Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   L897_RS00650 Genome accession   NC_021807
Coordinates   103261..104199 (+) Length   312 a.a.
NCBI ID   WP_002993471.1    Uniprot ID   -
Organism   Streptococcus pyogenes HSC5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98261..109199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L897_RS00640 (L897_00665) rpoC 99010..102651 (+) 3642 WP_020833197.1 DNA-directed RNA polymerase subunit beta' -
  L897_RS00645 (L897_00670) - 102803..103168 (+) 366 WP_002986560.1 DUF1033 family protein -
  L897_RS00650 (L897_00675) comYA 103261..104199 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  L897_RS00655 (L897_00680) comYB 104135..105169 (+) 1035 WP_236608388.1 competence type IV pilus assembly protein ComGB Machinery gene
  L897_RS00660 (L897_00685) comYC 105171..105497 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  L897_RS00665 (L897_00690) comGD 105472..105900 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  L897_RS00670 (L897_00695) comGE 105857..106141 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  L897_RS00675 (L897_00700) comYF 106134..106568 (+) 435 WP_020833199.1 competence type IV pilus minor pilin ComGF Machinery gene
  L897_RS00680 (L897_00705) comGG 106552..106878 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  L897_RS00685 (L897_00710) comYH 106976..107929 (+) 954 WP_042361463.1 class I SAM-dependent methyltransferase Machinery gene
  L897_RS00690 (L897_00715) - 107988..109184 (+) 1197 WP_020833201.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35032.27 Da        Isoelectric Point: 8.5799

>NTDB_id=59903 L897_RS00650 WP_002993471.1 103261..104199(+) (comYA) [Streptococcus pyogenes HSC5]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=59903 L897_RS00650 WP_002993471.1 103261..104199(+) (comYA) [Streptococcus pyogenes HSC5]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.679

0.606
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.645

99.359

0.603
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.679

0.596
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.679

0.59
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment