Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   KU506_RS11780 Genome accession   NZ_CP077868
Coordinates   2399139..2399708 (-) Length   189 a.a.
NCBI ID   WP_000872872.1    Uniprot ID   A0AB73JJN0
Organism   Staphylococcus aureus strain 366     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2394139..2404708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KU506_RS11740 (KU506_11700) - 2394613..2395221 (-) 609 WP_000020296.1 class I SAM-dependent methyltransferase -
  KU506_RS11745 (KU506_11705) rplL 2395396..2395764 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  KU506_RS11750 (KU506_11710) rplJ 2395807..2396307 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  KU506_RS11755 (KU506_11715) rplA 2396579..2397271 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  KU506_RS11760 (KU506_11720) rplK 2397479..2397901 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  KU506_RS11765 (KU506_11725) nusG 2398082..2398630 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  KU506_RS11770 (KU506_11730) secE 2398643..2398825 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  KU506_RS11775 (KU506_11735) rpmG 2398881..2399024 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  KU506_RS11780 (KU506_11740) sigH 2399139..2399708 (-) 570 WP_000872872.1 sigma-70 family RNA polymerase sigma factor Regulator
  KU506_RS11785 (KU506_11745) - 2399789..2400313 (-) 525 WP_000664738.1 NYN domain-containing protein -
  KU506_RS11790 (KU506_11750) rlmB 2400313..2401059 (-) 747 WP_000390339.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  KU506_RS11795 (KU506_11755) - 2401067..2401471 (-) 405 WP_000370186.1 Mini-ribonuclease 3 -
  KU506_RS11800 (KU506_11760) cysS 2401464..2402864 (-) 1401 WP_000631977.1 cysteine--tRNA ligase -
  KU506_RS11805 (KU506_11765) cysE 2402848..2403495 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23079.92 Da        Isoelectric Point: 9.6015

>NTDB_id=584294 KU506_RS11780 WP_000872872.1 2399139..2399708(-) (sigH) [Staphylococcus aureus strain 366]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRIDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=584294 KU506_RS11780 WP_000872872.1 2399139..2399708(-) (sigH) [Staphylococcus aureus strain 366]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATAGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979