Detailed information NTG0585641

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: KVP03_RS02165
• Genome accession: NZ_CP077959
• Coordinates: 431729..432052 (+)
• Length: 107 a.a.
• NCBI ID: WP_012514782.1
• Uniprot ID: B4U056
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ_14-145
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 426729..437052

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KVP03_RS02140 (KVP03_02135)	-	426734..426925 (+)	192	Protein_361	lactococcin 972 family bacteriocin	-
KVP03_RS02145 (KVP03_02140)	-	426990..428993 (+)	2004	WP_111692093.1	DUF1430 domain-containing protein	-
KVP03_RS02150 (KVP03_02145)	-	428995..429642 (+)	648	WP_111692094.1	ABC transporter ATP-binding protein	-
KVP03_RS02155 (KVP03_02150)	comGA/cglA	429823..430761 (+)	939	WP_230923172.1	competence type IV pilus ATPase ComGA	Machinery gene
KVP03_RS02160 (KVP03_02155)	comYB	430694..431728 (+)	1035	WP_227687788.1	competence type IV pilus assembly protein ComGB	Machinery gene
KVP03_RS02165 (KVP03_02160)	comGC/cglC	431729..432052 (+)	324	WP_012514782.1	competence type IV pilus major pilin ComGC	Machinery gene
KVP03_RS02170 (KVP03_02165)	comGD	432030..432455 (+)	426	WP_012514783.1	competence type IV pilus minor pilin ComGD	-
KVP03_RS02175 (KVP03_02170)	comGE	432460..432702 (+)	243	WP_012677236.1	competence type IV pilus minor pilin ComGE	-
KVP03_RS02180 (KVP03_02175)	comYF	432689..433123 (+)	435	WP_037580631.1	competence type IV pilus minor pilin ComGF	Machinery gene
KVP03_RS02185 (KVP03_02180)	comGG	433101..433463 (+)	363	WP_012514785.1	competence type IV pilus minor pilin ComGG	-
KVP03_RS02190 (KVP03_02185)	-	433531..434873 (+)	1343	WP_195759329.1	IS3 family transposase	-
KVP03_RS02195 (KVP03_02190)	comYH	434957..435910 (+)	954	WP_154298646.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12149.19 Da
• Isoelectric Point: 8.4057

>NTDB_id=585641 KVP03_RS02165 WP_012514782.1 431729..432052(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKDKVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQE
DGSISDKQQKAYQDYYAKHKDEAKKLN

Nucleotide

• Length: 324 bp

>NTDB_id=585641 KVP03_RS02165 WP_012514782.1 431729..432052(+) (comGC/cglC) [Streptococcus equi subsp. zooepidemicus strain SEZ_14-145]
ATGAAAATGAGATTATCAATCTTAAAAGATCAAGGTGTTCAGGCCTTCACTTTACTGGAAATGCTTCTGGTTTTGTTAAT
CATTAGTGTTTTGATGCTGTTATTTGTTCCAAATTTAAGTAAGCAAAAGGATAAGGTGACAGACACAGGCAATGCTGCGG
TGGTAAAGCTGGTTGAAAATCAGGCAGAGCTTTATGAATTATCACATGGGGAAAAGCCAAGCCTGAAGCAGCTGCAAGAG
GATGGAAGCATCAGTGACAAGCAACAAAAGGCTTATCAGGATTATTATGCAAAGCATAAAGATGAAGCTAAGAAGCTCAA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: B4U056

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	59.813	100	0.598
comGC/cglC	Streptococcus pneumoniae Rx1	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae D39	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae R6	57.944	100	0.579
comGC/cglC	Streptococcus pneumoniae TIGR4	57.944	100	0.579
comYC	Streptococcus gordonii str. Challis substr. CH1	62.245	91.589	0.57
comGC/cglC	Streptococcus mitis NCTC 12261	61.616	92.523	0.57
comYC	Streptococcus mutans UA140	58.763	90.654	0.533
comYC	Streptococcus mutans UA159	58.763	90.654	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	56.842	88.785	0.505
comYC	Streptococcus suis isolate S10	60	74.766	0.449
comGC	Staphylococcus aureus MW2	50	72.897	0.364
comGC	Staphylococcus aureus N315	50	72.897	0.364