Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   EKM72_RS13160 Genome accession   NZ_AP019305
Coordinates   2473395..2475203 (+) Length   602 a.a.
NCBI ID   WP_000082725.1    Uniprot ID   A0A2K4AK92
Organism   Staphylococcus aureus strain TUM9458     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2468395..2480203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM72_RS13135 opp4C 2468549..2469430 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  EKM72_RS13140 trpS 2469472..2470461 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  EKM72_RS13145 spxA 2470755..2471150 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  EKM72_RS13150 mecA 2471521..2472240 (+) 720 WP_001217728.1 adaptor protein MecA -
  EKM72_RS13155 coiA 2472361..2473347 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  EKM72_RS13160 pepF 2473395..2475203 (+) 1809 WP_000082725.1 oligoendopeptidase F Regulator
  EKM72_RS13165 yjbH 2475663..2476469 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  EKM72_RS13170 - 2476492..2476857 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  EKM72_RS13175 - 2476961..2477554 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  EKM72_RS13180 - 2477740..2478087 (+) 348 WP_001242103.1 hypothetical protein -
  EKM72_RS13185 - 2478104..2478739 (+) 636 WP_001077683.1 GTP pyrophosphokinase -
  EKM72_RS13190 - 2478756..2479565 (+) 810 WP_001270834.1 NAD kinase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69805.37 Da        Isoelectric Point: 4.9226

>NTDB_id=61565 EKM72_RS13160 WP_000082725.1 2473395..2475203(+) (pepF) [Staphylococcus aureus strain TUM9458]
MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGKEEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYA
HLKQDQDTTNDKYTGMESRAHQLIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRESAFRNVYKAYGAHNNTLGATLAG
EVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLVKTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMP
YEEAKEWMLKALEPMGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVHEFGHSAHS
YFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQELERFRATLFRQTMFAEFEHKIHAIEEAGEP
LTPTRMNEEYAKLNKLYFGDSVETDEDISKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKG
SSNYPIEILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=61565 EKM72_RS13160 WP_000082725.1 2473395..2475203(+) (pepF) [Staphylococcus aureus strain TUM9458]
ATGAGTCAACAATTATCGAGAGAAGAACAGGAACGTAAATATCCTGAATATACATGGGACTTAACAACAATTTTCAAAGA
TGATGAAGCTTTTGAGGCTGCATTTAAAGAAGTTGAAAATGAGTTAGGCAAAGAAGAACAATTTAAAGGACACATTGGTG
ATAGTGCTGAGACATTATACAATGCGTTAGAATTAGAAGATACATTAGGTACTAAATTAGAAAAAGTATATGTATACGCG
CACCTAAAACAAGACCAAGACACAACGAACGACAAGTATACTGGTATGGAGTCAAGAGCACATCAATTAATTATTAAATT
TAGCTCGGCATGGAGTTTCTTAGTGCCAGAGATTTTACAAATTGATGAAGATAAAATTCAATCATTTGTAAATTCATATG
ATAAATTACAAAAATTCGCATTTGATTTGAAGTTGATTAATGAAAAACGTCCTCATATTTTAGATGCTGAAACTGAAAAG
TTATTAACAGAAGCGCAGGACGCGTTATCAACGCCATCAAATGTATACGGTATGTTTAGCAACGCTGATTTAGTATTTGA
AGATGCGATTGATAAAGATGGAAATGCACACCCGTTAACACAAGGTACATTTATTAAGTATTTAGAATCAGATGATCGCA
AACTAAGAGAAAGTGCTTTTAGAAATGTATATAAAGCATATGGTGCTCATAATAATACGCTTGGCGCTACGCTAGCAGGT
GAAGTGAAGAAAAATGTATTTAATGCTCGTACACACAATTACAAAACTGCAAGAGAAAAAGCATTAAGTAATAATCATAT
TCCAGAAAATGTATATGACAATCTAGTAAAAACTGTACATAAATATTTACCATTGCTACATAGATATACTGAATTGCGCA
AAGAATTGCTAGGTTTAGATGACTTGAAAATGTATGATTTATATACACCATTAATTAAAGATATTAAGTTTGAAATGCCT
TATGAAGAAGCTAAAGAGTGGATGTTAAAAGCTTTAGAACCAATGGGTGAAGAATATTTAAATGTAGTTAAAGAAGGCTT
AAACAATCGTTGGGTCGATGTCTATGAGAATAAAGGTAAACGTTCAGGTGGCTATTCATCAGGTGCACATTTAACTAATC
CATTTATTCTACTTAACTGGTCTAATACTATTTCAGACTTATACACATTAGTTCATGAATTTGGGCATTCAGCACATAGT
TACTTCAGTAGAAAATTCCAACCGTCAAATTCTAGTGACTACACTATTTTTGTCGCTGAAGTTGCATCAACTTGTAACGA
AGCACTTTTAAGTGATTATATGGATAAACATCTTGATGATGAAAAACGCTTATTATTATTAAACCAAGAATTAGAACGTT
TCAGAGCTACATTATTCCGACAAACAATGTTCGCAGAATTTGAGCATAAAATTCATGCAATTGAAGAAGCAGGTGAACCA
TTAACGCCAACTAGAATGAATGAAGAATATGCCAAATTAAATAAATTATACTTCGGTGATTCTGTAGAAACTGATGAAGA
TATTAGTAAGGAATGGTCACGTATTCCACACTTCTATATGAATTATTATGTATATCAATACGCAACTGGTTACAGTGCAG
CTCAAAGCTTAAGTCATCAAATTTTAACAGAAGGTAAGCCAGCAGTAGATAGATATATTAATGAATTCTTGAAAAAAGGT
AGCTCAAATTATCCAATTGAGATATTAAAAAATGCTGGTGTAGATATGACAACACCTGAACCAATTGAACAAGCTTGTGA
AGTTTTTGAACAAAAATTGAACGCTTTTGAAAAATTAATGAAAGCTTAG

Domains

Predicted by InterProScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2K4AK92

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

43.952

97.508

0.429

Multiple sequence alignment