Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   JC622_RS20910 Genome accession   NZ_CP066125
Coordinates   4468393..4469634 (+) Length   413 a.a.
NCBI ID   WP_005336136.1    Uniprot ID   A0A0T6QCE0
Organism   Aeromonas veronii strain 32286     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4463393..4474634
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JC622_RS20885 ampD 4463646..4464218 (-) 573 WP_227095384.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  JC622_RS20890 - 4464330..4464800 (+) 471 WP_227095385.1 TIGR02281 family clan AA aspartic protease -
  JC622_RS20895 nadC 4464804..4465679 (+) 876 WP_227095386.1 carboxylating nicotinate-nucleotide diphosphorylase -
  JC622_RS20900 - 4466012..4466443 (+) 432 WP_227096674.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  JC622_RS20905 pilB 4466450..4468156 (+) 1707 WP_227095387.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  JC622_RS20910 pilC 4468393..4469634 (+) 1242 WP_005336136.1 type II secretion system F family protein Machinery gene
  JC622_RS20915 pilD 4469695..4470567 (+) 873 WP_227095388.1 A24 family peptidase Machinery gene
  JC622_RS20920 coaE 4470581..4471195 (+) 615 WP_227095389.1 dephospho-CoA kinase -
  JC622_RS20925 zapD 4471233..4471955 (+) 723 WP_005355104.1 cell division protein ZapD -
  JC622_RS20930 yacG 4471965..4472159 (+) 195 WP_201908670.1 DNA gyrase inhibitor YacG -
  JC622_RS20935 mutT 4472237..4472641 (-) 405 WP_227095390.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45427.55 Da        Isoelectric Point: 9.7221

>NTDB_id=517623 JC622_RS20910 WP_005336136.1 4468393..4469634(+) (pilC) [Aeromonas veronii strain 32286]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGDVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=517623 JC622_RS20910 WP_005336136.1 4468393..4469634(+) (pilC) [Aeromonas veronii strain 32286]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTACAGGCCGACAGCATCAACACCGTCAAGACCGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTGGCCAAAAAATCCCAAGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCCCGT
CAGATCACCACCATGCTCTCCGCCGGTGTACCGCTGGTACAGAGCCTGCAGATCATCGCCCGCAGTCACGAAAAAGCCTC
GATGCGCGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACCGGTACCCCCATGTCGGAGGCGCTGCGTCGCCATCCTC
TCTATTTCGATGATCTCTACTGCGATCTGGTGGAAGCCGGTGAGCAATCCGGTGCGCTGGAAACCATCTACGACCGTATC
GCAACCTATCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCCATCGTGGTCACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTCGGCGCCGAGC
TGCCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACGGCC
CTTGGCATCTTCCTTTACGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTAGTCGGGATGATCCTGCACAAGGCGGCGATGGCCCGCTTTGCCCGCACCCTGTCTACCACCTTCTCCGCCGGTA
TTCCGCTGGTAGATGCGCTGATTTCGGCAGCAGGTGCCTCCGGCAACTATGTCTATCGCACCGCGGTCATGGCGATCCGT
AATGAGGTGGTGGCAGGCATGCAGATCAACGTGGCGATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAGGAGTCCGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATCGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGACGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T6QCE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368