Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6H78_RS06615 Genome accession   NZ_CP066059
Coordinates   1355760..1357016 (+) Length   418 a.a.
NCBI ID   WP_198459180.1    Uniprot ID   A0A7T4IRR7
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1350760..1362016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS06590 (I6H78_06590) ndk 1352427..1352846 (+) 420 WP_198459177.1 nucleoside-diphosphate kinase -
  I6H78_RS06595 (I6H78_06595) comM 1352981..1353604 (+) 624 WP_096408900.1 hypothetical protein Regulator
  I6H78_RS06600 (I6H78_06600) tsaE 1353688..1354131 (+) 444 WP_198459178.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  I6H78_RS06605 (I6H78_06605) - 1354121..1354642 (+) 522 WP_198459179.1 GNAT family N-acetyltransferase -
  I6H78_RS06610 (I6H78_06610) brpA 1354647..1355687 (+) 1041 WP_000592174.1 biofilm formation/cell division transcriptional regulator BrpA -
  I6H78_RS06615 (I6H78_06615) cinA 1355760..1357016 (+) 1257 WP_198459180.1 competence/damage-inducible protein A Machinery gene
  I6H78_RS06620 (I6H78_06620) recA 1357071..1358222 (+) 1152 WP_001085520.1 recombinase RecA Machinery gene
  I6H78_RS06625 (I6H78_06625) - 1358350..1358544 (+) 195 WP_198459181.1 PspC domain-containing protein -
  I6H78_RS06630 (I6H78_06630) - 1358676..1359230 (-) 555 WP_198459182.1 GNAT family N-acetyltransferase -
  I6H78_RS06635 (I6H78_06635) - 1359340..1360710 (+) 1371 WP_198459183.1 MATE family efflux transporter -
  I6H78_RS06640 (I6H78_06640) - 1360807..1361523 (+) 717 WP_049524687.1 YebC/PmpR family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45165.51 Da        Isoelectric Point: 4.8408

>NTDB_id=516981 I6H78_RS06615 WP_198459180.1 1355760..1357016(+) (cinA) [Streptococcus oralis strain FDAARGOS_1021]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARIKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHTKGTEVIKANIAGRSRADVR
QIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=516981 I6H78_RS06615 WP_198459180.1 1355760..1357016(+) (cinA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAGCAGAAATTATTGCTGTCGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTACTTCCAAACTGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AAATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACCGAGGATGATTTGACCAAACAAACT
CTGGCAAAATTTTTAGGAAAAGCTCTAGTGTTTGACCCTCAAGCACAAGAGAAATTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCAACTCCACTGCCAAATGAAACAGGTT
TAGCAGTCGGAGGGGTGTCGGAAGTGGATGGCGTGACCTACGTGGTCCTTCCAGGACCACCAAGTGAGTTGAAACCCATG
GTCTTAAATCAACTCTTACCCAAGTTAATGACTGGTACCAAGTTATACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTAGCGGATTTGATTGACCATCAAACCGATCCGACTTTGGCGCCGTATGCCAAGACGGGAG
AAGTTACCTTGCGCTTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGCACTGGACATCCTAGAAAATCAAATC
TTGGATCGTCAAACTTTCGAGGGGATTTCTCTACGAGACATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTCGGGCGTTTCAGCTATCTTTAATGGTGGTTTTGTCACTTACAGCCTAGAAGAAAAGTCTAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGAT
CAAGACTCAGTCTGACTACGGAGTTAGTTTGACGGGTGTGGCAGGGCCAGATAGCCTAGAGGGGCATCCAGCTGGTACAG
TTTTTATTGGACTGGCACATACAAAAGGGACAGAGGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTTCGA
CAGATTGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4IRR7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus pneumoniae TIGR4

89.952

100

0.9
  cinA Streptococcus pneumoniae Rx1

89.952

100

0.9
  cinA Streptococcus pneumoniae R6

89.952

100

0.9
  cinA Streptococcus pneumoniae D39

89.713

100

0.897
  cinA Streptococcus mitis NCTC 12261

89.234

100

0.892
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455