Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   I6J12_RS00030 Genome accession   NZ_CP068060
Coordinates   3315..3584 (+) Length   89 a.a.
NCBI ID   WP_003035361.1    Uniprot ID   I0SGR5
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 57..6003 3315..3584 within 0


Gene organization within MGE regions


Location: 57..6003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS00010 (I6J12_00010) - 845..1387 (+) 543 WP_003038192.1 DUF1366 domain-containing protein -
  I6J12_RS00015 (I6J12_00015) - 1405..1806 (+) 402 WP_003038210.1 hypothetical protein -
  I6J12_RS00020 (I6J12_00020) - 1808..2140 (+) 333 WP_003038184.1 phage holin -
  I6J12_RS00025 (I6J12_00025) - 2143..2892 (+) 750 WP_003038204.1 PlySs2 family phage lysin -
  I6J12_RS00030 (I6J12_00030) comYC 3315..3584 (+) 270 WP_003035361.1 competence type IV pilus major pilin ComGC Machinery gene
  I6J12_RS00035 (I6J12_00035) comYD 3544..3972 (+) 429 WP_020999411.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6J12_RS00040 (I6J12_00040) comGE/cglE 3944..4237 (+) 294 WP_003035318.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6J12_RS00045 (I6J12_00045) comGF/cglF 4221..4658 (+) 438 WP_003035329.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6J12_RS00050 (I6J12_00050) comGG 4639..4965 (+) 327 WP_020999447.1 competence type IV pilus minor pilin ComGG -
  I6J12_RS00055 (I6J12_00055) comYH 5050..6003 (+) 954 WP_003035359.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 89 a.a.        Molecular weight: 9806.44 Da        Isoelectric Point: 8.4759

>NTDB_id=526764 I6J12_RS00030 WP_003035361.1 3315..3584(+) (comYC) [Streptococcus anginosus strain FDAARGOS_1155]
MLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVSEGTITDKQAVSYKAYYAKH
TKEARTVAD

Nucleotide


Download         Length: 270 bp        

>NTDB_id=526764 I6J12_RS00030 WP_003035361.1 3315..3584(+) (comYC) [Streptococcus anginosus strain FDAARGOS_1155]
ATGTTAGTGGTGCTTCTAATCATCAGTGTTTTGATGCTTTTGTTTGTTCCGAATTTGACCAAACAAAAAGAAGCTGTAAC
GGAAAAAGGAAATGCAGCTGTTGTGAAGGTTGTCGAAAGTCAGGCAGAGCTTTTTGAAGTGAATCATACTAATGAAAAAG
CGACGCTTTCAAAATTAGTCAGTGAAGGAACTATTACAGACAAGCAAGCAGTATCATACAAGGCTTATTATGCAAAACAT
ACAAAAGAAGCTCGCACAGTTGCAGATTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SGR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

73.034

100

0.73
  comGC/cglC Streptococcus pneumoniae Rx1

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae D39

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae R6

65.169

100

0.652
  comGC/cglC Streptococcus pneumoniae TIGR4

65.169

100

0.652
  comGC/cglC Streptococcus mitis NCTC 12261

64

84.27

0.539
  comYC Streptococcus mutans UA140

64.384

82.022

0.528
  comYC Streptococcus mutans UA159

64.384

82.022

0.528
  comGC/cglC Streptococcus mitis SK321

62.667

84.27

0.528
  comYC Streptococcus suis isolate S10

63.014

82.022

0.517
  comGC Lactococcus lactis subsp. cremoris KW2

53.947

85.393

0.461