Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LCH17_RS09280 Genome accession   NZ_CP083944
Coordinates   2042466..2043707 (+) Length   413 a.a.
NCBI ID   WP_011707570.1    Uniprot ID   A0KPV8
Organism   Aeromonas hydrophila strain CSUSB2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2037466..2048707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LCH17_RS09255 (LCH17_09255) ampD 2037830..2038402 (-) 573 WP_171279817.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LCH17_RS09260 (LCH17_09260) - 2038550..2039020 (+) 471 WP_024944772.1 TIGR02281 family clan AA aspartic protease -
  LCH17_RS09265 (LCH17_09265) nadC 2039026..2039883 (+) 858 WP_224481186.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LCH17_RS09270 (LCH17_09270) - 2040206..2040637 (+) 432 WP_041216993.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  LCH17_RS09275 (LCH17_09275) pilB 2040644..2042350 (+) 1707 WP_146061427.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  LCH17_RS09280 (LCH17_09280) pilC 2042466..2043707 (+) 1242 WP_011707570.1 type II secretion system F family protein Machinery gene
  LCH17_RS09285 (LCH17_09285) pilD 2043730..2044602 (+) 873 WP_224481187.1 A24 family peptidase Machinery gene
  LCH17_RS09290 (LCH17_09290) coaE 2044622..2045236 (+) 615 WP_049046581.1 dephospho-CoA kinase -
  LCH17_RS09295 (LCH17_09295) zapD 2045274..2045996 (+) 723 WP_162498668.1 cell division protein ZapD -
  LCH17_RS09300 (LCH17_09300) yacG 2046006..2046200 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  LCH17_RS09305 (LCH17_09305) mutT 2046261..2046674 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  LCH17_RS09310 (LCH17_09310) - 2046683..2047867 (-) 1185 WP_224481188.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45422.58 Da        Isoelectric Point: 9.8637

>NTDB_id=608727 LCH17_RS09280 WP_011707570.1 2042466..2043707(+) (pilC) [Aeromonas hydrophila strain CSUSB2]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGLFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGGIA
LAIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=608727 LCH17_RS09280 WP_011707570.1 2042466..2043707(+) (pilC) [Aeromonas hydrophila strain CSUSB2]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGTGGGGTGAACCGCAAGGGCCA
GAAAGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGTTATTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGCTGTCAGCCGGCGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCAGC
CATGCGCGAGCTCATGGGGCAGATTGCCGCCGATGTGGAGACCGGCACTCCTATGTCCGAGGCGCTGCGCCGCCATCCCC
GTCATTTTGACGATCTCTACTGCGATCTGGTGGAGGCTGGCGAACAGTCCGGCGCTCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCTGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTCTACCCCACCATGGTCATCCTGGT
GGCCATTGTTGTTACCTCCATCCTGCTGCTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCATCTTCACCCAATTCGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATTTTTGGCGGCATAGCG
CTCGCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCGGTGGTTGGCATGATATTGCACAAGGCCGCCATGGCCCGCTTCGCCCGCACCCTCTCCACTACCTTTTCCGCCGGTA
TCCCGCTGGTGGATGCCTTGGTCTCTGCGGCAGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAGCAGGAGGTGGACGATC
TGGTCGACGGCCTCACCAGCCTGCTGGAGCCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGATCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0KPV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

54

96.852

0.523
  pilC Legionella pneumophila strain ERS1305867

51.358

98.063

0.504
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Vibrio cholerae strain A1552

47.739

96.368

0.46
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

37.75

96.852

0.366