Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JH254_RS00990 Genome accession   NZ_CP066813
Coordinates   195876..197117 (+) Length   413 a.a.
NCBI ID   WP_200164280.1    Uniprot ID   -
Organism   Aeromonas caviae strain Aero52     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 190876..202117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JH254_RS00965 (JH254_00965) ampD 191244..191813 (-) 570 WP_180907147.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  JH254_RS00970 (JH254_00970) - 191926..192396 (+) 471 WP_042077632.1 TIGR02281 family clan AA aspartic protease -
  JH254_RS00975 (JH254_00975) nadC 192400..193287 (+) 888 WP_200164277.1 carboxylating nicotinate-nucleotide diphosphorylase -
  JH254_RS00980 (JH254_00980) - 193597..194037 (+) 441 WP_200164278.1 pilin -
  JH254_RS00985 (JH254_00985) pilB 194041..195747 (+) 1707 WP_200164279.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  JH254_RS00990 (JH254_00990) pilC 195876..197117 (+) 1242 WP_200164280.1 type II secretion system F family protein Machinery gene
  JH254_RS00995 (JH254_00995) pilD 197185..198060 (+) 876 WP_200164281.1 prepilin peptidase Machinery gene
  JH254_RS01000 (JH254_01000) coaE 198079..198693 (+) 615 WP_109111851.1 dephospho-CoA kinase -
  JH254_RS01005 (JH254_01005) zapD 198731..199453 (+) 723 WP_010675825.1 cell division protein ZapD -
  JH254_RS01010 (JH254_01010) yacG 199464..199658 (+) 195 WP_039040499.1 DNA gyrase inhibitor YacG -
  JH254_RS01015 (JH254_01015) mutT 199714..200118 (-) 405 WP_171864957.1 8-oxo-dGTP diphosphatase MutT -
  JH254_RS01020 (JH254_01020) - 200127..201311 (-) 1185 WP_200164282.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45554.53 Da        Isoelectric Point: 9.7229

>NTDB_id=522744 JH254_RS00990 WP_200164280.1 195876..197117(+) (pilC) [Aeromonas caviae strain Aero52]
MATLAQKQNAPKKIFSFRWHGFNRKGQKVSGELQADSINTVKLELYKQGVSVTRVSKQGQGLFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSEALRRHPRYFDDLYCDLVEAGEQSGALETIYDRI
AIYREKNEALKSKIKKAMFYPSMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTRFVITISRFMQEWWYAIFGGAA
LAVFLYVRAWRKSQKVRDNTDKFILTIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAIMAIR
NEVVAGMQINVAMRTVDLFPDMVTQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=522744 JH254_RS00990 WP_200164280.1 195876..197117(+) (pilC) [Aeromonas caviae strain Aero52]
ATGGCCACATTAGCTCAAAAACAGAACGCACCAAAAAAGATCTTCTCCTTCCGCTGGCACGGGTTCAATCGCAAGGGGCA
GAAGGTGTCCGGCGAGTTGCAGGCCGACAGCATCAATACCGTCAAGCTGGAACTGTACAAGCAGGGCGTCAGTGTCACCA
GGGTCAGCAAGCAGGGACAGGGGTTGTTCTCCAAGGGCGGCGCCCGGATCAAGCCGATGGACATCGCCGTCATCTCGCGC
CAGATCACCACCATGCTCTCCGCCGGCGTGCCCCTGGTACAGAGTCTGCAGATCATCGCACGCGGCCATGAAAAGGCGGC
GGTGCGCGAACTGATCGGCCAGATCGCCGCCGACGTGGAGACCGGCACCCCGCTGTCGGAGGCGCTGCGCCGCCATCCCC
GTTACTTTGATGATCTCTACTGCGATCTGGTCGAGGCAGGCGAGCAATCCGGTGCTCTGGAGACCATCTACGACCGGATT
GCCATCTACCGCGAGAAGAACGAAGCCCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCGTCCATGGTCATTCTGGT
GGCCATCGTCGTCACCTCCATCCTGCTGCTCTTCGTCATTCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCGCCTTTACCCGGTTCGTCATCACCATCTCCCGCTTTATGCAGGAGTGGTGGTACGCCATCTTTGGCGGCGCGGCT
CTCGCCGTCTTCCTCTATGTGCGGGCCTGGCGAAAATCCCAGAAGGTCAGGGACAACACGGACAAGTTCATCCTCACCAT
TCCCGTGGTGGGCAACATACTGCACAAGGCGGCCATGGCCCGCTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TCCCCCTGGTGGATGCGCTGGTCTCGGCGGCCGGGGCGTCGGGCAACTATGTCTATCGCACCGCCATCATGGCCATCCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTCTTCCCCGACATGGTGACCCAGATGGT
GATGATCGGCGAGGAGTCCGGCGCCATCGATGACATGCTCTCCAAGGTCGCAGCCATCTTCGAACAGGAGGTGGACGACA
TGGTCGACGGCCTCACCAGCCTGCTGGAACCCATCATCATGGTGGTACTCGGCGTGCTGGTCGGCGGCATGGTCGTGGCC
ATGTACCTCCCCATCTTCAAGCTCGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

55.556

95.884

0.533
  pilC Legionella pneumophila strain ERS1305867

51.852

98.063

0.508
  pilC Acinetobacter baumannii D1279779

51.621

97.094

0.501
  pilC Acinetobacter baylyi ADP1

51.128

96.61

0.494
  pilC Vibrio cholerae strain A1552

46.929

98.547

0.462
  pilC Vibrio campbellii strain DS40M4

44.608

98.789

0.441
  pilG Neisseria meningitidis 44/76-A

40.494

98.063

0.397
  pilG Neisseria gonorrhoeae MS11

40.494

98.063

0.397
  pilC Thermus thermophilus HB27

38.25

96.852

0.37