Detailed information NTG0622356

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: LL047_RS11545
• Genome accession: NZ_CP086072
• Coordinates: 2247503..2248441 (-)
• Length: 312 a.a.
• NCBI ID: WP_010906320.1
• Uniprot ID: A0AAC9W673
• Organism: Lactococcus lactis subsp. lactis strain EIP33
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2242503..2253441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL047_RS11505 (LL047_11470)	-	2243391..2244233 (-)	843	WP_010906312.1	metal ABC transporter substrate-binding protein	-
LL047_RS11510 (LL047_11475)	-	2244230..2244667 (-)	438	WP_010906313.1	zinc-dependent MarR family transcriptional regulator	-
LL047_RS11515 (LL047_11480)	comGG	2244748..2245032 (-)	285	WP_010906314.1	competence type IV pilus minor pilin ComGG	Machinery gene
LL047_RS11520 (LL047_11485)	comGF	2245071..2245517 (-)	447	WP_031296844.1	competence type IV pilus minor pilin ComGF	Machinery gene
LL047_RS11525 (LL047_11490)	comGE	2245480..2245776 (-)	297	WP_010906316.1	competence type IV pilus minor pilin ComGE	Machinery gene
LL047_RS11530 (LL047_11495)	comGD	2245748..2246146 (-)	399	WP_021214886.1	competence type IV pilus minor pilin ComGD	Machinery gene
LL047_RS11535 (LL047_11500)	comGC	2246139..2246522 (-)	384	WP_010906318.1	competence type IV pilus major pilin ComGC	Machinery gene
LL047_RS11540 (LL047_11505)	comGB	2246536..2247609 (-)	1074	WP_010906319.1	competence type IV pilus assembly protein ComGB	Machinery gene
LL047_RS11545 (LL047_11510)	comGA	2247503..2248441 (-)	939	WP_010906320.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35719.89 Da
• Isoelectric Point: 6.1804

>NTDB_id=622356 LL047_RS11545 WP_010906320.1 2247503..2248441(-) (comGA) [Lactococcus lactis subsp. lactis strain EIP33]
MIPKMAKELIQRAIDRDASDIYLIASKEKYKLYFRQMTARDLVEEIGLEVGLALLTHFKFLAGMNTGERRRVQLGACWYE
IEESNAKRLRLSTVGDFEGNESLVIRLLHDQNKELDFWFDQELENYDCKRGLHLFAGPVGSGKTSLMFDLARRHFTDLQV
INIEEPVELIDSDFIQLQVNEVIGNSYDELIKLSLRHRPDLLIVGEIRDKLTAQAVLRASLTGYTVFSTVHASSVRGVIQ
RLSELGLSHWEIKNALSSVVYQRLIAGKGVLDIAKNEFESWSSENWNKKIDQLLTNGYLTPTEAKREKIKTD

Nucleotide

• Length: 939 bp

>NTDB_id=622356 LL047_RS11545 WP_010906320.1 2247503..2248441(-) (comGA) [Lactococcus lactis subsp. lactis strain EIP33]
ATGATACCAAAAATGGCAAAAGAATTAATTCAAAGAGCAATTGATAGAGATGCATCAGATATTTATCTGATTGCTTCAAA
AGAAAAGTATAAACTTTATTTTCGACAAATGACAGCACGTGATCTGGTAGAAGAAATTGGGTTAGAAGTTGGCTTAGCAC
TACTTACTCACTTTAAGTTTCTAGCTGGGATGAATACAGGAGAACGCAGACGAGTTCAATTGGGAGCTTGTTGGTATGAA
ATAGAGGAAAGTAATGCAAAACGTTTGCGTCTTTCGACAGTGGGGGATTTCGAGGGTAATGAATCTTTAGTAATACGTCT
CTTGCATGATCAAAACAAAGAACTTGATTTTTGGTTTGATCAAGAGCTAGAGAATTATGATTGTAAAAGAGGATTGCATC
TCTTTGCCGGTCCAGTAGGCTCGGGAAAAACATCTTTAATGTTTGATTTAGCTCGTCGTCATTTTACAGATTTACAAGTT
ATCAATATAGAAGAACCCGTTGAGTTGATTGATTCCGATTTTATTCAGTTACAAGTCAACGAAGTCATTGGTAATAGTTA
TGATGAATTAATTAAATTATCACTGAGGCATCGCCCAGATTTGTTAATCGTTGGTGAAATTCGTGATAAATTGACCGCTC
AAGCAGTTTTACGGGCTAGTTTGACAGGTTATACAGTGTTTTCAACCGTTCATGCCTCTTCTGTTAGAGGTGTCATTCAG
AGATTATCAGAGCTGGGTTTAAGTCATTGGGAAATAAAAAATGCTTTATCAAGTGTTGTTTATCAGCGTTTAATAGCTGG
GAAAGGAGTATTAGACATTGCCAAAAACGAATTTGAGTCTTGGTCATCAGAAAATTGGAATAAAAAAATTGATCAGCTAC
TTACAAATGGATATCTCACACCTACTGAAGCCAAAAGGGAAAAAATTAAGACTGATTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Lactococcus lactis subsp. cremoris KW2	76.603	100	0.766
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	54.662	99.679	0.545
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	53.055	99.679	0.529
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	52.09	99.679	0.519
comGA/cglA/cilD	Streptococcus pneumoniae D39	52.09	99.679	0.519
comGA/cglA/cilD	Streptococcus pneumoniae R6	52.09	99.679	0.519
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	52.09	99.679	0.519
comYA	Streptococcus gordonii str. Challis substr. CH1	51.923	100	0.519
comYA	Streptococcus mutans UA140	51.923	100	0.519
comYA	Streptococcus mutans UA159	51.923	100	0.519