Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   KZB15_RS09280 Genome accession   NZ_CP079922
Coordinates   1835930..1836871 (-) Length   313 a.a.
NCBI ID   WP_000249564.1    Uniprot ID   Q8DN86
Organism   Streptococcus pneumoniae strain R36A     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1830930..1841871
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KZB15_RS09240 (KZB15_09245) comYH 1831416..1832369 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  KZB15_RS09245 (KZB15_09250) - 1832430..1833024 (-) 595 Protein_1830 class I SAM-dependent methyltransferase -
  KZB15_RS09250 (KZB15_09255) comGG/cglG 1833161..1833574 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  KZB15_RS09255 (KZB15_09260) comGF/cglF 1833552..1834013 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  KZB15_RS09260 (KZB15_09265) comGE/cglE 1833976..1834278 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  KZB15_RS09265 (KZB15_09270) comGD/cglD 1834241..1834645 (-) 405 WP_000588026.1 competence type IV pilus minor pilin ComGD Machinery gene
  KZB15_RS09270 (KZB15_09275) comGC/cglC 1834638..1834964 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  KZB15_RS09275 (KZB15_09280) comGB/cglB 1834966..1835982 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  KZB15_RS09280 (KZB15_09285) comGA/cglA/cilD 1835930..1836871 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  KZB15_RS09285 (KZB15_09290) - 1836947..1837312 (-) 366 WP_000286415.1 DUF1033 family protein -
  KZB15_RS09290 (KZB15_09295) - 1837463..1838521 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  KZB15_RS09295 (KZB15_09300) nagA 1838684..1839835 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  KZB15_RS09300 (KZB15_09305) - 1839988..1841805 (-) 1818 WP_001220853.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35555.47 Da        Isoelectric Point: 6.1330

>NTDB_id=590150 KZB15_RS09280 WP_000249564.1 1835930..1836871(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain R36A]
MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDHKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=590150 KZB15_RS09280 WP_000249564.1 1835930..1836871(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain R36A]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCAGCTCGGAAAAAAGGGACGCAGGATATCTATTTTGTCCCTAAGTT
AGACGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCATAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACCTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAGAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DN86

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.