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCATCTGGGAAGGTACTGATAAGAAGGGCAGCAAGGTCAAAGGAGAGTT
GACCGGGCAAAACCCTATGCTGGTCAAAGCCCAGCTACGCAAACAGGGTATCAATCCGCTGAAAGTCCGCAAGAAAGGCA
TCACGCTATTCGGTGCGGGAAAAAAAATCAAACCCATGGACATCGCACTGTTCACTCGGCAGATGGCGACCATGATGGGC
GCAGGCGTGCCCCTATTGCAGTCCTTCGACATCATTGGCGAGGGCTTCGAAAATCCGAACATGCGAAAGCTGGTTGACGA
AATAAAGCAGGAAGTCGCAGCCGGTAATAGCTTGGCCAACTCACTACGAAAGAAGCCCCAGTATTTTGACGACCTTTACT
GCAATCTTGTAGATGCGGGCGAACAATCAGGCGCATTGGAAACGCTTCTCGCCCGGGTTGCTACCTACAAGGAAAAAACT
GAGGCACTCAAAGCCAAGATCAAGAAAGCTATGACCTACCCCATCGCGGTCGTTATCGTGGCACTGGTGGTCTCTGCGAT
CCTACTCATTAAGGTTGTTCCGCAATTCCAGTCAGTTTTCGCGAACTTTGGTGCAGAGCTACCAGCCTTCACTCAAATGG
TGATCGGACTTTCGGAAACATTACAAGAATGGTGGCTACTTGTCCTCATCGCCATGCTCGGCATAGGTTTTGCTCTGAAA
GAGTTGTACAAGCGCTCCAAAAGTTTCCGCGACACCATAGACAGAGCCATACTGAAAGCTCCCATCGTCGGTGCCATCGT
CTATAAGTCAGCCGTAGCACGTTATGCACGGACCCTATCGACTACGTTTGCAGCAGGCGTTCCTCTAGTCGAGGCTTTGG
ATTCGGTATCAGGGGCCACAGGTAATGTGGTGTTTAAAAGCGCAGTCGCCAAGATCAAGCAGGACGTTTCCAGCGGTATG
CAGTTGAACTTCTCCATGCGCACCACCAATGTTTTTCCGAGTATGGCTATCCAGATGGCTGCGATTGGCGAAGAATCTGG
TTCGCTGGACGACATGCTTGGCAAAGTGGCTGGCTTCTACGAGGATGAAGTAGATAATGCCGTCGACAATTTGACGACTT
TGATGGAACCAATGATCATGGCGGTGCTGGGAGTCCTGGTTGGCGGATTGATCGTCGCTATGTATCTGCCTATTTTCCAG
CTCGGCAAAGTTATCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

79.506

100

0.795
  pilC Acinetobacter baylyi ADP1

58.968

100

0.593
  pilC Acinetobacter baumannii D1279779

59.158

99.753

0.59
  pilC Legionella pneumophila strain ERS1305867

53.535

97.778

0.523
  pilG Neisseria meningitidis 44/76-A

45.926

100

0.459
  pilG Neisseria gonorrhoeae MS11

45.679

100

0.457
  pilC Vibrio cholerae strain A1552

42.963

100

0.43
  pilC Vibrio campbellii strain DS40M4

41.414

97.778

0.405
  pilC Thermus thermophilus HB27

37.406

99.012

0.37