Detailed information NTG0600220

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: K6981_RS14950
• Genome accession: NZ_CP082213
• Coordinates: 3387741..3389000 (+)
• Length: 419 a.a.
• NCBI ID: WP_274396445.1
• Uniprot ID: -
• Organism: Xanthomonas cucurbitae strain WI_206
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	3378575..3389000	3387741..3389000	within	0

Gene organization within MGE regions

Location: 3378575..3389000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6981_RS14915 (K6981_14860)	-	3378575..3378793 (+)	219	WP_274396441.1	hypothetical protein	-
K6981_RS14920 (K6981_14865)	sucD	3378911..3379786 (-)	876	WP_104604276.1	succinate--CoA ligase subunit alpha	-
K6981_RS14925 (K6981_14870)	sucC	3379811..3380980 (-)	1170	WP_274396442.1	ADP-forming succinate--CoA ligase subunit beta	-
K6981_RS14930 (K6981_14875)	-	3381216..3382829 (+)	1614	WP_104604280.1	HAMP domain-containing sensor histidine kinase	-
K6981_RS14935 (K6981_14880)	pilR	3382989..3384380 (+)	1392	WP_170066996.1	sigma-54 dependent transcriptional regulator	Regulator
K6981_RS14940 (K6981_14885)	pilB	3385017..3386726 (-)	1710	WP_274397236.1	type IV-A pilus assembly ATPase PilB	Machinery gene
K6981_RS14945 (K6981_14890)	pilA2	3386969..3387388 (-)	420	WP_274396444.1	pilin	Machinery gene
K6981_RS14950 (K6981_14895)	pilC	3387741..3389000 (+)	1260	WP_274396445.1	type II secretion system F family protein	Machinery gene

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 46001.42 Da
• Isoelectric Point: 10.2301

>NTDB_id=600220 K6981_RS14950 WP_274396445.1 3387741..3389000(+) (pilC) [Xanthomonas cucurbitae strain WI_206]
MSVARSAIKKQPVDRNTSLLQTFVWEGADKRGVKMKGEQTARNANMLRAELRRQGIVPSVVKQKPKPLFGATGKKITAKD
IAFFSRQMATMMKSGVPIVSSLEIIGEGHKNPRMKKMVGQVRTDIEGGSSLYESISKHPVQFDELYRNLVRAGEGAGVLE
TVLDTVATYKENIEALKGKIKKAMFYPAMVVAVAIVVSAILLIFVVPQFEEVFKNFGAELPAFTQLLVNASRFMVSYWWL
MLMVTVGSIVGFIFAYKRSPRMQHALDRLILKVPVIGQIMHNSAIARFARTTAVTFKAGVPLVEALGIVAGATGNKVYEE
AVLRMRDDVSVGYPVNMAMKQVNLFPHMVVQMTAIGEEAGALDTMLFKVADYFEEEVNNAVDALSSLLEPLIMVFIGTIV
GGMVIGMYLPIFKLGAVVG

Nucleotide

• Length: 1260 bp

>NTDB_id=600220 K6981_RS14950 WP_274396445.1 3387741..3389000(+) (pilC) [Xanthomonas cucurbitae strain WI_206]
ATGTCAGTCGCGCGTAGCGCCATCAAGAAGCAACCGGTCGACCGGAACACCAGCCTGCTGCAGACCTTCGTTTGGGAAGG
TGCTGACAAGCGTGGCGTGAAGATGAAGGGAGAGCAAACAGCCCGCAACGCCAATATGTTGCGAGCAGAGCTGCGCCGTC
AGGGCATCGTGCCCAGCGTGGTGAAGCAAAAGCCGAAGCCGCTGTTCGGAGCGACGGGCAAGAAAATTACTGCCAAAGAC
ATTGCGTTCTTCAGCCGTCAGATGGCAACGATGATGAAGTCGGGCGTGCCTATCGTCAGTTCGCTGGAGATCATCGGCGA
GGGACATAAGAACCCACGCATGAAGAAGATGGTCGGCCAGGTCAGGACAGACATTGAGGGGGGATCCTCGCTCTACGAGT
CCATCAGCAAACATCCCGTCCAGTTTGACGAGCTCTACCGCAACCTTGTCCGCGCGGGCGAAGGTGCAGGCGTATTGGAG
ACAGTCCTAGATACGGTCGCCACATACAAAGAAAACATTGAAGCCCTCAAGGGCAAGATCAAAAAGGCGATGTTTTATCC
CGCCATGGTGGTTGCCGTGGCAATCGTTGTAAGTGCGATTTTACTTATCTTCGTGGTACCTCAGTTCGAAGAGGTATTCA
AGAATTTCGGCGCTGAACTACCGGCATTCACCCAGCTTCTCGTCAACGCCTCGCGTTTTATGGTCAGCTATTGGTGGTTG
ATGCTGATGGTGACAGTTGGATCTATCGTTGGCTTCATCTTTGCCTACAAACGTTCTCCACGGATGCAGCATGCACTTGA
TCGATTGATCCTCAAGGTCCCCGTGATTGGGCAGATCATGCACAACAGCGCAATTGCACGTTTTGCGCGGACGACTGCCG
TAACGTTCAAGGCGGGTGTACCTCTCGTCGAGGCACTTGGAATCGTTGCAGGTGCCACCGGCAACAAGGTCTACGAAGAG
GCCGTACTGCGGATGCGCGACGATGTATCGGTCGGCTACCCGGTCAACATGGCGATGAAACAAGTGAATCTGTTTCCGCA
CATGGTGGTGCAGATGACCGCAATTGGCGAAGAAGCAGGCGCCTTGGACACGATGCTGTTCAAGGTAGCTGACTACTTCG
AGGAGGAAGTCAACAACGCCGTGGACGCGCTTAGCAGCCTGCTGGAGCCGCTAATCATGGTGTTCATCGGCACCATCGTA
GGCGGCATGGTCATCGGCATGTATCTTCCGATCTTCAAACTCGGCGCAGTCGTTGGATAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (84-207)

• Type II secretion system (T2SS), protein F (T2SSF) (288-410)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Legionella pneumophila strain ERS1305867	52.956	96.897	0.513
pilC	Pseudomonas stutzeri DSM 10701	54.293	94.511	0.513
pilC	Acinetobacter baylyi ADP1	51.358	96.659	0.496
pilC	Acinetobacter baumannii D1279779	50.123	96.659	0.484
pilG	Neisseria gonorrhoeae MS11	43.358	95.227	0.413
pilG	Neisseria meningitidis 44/76-A	42.857	95.227	0.408
pilC	Vibrio cholerae strain A1552	40.25	95.465	0.384
pilC	Vibrio campbellii strain DS40M4	39	95.465	0.372
pilC	Thermus thermophilus HB27	38.693	94.988	0.368