Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   J7U22_RS08920 Genome accession   NZ_CP072428
Coordinates   1701942..1702883 (-) Length   313 a.a.
NCBI ID   WP_071417491.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24749     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1696942..1707883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS08880 (J7U22_08860) - 1697019..1698212 (-) 1194 WP_014608740.1 acetate kinase -
  J7U22_RS08885 (J7U22_08865) comYH 1698268..1699224 (-) 957 WP_372434691.1 class I SAM-dependent methyltransferase Machinery gene
  J7U22_RS08890 (J7U22_08870) comGG 1699269..1699586 (-) 318 WP_011681685.1 competence type IV pilus minor pilin ComGG -
  J7U22_RS08895 (J7U22_08875) comYF 1699564..1700001 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  J7U22_RS08900 (J7U22_08880) comGE 1699985..1700278 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  J7U22_RS08905 (J7U22_08885) comYD 1700250..1700678 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  J7U22_RS08910 (J7U22_08890) comYC 1700638..1700964 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  J7U22_RS08915 (J7U22_08895) comGB 1700961..1702060 (-) 1100 Protein_1699 competence type IV pilus assembly protein ComGB -
  J7U22_RS08920 (J7U22_08900) comGA/cglA/cilD 1701942..1702883 (-) 942 WP_071417491.1 competence type IV pilus ATPase ComGA Machinery gene
  J7U22_RS08925 (J7U22_08905) - 1702964..1703326 (-) 363 WP_014622006.1 DUF1033 family protein -
  J7U22_RS08930 (J7U22_08910) rpoC 1703484..1707122 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35411.58 Da        Isoelectric Point: 6.4142

>NTDB_id=552607 J7U22_RS08920 WP_071417491.1 1701942..1702883(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24749]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIHPIKDALDYRGLYLFAGPVGSGKTTLMHELVQEHFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLIGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=552607 J7U22_RS08920 WP_071417491.1 1701942..1702883(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain S24749]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCATCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCATTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACAGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAATAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTGCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

99.361

0.649
  comYA Streptococcus mutans UA159

64.217

100

0.642
  comYA Streptococcus mutans UA140

64.217

100

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.987

99.361

0.636
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.987

99.361

0.636
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.218

99.681

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

51.125

99.361

0.508
  comGA Latilactobacillus sakei subsp. sakei 23K

38.667

95.847

0.371