Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   INT76_RS06940 Genome accession   NZ_CP073084
Coordinates   1346166..1347347 (-) Length   393 a.a.
NCBI ID   WP_212569766.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1341166..1352347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS06905 (INT76_06905) comR 1341215..1342114 (-) 900 WP_212569759.1 XRE family transcriptional regulator Regulator
  INT76_RS06910 (INT76_06910) - 1342339..1343103 (+) 765 WP_212569760.1 DpnI domain-containing protein -
  INT76_RS06915 (INT76_06915) - 1343189..1343509 (-) 321 WP_212569761.1 DUF1292 domain-containing protein -
  INT76_RS06920 (INT76_06920) ruvX 1343520..1343939 (-) 420 WP_212569762.1 Holliday junction resolvase RuvX -
  INT76_RS06925 (INT76_06925) - 1343939..1344205 (-) 267 WP_212569763.1 IreB family regulatory phosphoprotein -
  INT76_RS06930 (INT76_06930) spx 1344321..1344719 (-) 399 WP_212569764.1 transcriptional regulator Spx -
  INT76_RS06935 (INT76_06935) recA 1344971..1346110 (-) 1140 WP_212569765.1 recombinase RecA Machinery gene
  INT76_RS06940 (INT76_06940) cinA 1346166..1347347 (-) 1182 WP_212569766.1 competence/damage-inducible protein A Machinery gene
  INT76_RS06945 (INT76_06945) - 1347492..1348157 (-) 666 WP_212569767.1 type II CAAX endopeptidase family protein -
  INT76_RS06950 (INT76_06950) - 1348130..1348540 (-) 411 WP_212569768.1 helix-turn-helix transcriptional regulator -
  INT76_RS06955 (INT76_06955) - 1348614..1349174 (-) 561 WP_212569769.1 DNA-3-methyladenine glycosylase I -
  INT76_RS06960 (INT76_06960) ruvA 1349185..1349775 (-) 591 WP_212569770.1 Holliday junction branch migration protein RuvA -
  INT76_RS06965 (INT76_06965) mutL 1349822..1351738 (-) 1917 WP_212569771.1 DNA mismatch repair endonuclease MutL -
  INT76_RS06970 (INT76_06970) - 1351818..1352126 (-) 309 WP_212569772.1 DUF898 family protein -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42525.31 Da        Isoelectric Point: 4.7393

>NTDB_id=557857 INT76_RS06940 WP_212569766.1 1346166..1347347(-) (cinA) [Streptococcus oriscaviae strain HKU75]
MKAELIAVGTEILTGQIVNTNAQFLSEKFAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LARFLGRELVFDSLAMERLNRFFASRPGRVRTANNERQAQIIAGSQALQNPTGLAVGGLIEQDGVTYVVLPGPPGELKSM
FAQSLLPLIGQSNQQLYSRVLRFFGIGESQLVTILADMIENQTDPTLAPYAKTGEVTLRLSTKSTSSRQATAKLDQLEAE
ILSHANLSDLLYGYGEDNSLAQVVAQSLGEQQQSIAVVENLTAGLLQADLTLALQDRQLYKGGQILTNSEANLELAGKEA
ERIRQLHQTDKGLAVLGTFNPRSQADNVMATFYLATASLDGIITEEVALGGYSWPAIRQIACMNALDHVRKTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=557857 INT76_RS06940 WP_212569766.1 1346166..1347347(-) (cinA) [Streptococcus oriscaviae strain HKU75]
ATGAAAGCAGAACTAATCGCTGTGGGTACAGAGATTTTGACAGGACAGATTGTCAACACCAACGCCCAATTTCTATCGGA
GAAATTTGCGGAGCTAGGGATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTGGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCACGATTTTTGGGGAGGGAGTTGGTATTTGATTCCCTAGCAATGGAGCGGCTGAACCGCTTTTTTGCCAGCCGGCC
AGGCCGAGTTCGGACTGCCAATAATGAGCGGCAAGCGCAGATTATTGCGGGAAGTCAGGCTCTTCAAAATCCGACTGGTT
TAGCAGTAGGTGGGTTGATAGAGCAGGATGGGGTGACCTATGTTGTGTTGCCTGGGCCTCCAGGAGAACTCAAGTCCATG
TTTGCACAAAGCCTACTGCCGCTTATTGGTCAATCCAACCAGCAGCTCTATTCCCGAGTCTTGCGTTTTTTTGGGATTGG
TGAGAGCCAGTTAGTGACGATTTTGGCGGACATGATTGAAAACCAAACAGATCCAACACTAGCCCCTTATGCAAAGACAG
GAGAAGTGACCCTTCGCCTGTCAACAAAATCAACCAGCTCTAGACAGGCCACAGCCAAGCTGGATCAGCTGGAAGCGGAG
ATTCTCAGCCATGCTAATCTAAGTGACTTGCTGTATGGCTATGGTGAGGATAATAGTCTGGCCCAAGTTGTTGCCCAATC
CTTGGGGGAACAACAACAGTCTATTGCGGTGGTTGAAAACTTGACAGCTGGGTTGCTGCAAGCCGACTTGACACTCGCTT
TACAGGATCGTCAACTTTACAAAGGCGGTCAAATTCTGACCAATAGCGAGGCCAATCTAGAGCTTGCCGGAAAAGAAGCA
GAGCGCATTCGTCAGTTGCACCAAACAGATAAGGGGTTAGCAGTCTTGGGAACCTTCAACCCACGCTCTCAAGCAGACAA
TGTAATGGCTACCTTTTATCTAGCAACAGCCAGTTTGGATGGCATCATAACAGAGGAAGTTGCACTTGGCGGTTACTCAT
GGCCAGCCATCCGTCAAATCGCCTGTATGAACGCTCTGGACCATGTGCGTAAGACTTTATGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

70.738

100

0.707
  cinA Streptococcus mutans UA159

57.908

100

0.606
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.385

92.621

0.374