Detailed information NTG0599956

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: K6972_RS10055
• Genome accession: NZ_CP082203
• Coordinates: 2085693..2086430 (-)
• Length: 245 a.a.
• NCBI ID: WP_105151358.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NJ3
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 2080693..2091430

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6972_RS10035 (K6972_10035)	-	2081686..2082345 (+)	660	WP_002942034.1	metal-dependent transcriptional regulator	-
K6972_RS10040 (K6972_10040)	-	2082754..2083428 (-)	675	WP_222812582.1	CPBP family intramembrane glutamic endopeptidase	-
K6972_RS10045 (K6972_10045)	-	2083754..2084173 (-)	420	WP_029171304.1	hypothetical protein	-
K6972_RS10050 (K6972_10050)	-	2084353..2085693 (-)	1341	WP_222812583.1	GHKL domain-containing protein	-
K6972_RS10055 (K6972_10055)	comE/blpR	2085693..2086430 (-)	738	WP_105151358.1	response regulator transcription factor	Regulator
K6972_RS10060 (K6972_10060)	-	2086648..2086722 (-)	75	WP_232503818.1	hypothetical protein	-
K6972_RS10065 (K6972_10065)	-	2086903..2087088 (-)	186	WP_222812584.1	hypothetical protein	-
K6972_RS10070 (K6972_10070)	dtd	2087154..2087597 (-)	444	WP_024384319.1	D-aminoacyl-tRNA deacylase	-
K6972_RS10075 (K6972_10075)	-	2087599..2089800 (-)	2202	WP_014636726.1	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28368.21 Da
• Isoelectric Point: 5.2226

>NTDB_id=599956 K6972_RS10055 WP_105151358.1 2085693..2086430(-) (comE/blpR) [Streptococcus suis strain NJ3]
MLNIFVLEDDFFQQSRLENAIRRCVEETSVRYKFLEVFGKPNQLLESIEEAGNHQFFFLDIEIKGEEKKGMEIAKEIRAR
DPYAVIVFVTTHSEFMPVTYRYRVSALDFIDKGLEDSDFQKAVSDVLVHAFENIDHTIAENSFVYKTETAHIQVPFSDIL
YFETSSTIHKVILKTKTGQTEFYGKVSDLAKADERLYQAHRSCVVNPLNITKLDRANHIAYFENGDSCFVSRLKQKKLAD
LLEID

Nucleotide

• Length: 738 bp

>NTDB_id=599956 K6972_RS10055 WP_105151358.1 2085693..2086430(-) (comE/blpR) [Streptococcus suis strain NJ3]
ATGCTTAATATTTTTGTATTAGAAGATGATTTTTTTCAGCAGAGTAGGTTAGAAAATGCTATTAGGCGGTGTGTTGAAGA
AACGTCAGTAAGGTATAAATTCTTAGAAGTTTTTGGTAAACCAAATCAATTATTGGAATCAATCGAGGAAGCGGGTAATC
ACCAATTTTTCTTTTTAGATATTGAAATAAAAGGTGAAGAAAAGAAAGGAATGGAAATCGCTAAAGAAATCCGTGCTCGT
GATCCTTATGCTGTTATTGTCTTTGTAACAACTCACTCAGAATTTATGCCGGTAACGTATCGTTATCGGGTTTCTGCTTT
AGATTTTATAGATAAAGGCCTGGAGGATAGTGACTTTCAAAAGGCAGTATCAGATGTCTTAGTGCATGCTTTTGAAAATA
TTGATCATACTATAGCTGAAAATTCTTTTGTATACAAAACTGAAACTGCTCATATTCAAGTCCCTTTTAGTGATATTCTT
TATTTTGAAACATCATCAACGATTCATAAAGTCATTTTAAAAACCAAAACAGGTCAGACTGAATTTTACGGGAAAGTATC
GGATTTAGCGAAAGCTGACGAACGACTTTACCAAGCACATCGTTCTTGTGTAGTGAATCCTTTAAATATAACGAAGTTGG
ACAGAGCAAACCATATTGCCTATTTTGAGAATGGAGATTCTTGTTTTGTTTCTCGTTTGAAGCAGAAGAAACTTGCAGAT
TTGTTGGAGATTGATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-123)

• LytTr DNA-binding domain (LytTR) (152-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.812	97.551	0.535
comE/comE1	Streptococcus equinus JB1	50	97.143	0.486
comE/comE2	Streptococcus equinus JB1	41.152	99.184	0.408
comE	Streptococcus mitis SK321	38.153	100	0.388
comE	Streptococcus pneumoniae R6	38.153	100	0.388
comE	Streptococcus pneumoniae TIGR4	38.153	100	0.388
comE	Streptococcus infantis strain Atu-4	38.153	100	0.388
comE	Streptococcus mitis NCTC 12261	38.153	100	0.388
comE	Streptococcus pneumoniae Rx1	38.153	100	0.388
comE	Streptococcus pneumoniae D39	38.153	100	0.388
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.211	100	0.384
comE/comE2	Streptococcus gordonii strain NCTC7865	38.211	100	0.384