Detailed information NTG0062921

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: N597_RS07570
• Genome accession: NC_022582
• Coordinates: 1560877..1561614 (+)
• Length: 245 a.a.
• NCBI ID: WP_023024408.1
• Uniprot ID: -
• Organism: Streptococcus ilei
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1559113..1560464	1560877..1561614	flank	413

Gene organization within MGE regions

Location: 1559113..1561614

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N597_RS09955	-	1559113..1560464 (+)	1352	WP_398575108.1	IS3 family transposase	-
N597_RS07570 (N597_07800)	comE/blpR	1560877..1561614 (+)	738	WP_023024408.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28431.42 Da
• Isoelectric Point: 6.6627

>NTDB_id=62921 N597_RS07570 WP_023024408.1 1560877..1561614(+) (comE/blpR) [Streptococcus ilei]
MLNIFVLEDDFLQQTRIETAIKKCMTDHHLKYKYLEVFGKPTQLLEAIKETGNHQFFFLDIEIKGEEKKGMEIAREIRDK
DPSASIVFVTTHSEFMPVTYRYRVSALDFIDKGLNDQDYQEAISSVLIHATENVNKTVGEDSFSFKSEHSQIQVPFSDIL
YFETSSTVHKVVLTTKKGHMEFYGKVSDIAKTDKRLYQSHRAYVVNPENVVRIDKANHIVYFENDESCFVSRLKLKGLVE
KVDKK

Nucleotide

• Length: 738 bp

>NTDB_id=62921 N597_RS07570 WP_023024408.1 1560877..1561614(+) (comE/blpR) [Streptococcus ilei]
ATGCTAAATATCTTTGTATTAGAAGATGATTTTCTACAACAAACTCGTATTGAAACAGCAATCAAGAAATGTATGACAGA
TCATCATCTAAAGTATAAATACTTAGAGGTATTTGGGAAGCCAACACAATTGTTAGAGGCCATCAAAGAGACAGGGAATC
ACCAATTCTTTTTTTTAGATATTGAAATTAAAGGGGAAGAAAAAAAAGGAATGGAAATTGCGCGTGAGATTCGTGATAAA
GATCCTAGCGCTTCAATCGTATTCGTAACGACTCACTCAGAATTCATGCCCGTTACCTATCGTTATCGCGTCTCCGCTTT
GGATTTTATTGATAAAGGATTAAATGATCAGGATTATCAAGAAGCGATCTCATCTGTTTTGATACATGCTACTGAAAACG
TCAATAAGACAGTAGGGGAGGATTCCTTCAGCTTTAAATCAGAGCATTCCCAGATTCAAGTCCCTTTCTCAGATATTCTA
TATTTTGAGACATCTTCGACCGTTCATAAGGTCGTTTTAACAACTAAAAAAGGCCACATGGAATTTTATGGTAAAGTCTC
AGATATTGCTAAAACCGACAAGCGACTTTACCAAAGTCATCGAGCTTACGTTGTAAATCCAGAGAATGTCGTTCGTATTG
ATAAAGCAAATCATATTGTTTATTTTGAAAACGATGAATCATGCTTTGTATCACGTTTAAAACTGAAAGGGCTAGTTGAA
AAGGTAGATAAAAAATGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	57.741	97.551	0.563
comE/comE1	Streptococcus equinus JB1	48.76	98.776	0.482
comE/comE2	Streptococcus equinus JB1	39.918	99.184	0.396
comE	Streptococcus infantis strain Atu-4	36.546	100	0.371
comE	Streptococcus mitis NCTC 12261	36.145	100	0.367
comE	Streptococcus pneumoniae R6	36.145	100	0.367
comE	Streptococcus pneumoniae TIGR4	36.145	100	0.367
comE	Streptococcus mitis SK321	36.145	100	0.367
comE	Streptococcus pneumoniae Rx1	36.145	100	0.367
comE	Streptococcus pneumoniae D39	36.145	100	0.367
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	36.626	99.184	0.363
comE/comE2	Streptococcus gordonii strain NCTC7865	36.626	99.184	0.363