Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SII_RS09525 Genome accession   NC_022237
Coordinates   1956051..1957376 (-) Length   441 a.a.
NCBI ID   WP_003075490.1    Uniprot ID   -
Organism   Streptococcus intermedius C270     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1951051..1962376
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SII_RS09505 (SII_1864) - 1952402..1954978 (+) 2577 WP_020999301.1 YfhO family protein -
  SII_RS09520 (SII_1867) comE 1955302..1956051 (-) 750 WP_003075488.1 competence system response regulator transcription factor ComE Regulator
  SII_RS09525 (SII_1868) comD/comD1 1956051..1957376 (-) 1326 WP_003075490.1 GHKL domain-containing protein Regulator
  SII_RS09860 (SII_1869) - 1957393..1957539 (-) 147 WP_003075491.1 bacteriocin -
  SII_RS09540 (SII_1871) rlmH 1957816..1958295 (-) 480 WP_003075603.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SII_RS09545 (SII_1872) htrA 1958499..1959689 (+) 1191 WP_020999302.1 S1C family serine protease Regulator
  SII_RS09550 (SII_1873) spo0J 1959744..1960511 (+) 768 WP_020999303.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 51896.76 Da        Isoelectric Point: 8.7063

>NTDB_id=61566 SII_RS09525 WP_003075490.1 1956051..1957376(-) (comD/comD1) [Streptococcus intermedius C270]
MVKIEFIYWVIFSIIEAISVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTIIHYSVRYIMFFIQPLFFYLYFVKVKKV
KKHSSLFLALFLSLAVSGSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKIDFKENIVQ
LNFYLLFIHLLLNISHWLSNMKNLNSFSSMIATICFLMFMSILFYLQSIREKYEKEEQIKQKEQEQLQLQKYTDEIVNLY
NEIRGFRHDYGGMLASFQSAIHTGDIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIEL
TFEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGAAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGV
GRGLGLSNIKEIINNYEGIILDTKIEDEYFIQAMRVRKEGL

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=61566 SII_RS09525 WP_003075490.1 1956051..1957376(-) (comD/comD1) [Streptococcus intermedius C270]
ATGGTGAAAATAGAATTTATATATTGGGTTATATTCTCCATTATAGAAGCTATTTCTGTTGTATATTGTTATAAGAAGAT
AAGTAGAGTGAATAAAGTGAATATTCACTTTACTTTATTATGTTTAGGAATTGTATTTTTGACTGATTTTACTACAATAA
TACATTATTCGGTTAGATATATAATGTTTTTTATTCAACCATTATTTTTTTATTTATACTTTGTTAAAGTAAAAAAAGTT
AAAAAACATTCGTCTTTATTTTTAGCACTATTTTTATCTTTAGCTGTATCAGGTTCTGAAACCTTCTTTTCAGTTATTAT
TTCTTCTGTTACAGGTGATAAGTTTGTTGATAGATATTGGGGATTGTTCTATATTTTTATTAATATTATTTCTTTAGTTT
TCATTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGATAGATTTTAAAGAAAATATTGTACAA
TTAAATTTTTATCTATTATTTATTCATCTTTTATTAAATATATCGCATTGGCTTAGTAACATGAAAAATTTAAATAGTTT
TTCTAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAATTTTGTTCTACTTACAATCTATTCGCGAAAAATATG
AAAAAGAAGAACAAATTAAGCAAAAAGAACAGGAACAACTGCAATTACAAAAATATACAGATGAAATTGTTAATCTGTAT
AATGAAATTCGAGGTTTTCGTCATGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTGATATAAA
AGAAGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATT
TAAATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTA
ACATTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTCCTTTTAAA
TAATGCGATAGAGGGAGCGGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTAGTAGATCTGGATACAGAAACGATCT
TAGTTATTCAAAATTCACGTAAGAAAAGACCTCTAGATTTGGAAGAAATTTACCAAACTGATTTTTCAACAAAGGGTGTG
GGACGCGGTTTAGGTTTAAGTAATATTAAAGAAATTATTAATAACTATGAAGGAATTATTCTGGATACTAAAATCGAAGA
TGAATATTTTATACAAGCAATGAGAGTAAGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(334-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.795

99.32

0.544
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.299

100

0.544
  comD Streptococcus mitis SK321

46.939

88.889

0.417
  comD Streptococcus mitis NCTC 12261

48.404

85.261

0.413
  comD/comD2 Streptococcus pneumoniae TIGR4

47.872

85.261

0.408
  comD/comD1 Streptococcus pneumoniae Rx1

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae D39

47.34

85.261

0.404
  comD/comD1 Streptococcus pneumoniae R6

47.34

85.261

0.404

Multiple sequence alignment