Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   K8B68_RS07240 Genome accession   NZ_CP082813
Coordinates   1535315..1535626 (-) Length   103 a.a.
NCBI ID   WP_000472255.1    Uniprot ID   A0A0U1MLR1
Organism   Staphylococcus aureus strain SCAID OTT1-2021 (597/2)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1530315..1540626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B68_RS07205 (K8B68_07205) gcvPA 1530817..1532163 (-) 1347 WP_000019698.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
  K8B68_RS07210 (K8B68_07210) gcvT 1532183..1533274 (-) 1092 WP_000093344.1 glycine cleavage system aminomethyltransferase GcvT -
  K8B68_RS07215 (K8B68_07215) - 1533433..1533957 (-) 525 WP_001015120.1 shikimate kinase -
  K8B68_RS07220 (K8B68_07220) - 1533947..1534093 (-) 147 WP_001789879.1 hypothetical protein -
  K8B68_RS07225 (K8B68_07225) comGF 1534190..1534687 (-) 498 WP_029694423.1 competence type IV pilus minor pilin ComGF Machinery gene
  K8B68_RS07230 (K8B68_07230) comGE 1534623..1534904 (-) 282 WP_000844412.1 hypothetical protein Machinery gene
  K8B68_RS07235 (K8B68_07235) comGD 1534891..1535337 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  K8B68_RS07240 (K8B68_07240) comGC 1535315..1535626 (-) 312 WP_000472255.1 competence type IV pilus major pilin ComGC Machinery gene
  K8B68_RS07245 (K8B68_07245) comGB 1535640..1536710 (-) 1071 WP_000776409.1 competence type IV pilus assembly protein ComGB Machinery gene
  K8B68_RS07250 (K8B68_07250) comGA 1536682..1537656 (-) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  K8B68_RS07255 (K8B68_07255) - 1537708..1538331 (-) 624 WP_001223009.1 MBL fold metallo-hydrolase -
  K8B68_RS07260 (K8B68_07260) - 1538328..1538657 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  K8B68_RS07265 (K8B68_07265) - 1538657..1539643 (-) 987 WP_000161307.1 ROK family glucokinase -
  K8B68_RS07270 (K8B68_07270) - 1539640..1539843 (-) 204 WP_000087561.1 YqgQ family protein -

Sequence

Protein


Download         Length: 103 a.a.        Molecular weight: 11301.33 Da        Isoelectric Point: 8.5268

>NTDB_id=602450 K8B68_RS07240 WP_000472255.1 1535315..1535626(-) (comGC) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGESITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=602450 K8B68_RS07240 WP_000472255.1 1535315..1535626(-) (comGC) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
ATGTTTAAATTTCTAAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGTCAATAACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(6-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1MLR1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus N315

99.029

100

0.99
  comGC Staphylococcus aureus MW2

99.029

100

0.99
  comGC/cglC Streptococcus mitis SK321

47.059

99.029

0.466
  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456
  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456
  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427
  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408
  comYC Streptococcus suis isolate S10

50

75.728

0.379
  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369
  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369