Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   LPB404_RS00770 Genome accession   NZ_CP079821
Coordinates   173370..174122 (-) Length   250 a.a.
NCBI ID   WP_154856954.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 168370..179122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS00750 (LPB404_00750) - 168662..170284 (+) 1623 WP_023024800.1 ATP-binding cassette domain-containing protein -
  LPB404_RS00755 (LPB404_00755) - 170347..172935 (+) 2589 WP_219074812.1 YfhO family protein -
  LPB404_RS00770 (LPB404_00770) comE/comE2 173370..174122 (-) 753 WP_154856954.1 response regulator transcription factor Regulator
  LPB404_RS09855 - 174123..175442 (-) 1320 WP_257573037.1 GHKL domain-containing protein -
  LPB404_RS00780 (LPB404_00780) - 175442..175585 (-) 144 WP_219074813.1 bacteriocin -
  LPB404_RS00790 (LPB404_00790) rlmH 175948..176427 (-) 480 WP_219074814.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LPB404_RS00795 (LPB404_00795) htrA 176630..177808 (+) 1179 WP_219074815.1 S1C family serine protease Regulator
  LPB404_RS00800 (LPB404_00800) spo0J 177874..178635 (+) 762 WP_219074816.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29453.20 Da        Isoelectric Point: 8.4082

>NTDB_id=589721 LPB404_RS00770 WP_154856954.1 173370..174122(-) (comE/comE2) [Streptococcus rubneri strain LPB0404]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKITELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIVDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVNFDRRKRLLMLEEETTCPVSRTQVKRVE
ELLNKIQKKA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=589721 LPB404_RS00770 WP_154856954.1 173370..174122(-) (comE/comE2) [Streptococcus rubneri strain LPB0404]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTGAAAGCTATCGCTGAGGAGGA
AGGTCTACGATTAAATATTGTTTCCACCAGTAAAATAACTGAACTGAAGGAGTATCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTTGATATTGATATCAAAGGGGATGAAAAAGCTGGTATCAAGGCAGCTCAAATGATTCGTGAGGTCAATCCT
TTTGCGATCATTGCCTTTATCACGACGAAATCGGAATTTGCTACCATTACCTATCGTTACAAGGTATCAGCTCTTGAATT
TATTGAGAAAACCTTGAATGAAAACTTGTTTAAAGAAAAAATTCGAGAGTGTATTCTCTACTTAAAGAAAAATGTGATTG
AAAATAAAAATATCGTTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTTCCATATCGAGATATATTGTAC
ATTGAGACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTCGACAATCATTTCTTTAGTCCCAATCAGTCTTATCTAGTCAATCAAAGAATGATTGTCAATT
TTGATCGTCGCAAGAGACTCTTGATGTTAGAAGAGGAGACAACTTGCCCTGTCTCTCGTACACAGGTGAAAAGGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-243)

Response regulator receiver domain (Response_reg)

(18-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

50.4

100

0.504
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

50.4

100

0.504
  comE Streptococcus infantis strain Atu-4

49.2

100

0.492
  comE Streptococcus mitis SK321

48

100

0.48
  comE Streptococcus mitis NCTC 12261

48

100

0.48
  comE Streptococcus pneumoniae Rx1

47.2

100

0.472
  comE Streptococcus pneumoniae D39

47.2

100

0.472
  comE Streptococcus pneumoniae R6

47.2

100

0.472
  comE Streptococcus pneumoniae TIGR4

47.2

100

0.472
  comE/comE1 Streptococcus equinus JB1

37.805

98.4

0.372