Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   I6L47_RS11465 Genome accession   NZ_CP077221
Coordinates   2538659..2539900 (+) Length   413 a.a.
NCBI ID   WP_005336136.1    Uniprot ID   A0A0T6QCE0
Organism   Aeromonas sp. FDAARGOS 1417     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2533659..2544900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L47_RS11440 (I6L47_11440) ampD 2533847..2534422 (-) 576 WP_139440264.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  I6L47_RS11445 (I6L47_11445) - 2534553..2535023 (+) 471 WP_040068932.1 TIGR02281 family clan AA aspartic protease -
  I6L47_RS11450 (I6L47_11450) nadC 2535027..2535902 (+) 876 WP_216947458.1 carboxylating nicotinate-nucleotide diphosphorylase -
  I6L47_RS11455 (I6L47_11455) tapA 2536230..2536709 (+) 480 WP_216949346.1 type IVa pilus major pilin TapA -
  I6L47_RS11460 (I6L47_11460) pilB 2536713..2538419 (+) 1707 WP_005336134.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  I6L47_RS11465 (I6L47_11465) pilC 2538659..2539900 (+) 1242 WP_005336136.1 type II secretion system F family protein Machinery gene
  I6L47_RS11470 (I6L47_11470) pilD 2539962..2540834 (+) 873 WP_216947459.1 A24 family peptidase Machinery gene
  I6L47_RS11475 (I6L47_11475) coaE 2540848..2541462 (+) 615 WP_216947460.1 dephospho-CoA kinase -
  I6L47_RS11480 (I6L47_11480) zapD 2541500..2542222 (+) 723 WP_216947461.1 cell division protein ZapD -
  I6L47_RS11485 (I6L47_11485) yacG 2542232..2542426 (+) 195 WP_005336142.1 DNA gyrase inhibitor YacG -
  I6L47_RS11490 (I6L47_11490) mutT 2542504..2542908 (-) 405 WP_019444787.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45427.55 Da        Isoelectric Point: 9.7221

>NTDB_id=579948 I6L47_RS11465 WP_005336136.1 2538659..2539900(+) (pilC) [Aeromonas sp. FDAARGOS 1417]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=579948 I6L47_RS11465 WP_005336136.1 2538659..2539900(+) (pilC) [Aeromonas sp. FDAARGOS 1417]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCCGATAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTGGCCAAGAAATCCCAAGGGCTCTTCTCCAAGGGCGGCGCGAAGATCAAACCGATGGATATCGCCATCGTCTCCCGT
CAGATCACCACCATGCTCTCCGCCGGTGTACCACTGGTGCAGAGCCTGCAGATTATCGCCCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCGGAAGCGCTGCGTCGCCATCCTC
TCTATTTCGATGATCTCTACTGCGATCTGGTGGAAGCCGGTGAGCAATCCGGTGCACTGGAGACCATCTACGACCGTATC
GCCACTTACCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCAATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATCGTGGTCACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTCGGCGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACGGCC
CTTGGCATCTTCCTTTACGTGCGGGCCTGGCGGGCCTCCCAGAAAGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCCCGCTTTGCCCGTACTCTGTCGACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCGCTGATTTCGGCGGCAGGGGCCTCCGGCAACTATGTCTATCGCACCGCGGTCATGGCGATCCGC
AACGAGGTGGTGGCAGGCATGCAGATCAACGTGGCGATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAGGAGTCCGGCGCCATCGATGATATGCTCTCCAAGGTAGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATCGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGACGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T6QCE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368