Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   LPB404_RS00795 Genome accession   NZ_CP079821
Coordinates   176630..177808 (+) Length   392 a.a.
NCBI ID   WP_219074815.1    Uniprot ID   -
Organism   Streptococcus rubneri strain LPB0404     
Function   degrading CSP; selective degradation of ComEA and ComEC (predicted from homology)   
Competence regulation

Genomic Context

Location: 171630..182808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB404_RS00770 (LPB404_00770) comE/comE2 173370..174122 (-) 753 WP_154856954.1 response regulator transcription factor Regulator
  LPB404_RS09855 - 174123..175442 (-) 1320 WP_257573037.1 GHKL domain-containing protein -
  LPB404_RS00780 (LPB404_00780) - 175442..175585 (-) 144 WP_219074813.1 bacteriocin -
  LPB404_RS00790 (LPB404_00790) rlmH 175948..176427 (-) 480 WP_219074814.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LPB404_RS00795 (LPB404_00795) htrA 176630..177808 (+) 1179 WP_219074815.1 S1C family serine protease Regulator
  LPB404_RS00800 (LPB404_00800) spo0J 177874..178635 (+) 762 WP_219074816.1 ParB/RepB/Spo0J family partition protein Regulator
  LPB404_RS00805 (LPB404_00805) dnaA 178914..180254 (+) 1341 WP_374030896.1 chromosomal replication initiator protein DnaA -
  LPB404_RS00810 (LPB404_00810) dnaN 180415..181551 (+) 1137 WP_006595327.1 DNA polymerase III subunit beta -
  LPB404_RS00815 (LPB404_00815) - 181615..181806 (+) 192 WP_061564542.1 DUF951 domain-containing protein -
  LPB404_RS00820 (LPB404_00820) - 181994..182488 (-) 495 WP_125374716.1 DUF1307 domain-containing protein -

Sequence

Protein


Download         Length: 392 a.a.        Molecular weight: 41297.62 Da        Isoelectric Point: 5.7942

>NTDB_id=589722 LPB404_RS00795 WP_219074815.1 176630..177808(+) (htrA) [Streptococcus rubneri strain LPB0404]
MKQSSNFLKKALQLLLVLVIGFTGGILGTLTSFQFTKGNSANSSQEIKSTKVNRAYKNTTSTSEAVDKVKNAVVSVITYA
ETSEKGFINGETDSDPEVASEGSGVIYKKDGKDAYVVTNAHVLMGATQADILFADGNKVSGEVVGSDTFSDIAVVKISSD
NVTTVAEFGDSSKLTVGETAIAIGSPLGTKFANSVTQGIVSSLGRTVKLKSEDGQNVSTKALQTDAAINPGNSGGPLINI
QGQVIGITSSKISSNGQTAVEGMGFAIPVNDVQNIIEHLEKDGKVIRPALGITMMDLANLSSSDLSQLDIPSKLKGGVLV
RSVENDMPASKHLRRLDIITKIDDTTIESTADLQSALYSHQIGDKIKVIFYRDGKQKTATIELTKSTENLGN

Nucleotide


Download         Length: 1179 bp        

>NTDB_id=589722 LPB404_RS00795 WP_219074815.1 176630..177808(+) (htrA) [Streptococcus rubneri strain LPB0404]
ATGAAACAATCATCAAATTTTCTAAAAAAAGCTTTGCAACTTTTACTTGTTCTTGTCATTGGTTTTACTGGAGGAATCTT
AGGAACCTTAACCTCTTTCCAGTTTACCAAAGGGAATTCTGCAAATTCTAGCCAAGAAATAAAATCTACCAAAGTTAATC
GTGCTTATAAGAATACAACATCAACTAGTGAAGCTGTTGATAAGGTAAAAAATGCGGTTGTTTCTGTTATTACATACGCT
GAAACCTCTGAAAAAGGCTTCATCAATGGAGAAACAGATTCTGATCCAGAAGTGGCTAGTGAAGGTTCAGGTGTTATCTA
TAAAAAAGATGGTAAGGATGCTTATGTAGTAACCAATGCTCACGTGTTAATGGGAGCAACACAAGCCGACATTCTTTTTG
CAGATGGAAACAAAGTTTCTGGAGAAGTTGTTGGTTCAGATACTTTCTCAGATATTGCGGTTGTCAAAATCAGTTCAGAT
AACGTTACGACCGTGGCTGAATTTGGGGATTCCTCTAAATTGACCGTCGGAGAAACTGCAATCGCTATTGGTAGTCCTTT
AGGGACAAAATTTGCCAATTCCGTTACCCAAGGGATTGTTTCTAGTCTCGGACGTACTGTGAAGCTCAAATCAGAAGACG
GTCAAAATGTGTCTACAAAAGCTTTGCAAACAGATGCTGCAATCAACCCAGGGAATTCTGGTGGTCCCCTTATCAATATT
CAGGGACAAGTCATCGGAATTACCTCAAGTAAAATCTCTTCAAATGGGCAAACTGCGGTTGAAGGAATGGGATTTGCTAT
TCCTGTAAATGATGTACAAAATATTATTGAACATTTAGAAAAAGATGGTAAAGTAATCCGTCCAGCACTTGGGATTACCA
TGATGGACTTGGCTAACCTATCCTCTTCTGATCTTAGCCAATTAGACATTCCAAGCAAACTCAAAGGTGGGGTTCTTGTC
CGCTCAGTTGAAAATGATATGCCAGCATCCAAACATTTACGTCGACTAGATATCATTACAAAAATCGATGATACAACCAT
TGAATCAACTGCGGATTTACAATCTGCCCTCTATTCTCATCAAATTGGTGATAAAATAAAAGTCATTTTCTACAGAGATG
GTAAGCAAAAAACAGCAACCATTGAACTAACAAAATCTACAGAAAATCTTGGAAATTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(288-383)

Trypsin-like peptidase domain (Trypsin_2)

(102-247)

Peptidase family M50 (Peptidase_M50)

(233-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus pneumoniae R6

63.265

100

0.633
  htrA Streptococcus pneumoniae Rx1

63.265

100

0.633
  htrA Streptococcus pneumoniae D39

63.265

100

0.633
  htrA Streptococcus pneumoniae TIGR4

63.265

100

0.633
  htrA Streptococcus mitis NCTC 12261

63.01

100

0.63
  htrA Streptococcus gordonii str. Challis substr. CH1

62.437

100

0.628
  htrA Streptococcus mutans UA159

52.25

100

0.533