Detailed information NTG0590145

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: KZB15_RS09255
• Genome accession: NZ_CP079922
• Coordinates: 1833552..1834013 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250534.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain R36A
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1828552..1839013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KZB15_RS09225 (KZB15_09230)	-	1828856..1829680 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
KZB15_RS09230 (KZB15_09235)	rnpA	1829655..1830026 (-)	372	WP_000739246.1	ribonuclease P protein component	-
KZB15_RS10715	-	1830043..1830174 (-)	132	WP_000768904.1	hypothetical protein	-
KZB15_RS09235 (KZB15_09240)	-	1830175..1831365 (-)	1191	WP_000167757.1	acetate kinase	-
KZB15_RS09240 (KZB15_09245)	comYH	1831416..1832369 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
KZB15_RS09245 (KZB15_09250)	-	1832430..1833024 (-)	595	Protein_1830	class I SAM-dependent methyltransferase	-
KZB15_RS09250 (KZB15_09255)	comGG/cglG	1833161..1833574 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
KZB15_RS09255 (KZB15_09260)	comGF/cglF	1833552..1834013 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
KZB15_RS09260 (KZB15_09265)	comGE/cglE	1833976..1834278 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
KZB15_RS09265 (KZB15_09270)	comGD/cglD	1834241..1834645 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
KZB15_RS09270 (KZB15_09275)	comGC/cglC	1834638..1834964 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
KZB15_RS09275 (KZB15_09280)	comGB/cglB	1834966..1835982 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
KZB15_RS09280 (KZB15_09285)	comGA/cglA/cilD	1835930..1836871 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
KZB15_RS09285 (KZB15_09290)	-	1836947..1837312 (-)	366	WP_000286415.1	DUF1033 family protein	-
KZB15_RS09290 (KZB15_09295)	-	1837463..1838521 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17972.67 Da
• Isoelectric Point: 9.6092

>NTDB_id=590145 KZB15_RS09255 WP_000250534.1 1833552..1834013(-) (comGF/cglF) [Streptococcus pneumoniae strain R36A]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTNARGRGYQPMVYGLKSVRITEDNQLVRFHFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=590145 KZB15_RS09255 WP_000250534.1 1833552..1834013(-) (comGF/cglF) [Streptococcus pneumoniae strain R36A]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGACTCAAATCTGTACGGATTACAGAGGACAATCAACTGGTTCGCTTTCATT
TCCAGTTCCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	100	100	1
comGF/cglF	Streptococcus pneumoniae D39	100	100	1
comGF/cglF	Streptococcus pneumoniae R6	100	100	1
comGF/cglF	Streptococcus pneumoniae TIGR4	100	100	1
comGF/cglF	Streptococcus mitis SK321	90.85	100	0.909
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895