Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   KVP03_RS02155 Genome accession   NZ_CP077959
Coordinates   429823..430761 (+) Length   312 a.a.
NCBI ID   WP_230923172.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ_14-145     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 424823..435761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KVP03_RS02135 (KVP03_02130) - 425182..426414 (+) 1233 WP_014622136.1 hypothetical protein -
  KVP03_RS02140 (KVP03_02135) - 426734..426925 (+) 192 Protein_361 lactococcin 972 family bacteriocin -
  KVP03_RS02145 (KVP03_02140) - 426990..428993 (+) 2004 WP_111692093.1 DUF1430 domain-containing protein -
  KVP03_RS02150 (KVP03_02145) - 428995..429642 (+) 648 WP_111692094.1 ABC transporter ATP-binding protein -
  KVP03_RS02155 (KVP03_02150) comGA/cglA 429823..430761 (+) 939 WP_230923172.1 competence type IV pilus ATPase ComGA Machinery gene
  KVP03_RS02160 (KVP03_02155) comYB 430694..431728 (+) 1035 WP_227687788.1 competence type IV pilus assembly protein ComGB Machinery gene
  KVP03_RS02165 (KVP03_02160) comGC/cglC 431729..432052 (+) 324 WP_012514782.1 competence type IV pilus major pilin ComGC Machinery gene
  KVP03_RS02170 (KVP03_02165) comGD 432030..432455 (+) 426 WP_012514783.1 competence type IV pilus minor pilin ComGD -
  KVP03_RS02175 (KVP03_02170) comGE 432460..432702 (+) 243 WP_012677236.1 competence type IV pilus minor pilin ComGE -
  KVP03_RS02180 (KVP03_02175) comYF 432689..433123 (+) 435 WP_037580631.1 competence type IV pilus minor pilin ComGF Machinery gene
  KVP03_RS02185 (KVP03_02180) comGG 433101..433463 (+) 363 WP_012514785.1 competence type IV pilus minor pilin ComGG -
  KVP03_RS02190 (KVP03_02185) - 433531..434873 (+) 1343 WP_195759329.1 IS3 family transposase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35169.35 Da        Isoelectric Point: 6.6904

>NTDB_id=585639 KVP03_RS02155 WP_230923172.1 429823..430761(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLIDVCESDRMANLISHFKFIAGMNVGEKRRCQLGACDYD
LDGAKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQKEFEHHQASQWNQQIDQLLAEGHLNTGQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=585639 KVP03_RS02155 WP_230923172.1 429823..430761(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGATTCAAGAATTAGCCAAGCGGCTTATCAGGCAGGCTGAAGAATTGCAGGCTCAGGATATTTATATACTACCAAGGGG
GACAGGCTATGAGCTTTTGATGAGGGTAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCATTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGCCAGCTCGGTGCTTGTGACTACGAC
CTTGATGGCGCTAAGGTATCTCTACGATTATCAGCTGTGGGTGACTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCCAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATCAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTAACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGCGTTTAC
GCTAGGCTGCTAGAATTAGGCATTTCAAGGGCAGAATTGGATAATAGTCTAGCAATGGTTGCTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCGCAAAAGGAATTTGAACATCATCAAGCCAGCCAGTGGAATCAGCAGATTGATCAGC
TTCTTGCGGAGGGACATCTCAATACCGGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA159

63.023

99.679

0.628
  comYA Streptococcus mutans UA140

63.023

99.679

0.628
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.968

99.359

0.606
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.968

99.359

0.606
  comYA Streptococcus gordonii str. Challis substr. CH1

60.968

99.359

0.606
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.968

99.359

0.606
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.968

99.359

0.606
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

39.796

94.231

0.375