Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   KQ224_RS06220 Genome accession   NZ_CP076721
Coordinates   1214188..1214925 (-) Length   245 a.a.
NCBI ID   WP_216806235.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1209188..1219925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS06175 (KQ224_06175) - 1210035..1210229 (-) 195 WP_216806229.1 hypothetical protein -
  KQ224_RS06180 (KQ224_06180) - 1210257..1210448 (-) 192 WP_029176447.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KQ224_RS06185 (KQ224_06185) - 1210469..1210657 (-) 189 WP_216806230.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  KQ224_RS06190 (KQ224_06190) - 1210836..1210961 (-) 126 WP_105129977.1 bacteriocin -
  KQ224_RS06195 (KQ224_06195) - 1210972..1211115 (-) 144 WP_153048551.1 bacteriocin -
  KQ224_RS06200 (KQ224_06200) - 1211451..1211588 (-) 138 WP_216806231.1 hypothetical protein -
  KQ224_RS06205 (KQ224_06205) - 1211601..1212389 (-) 789 WP_216806232.1 ParA family protein -
  KQ224_RS11700 (KQ224_06210) - 1212591..1212716 (+) 126 WP_216806233.1 bacteriocin -
  KQ224_RS06215 (KQ224_06215) - 1212845..1214188 (-) 1344 WP_216806234.1 sensor histidine kinase -
  KQ224_RS06220 (KQ224_06220) comE/blpR 1214188..1214925 (-) 738 WP_216806235.1 response regulator transcription factor Regulator
  KQ224_RS11705 - 1215787..1215972 (-) 186 WP_024391547.1 hypothetical protein -
  KQ224_RS06225 (KQ224_06225) dtd 1216049..1216492 (-) 444 WP_130554438.1 D-aminoacyl-tRNA deacylase -
  KQ224_RS06230 (KQ224_06230) - 1216494..1218698 (-) 2205 WP_216806236.1 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase -
  KQ224_RS06235 (KQ224_06235) - 1218809..1219345 (+) 537 WP_216806237.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28445.30 Da        Isoelectric Point: 5.0849

>NTDB_id=577581 KQ224_RS06220 WP_216806235.1 1214188..1214925(-) (comE/blpR) [Streptococcus parasuis strain H35]
MLNIFVLEDDFFQQSRLENAIRRCVEETSVRYKFLEVFGKPNQLLESIEEAGNHQFFFLDIEIKGEEKKGMEIAKEIRAR
DPYAVIVFVTTHSEFMPVTYRYRVSALDFIDKGLEDSDFQKAVSDVLVHAFENIDHTIAENSFIYKTETAHIQVPFSDIL
YFETSSTIHKVILKTKTGQTEFYGKVSDIAKADERLYQAHRSCVVNPLNITRLDRTNQIAYFENGESCFVSRLKQKKLAD
LLEID

Nucleotide


Download         Length: 738 bp        

>NTDB_id=577581 KQ224_RS06220 WP_216806235.1 1214188..1214925(-) (comE/blpR) [Streptococcus parasuis strain H35]
ATGCTTAATATTTTTGTATTAGAAGATGATTTTTTTCAGCAGAGCAGGCTAGAAAATGCTATTAGGCGGTGTGTTGAAGA
AACGTCAGTAAGGTATAAATTCCTAGAAGTTTTTGGTAAACCAAATCAGTTATTGGAATCAATTGAGGAAGCAGGCAATC
ACCAATTTTTCTTTTTAGATATTGAAATTAAAGGCGAAGAAAAGAAAGGAATGGAAATCGCTAAAGAAATCCGTGCTCGC
GATCCCTATGCTGTTATTGTCTTTGTAACAACTCACTCAGAATTTATGCCGGTAACGTATCGTTATCGAGTTTCTGCTTT
AGATTTTATAGATAAAGGCCTAGAGGATAGTGACTTTCAAAAGGCAGTATCAGATGTGTTAGTGCATGCTTTTGAAAATA
TTGATCATACTATAGCTGAAAATTCTTTTATATATAAAACTGAAACTGCTCATATTCAAGTCCCTTTTAGTGATATTCTT
TATTTTGAAACATCATCAACGATTCATAAAGTCATTTTAAAAACGAAAACAGGTCAGACTGAGTTTTACGGGAAAGTATC
CGATATAGCGAAAGCTGACGAACGACTTTACCAGGCACATCGTTCTTGTGTAGTGAATCCATTAAATATAACAAGATTGG
ACAGAACAAACCAGATTGCCTATTTTGAGAATGGAGAATCTTGTTTTGTTTCTCGTTTGAAGCAGAAGAAACTTGCAGAT
TTGCTGGAGATTGATTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-242)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

56.067

97.551

0.547
  comE/comE1 Streptococcus equinus JB1

50

97.143

0.486
  comE/comE2 Streptococcus equinus JB1

41.152

99.184

0.408
  comE Streptococcus pneumoniae TIGR4

38.8

100

0.396
  comE Streptococcus pneumoniae Rx1

38.8

100

0.396
  comE Streptococcus pneumoniae D39

38.8

100

0.396
  comE Streptococcus pneumoniae R6

38.8

100

0.396
  comE Streptococcus mitis NCTC 12261

38.8

100

0.396
  comE Streptococcus mitis SK321

38.8

100

0.396
  comE Streptococcus infantis strain Atu-4

38.554

100

0.392
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.618

100

0.388
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.618

100

0.388