Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   I6L49_RS17890 Genome accession   NZ_CP077209
Coordinates   3907813..3909054 (-) Length   413 a.a.
NCBI ID   WP_005336136.1    Uniprot ID   A0A0T6QCE0
Organism   Aeromonas sp. FDAARGOS 1419     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3902813..3914054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L49_RS17865 (I6L49_17865) mutT 3904805..3905209 (+) 405 WP_042053534.1 8-oxo-dGTP diphosphatase MutT -
  I6L49_RS17870 (I6L49_17870) yacG 3905287..3905481 (-) 195 WP_216950045.1 DNA gyrase inhibitor YacG -
  I6L49_RS17875 (I6L49_17875) zapD 3905491..3906213 (-) 723 WP_005336141.1 cell division protein ZapD -
  I6L49_RS17880 (I6L49_17880) coaE 3906251..3906865 (-) 615 WP_019444785.1 dephospho-CoA kinase -
  I6L49_RS17885 (I6L49_17885) pilD 3906879..3907751 (-) 873 WP_216950046.1 A24 family peptidase Machinery gene
  I6L49_RS17890 (I6L49_17890) pilC 3907813..3909054 (-) 1242 WP_005336136.1 type II secretion system F family protein Machinery gene
  I6L49_RS17895 (I6L49_17895) pilB 3909295..3911001 (-) 1707 WP_005356616.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  I6L49_RS17900 (I6L49_17900) - 3911004..3911447 (-) 444 WP_216950047.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  I6L49_RS17905 (I6L49_17905) nadC 3911763..3912626 (-) 864 WP_216950048.1 carboxylating nicotinate-nucleotide diphosphorylase -
  I6L49_RS17910 (I6L49_17910) - 3912630..3913100 (-) 471 WP_216950049.1 TIGR02281 family clan AA aspartic protease -
  I6L49_RS17915 (I6L49_17915) ampD 3913231..3913806 (+) 576 WP_069554218.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45427.55 Da        Isoelectric Point: 9.7221

>NTDB_id=579850 I6L49_RS17890 WP_005336136.1 3907813..3909054(-) (pilC) [Aeromonas sp. FDAARGOS 1419]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=579850 I6L49_RS17890 WP_005336136.1 3907813..3909054(-) (pilC) [Aeromonas sp. FDAARGOS 1419]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTTAATCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCTGACAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTGGCCAAGAAATCCCAGGGGCTTTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCCCGC
CAAATAACTACCATGCTCTCCGCCGGCGTACCACTGGTGCAGAGCCTGCAGATCATCGCCCGCAGTCACGAGAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCGGAGGCGCTGCGCCGCCATCCCC
TCTACTTTGACGATCTCTACTGCGATCTGGTTGAAGCCGGTGAGCAATCCGGTGCGCTGGAGACCATCTACGACCGTATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATCGTGGTGACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTTGGTGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACGGCC
CTTGGCATCTTCCTCTATGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCCCGCTTTGCCCGCACCCTGTCTACCACCTTCTCCGCCGGTA
TCCCGCTGGTGGATGCGCTGATTTCGGCGGCTGGCGCCTCCGGCAACTATGTCTATCGCACCGCGGTCATGGCCATCCGC
AACGAGGTGGTGGCGGGCATGCAGATCAACGTGGCGATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAGGAGTCCGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGACT
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATCGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGACGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T6QCE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368