Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   SDSE_RS11290 Genome accession   NC_019042
Coordinates   112013..112954 (+) Length   313 a.a.
NCBI ID   WP_003055265.1    Uniprot ID   A0AB33R474
Organism   Streptococcus dysgalactiae subsp. equisimilis AC-2713     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 107013..117954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDSE_RS11280 (S_dysgal_equisimilis_AC2713_168) rpoC 107724..111365 (+) 3642 WP_015057200.1 DNA-directed RNA polymerase subunit beta' -
  SDSE_RS11285 (S_dysgal_equisimilis_AC2713_169) - 111567..111932 (+) 366 WP_003055257.1 DUF1033 family protein -
  SDSE_RS11290 (S_dysgal_equisimilis_AC2713_170) comGA/cglA 112013..112954 (+) 942 WP_003055265.1 competence type IV pilus ATPase ComGA Machinery gene
  SDSE_RS11295 (S_dysgal_equisimilis_AC2713_171) comYB 112890..113921 (+) 1032 WP_015057201.1 competence type IV pilus assembly protein ComGB Machinery gene
  SDSE_RS11300 (S_dysgal_equisimilis_AC2713_172) comYC 113923..114249 (+) 327 WP_003055259.1 competence type IV pilus major pilin ComGC Machinery gene
  SDSE_RS11305 (S_dysgal_equisimilis_AC2713_173) comGD 114224..114652 (+) 429 WP_041781473.1 competence type IV pilus minor pilin ComGD -
  SDSE_RS11310 (S_dysgal_equisimilis_AC2713_174) comGE 114660..114905 (+) 246 WP_003058569.1 competence type IV pilus minor pilin ComGE -
  SDSE_RS11315 (S_dysgal_equisimilis_AC2713_175) comGF 114886..115326 (+) 441 WP_003058520.1 competence type IV pilus minor pilin ComGF -
  SDSE_RS11320 (S_dysgal_equisimilis_AC2713_176) comGG 115349..115678 (+) 330 WP_003058539.1 competence type IV pilus minor pilin ComGG -
  SDSE_RS11325 (S_dysgal_equisimilis_AC2713_177) comYH 115741..116694 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  SDSE_RS11330 (S_dysgal_equisimilis_AC2713_178) - 116753..117949 (+) 1197 WP_015057203.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35224.31 Da        Isoelectric Point: 7.0642

>NTDB_id=54278 SDSE_RS11290 WP_003055265.1 112013..112954(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
MVQALARSILKEAEQIQAQDIYILPKEDQYELLIRVGDERRLVDVYRGDRMAHLISHFKFVAGMTVGEKRRCQVGSCDYD
IDGDTLLSLRLSSVGNYRGQESLVIRLLHHQQRSLHYWFDGLKTVARQIGGRGLYLFAGPVGSGKTTLMHQLIADYYQGA
QVISIEDPVEIKNHQALQLQVNDSIGMTYDNLIKLSLRHRPDILIIGEIRDSQTARAVIRASLTGVLVFSTVHAKSISGV
YARLLELGVTRAELDNCLALVAYQRLLNGGALIDSTQTEFEHYSPNQWNQKIDDLLAAGHLSPEQARFEKIIQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=54278 SDSE_RS11290 WP_003055265.1 112013..112954(+) (comGA/cglA) [Streptococcus dysgalactiae subsp. equisimilis AC-2713]
ATGGTACAAGCATTAGCAAGATCTATTTTGAAAGAAGCTGAGCAGATTCAAGCTCAAGATATCTATATTTTGCCAAAGGA
AGATCAGTATGAGCTATTGATAAGGGTAGGAGATGAAAGGAGATTGGTGGATGTTTATCGGGGCGATCGGATGGCTCATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGACCGTTGGTGAGAAACGACGCTGTCAAGTCGGTTCTTGTGATTATGAT
ATCGATGGAGACACACTTTTGTCTCTACGCCTGTCTAGTGTTGGAAATTACCGTGGACAAGAGAGCCTAGTGATTCGGTT
ATTACATCATCAACAAAGAAGTTTACATTACTGGTTTGACGGACTGAAAACAGTTGCACGTCAGATTGGAGGCCGAGGAC
TCTATCTTTTTGCAGGTCCAGTCGGATCAGGCAAAACGACTTTGATGCACCAATTGATTGCTGATTATTATCAAGGAGCA
CAGGTCATTAGCATAGAAGATCCGGTGGAAATTAAAAATCATCAAGCGCTCCAATTACAAGTTAATGATAGTATTGGCAT
GACTTACGACAACTTGATCAAACTATCTTTACGGCATCGCCCTGATATTTTAATCATTGGTGAAATTCGAGACAGCCAGA
CAGCTAGAGCGGTTATTAGAGCAAGTTTAACAGGTGTCTTAGTATTTTCAACAGTTCATGCCAAAAGCATTTCTGGTGTT
TATGCCAGATTACTAGAACTAGGAGTGACAAGAGCAGAATTAGACAATTGTTTGGCTTTGGTTGCTTACCAACGATTGCT
TAATGGAGGAGCATTGATTGACTCAACTCAAACAGAATTTGAACACTACTCACCAAACCAATGGAATCAGAAAATTGATG
ACCTTCTTGCAGCGGGACATCTCAGTCCGGAGCAAGCAAGGTTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.701

99.361

0.623
  comYA Streptococcus mutans UA140

61.736

99.361

0.613
  comYA Streptococcus mutans UA159

61.736

99.361

0.613
  comYA Streptococcus gordonii str. Challis substr. CH1

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

60.45

99.361

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.129

99.361

0.597
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.129

99.361

0.597
  comGA Lactococcus lactis subsp. cremoris KW2

52.09

99.361

0.518
  comGA Latilactobacillus sakei subsp. sakei 23K

38.908

93.61

0.364

Multiple sequence alignment