Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   I6H78_RS06595 Genome accession   NZ_CP066059
Coordinates   1352981..1353604 (+) Length   207 a.a.
NCBI ID   WP_096408900.1    Uniprot ID   A0A7T4LZX0
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1347981..1358604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS06585 (I6H78_06585) rpoC 1348651..1352316 (+) 3666 WP_198459176.1 DNA-directed RNA polymerase subunit beta' -
  I6H78_RS06590 (I6H78_06590) ndk 1352427..1352846 (+) 420 WP_198459177.1 nucleoside-diphosphate kinase -
  I6H78_RS06595 (I6H78_06595) comM 1352981..1353604 (+) 624 WP_096408900.1 hypothetical protein Regulator
  I6H78_RS06600 (I6H78_06600) tsaE 1353688..1354131 (+) 444 WP_198459178.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  I6H78_RS06605 (I6H78_06605) - 1354121..1354642 (+) 522 WP_198459179.1 GNAT family N-acetyltransferase -
  I6H78_RS06610 (I6H78_06610) brpA 1354647..1355687 (+) 1041 WP_000592174.1 biofilm formation/cell division transcriptional regulator BrpA -
  I6H78_RS06615 (I6H78_06615) cinA 1355760..1357016 (+) 1257 WP_198459180.1 competence/damage-inducible protein A Machinery gene
  I6H78_RS06620 (I6H78_06620) recA 1357071..1358222 (+) 1152 WP_001085520.1 recombinase RecA Machinery gene
  I6H78_RS06625 (I6H78_06625) - 1358350..1358544 (+) 195 WP_198459181.1 PspC domain-containing protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23718.67 Da        Isoelectric Point: 9.2521

>NTDB_id=516980 I6H78_RS06595 WP_096408900.1 1352981..1353604(+) (comM) [Streptococcus oralis strain FDAARGOS_1021]
MVKSIRLLLLIAVIQISFSSCLLWKESFLSLKQTNAYFLILIVGFSVLCAGINYFHTADQSRHSILHVQKKVSLVYCLLL
VVNLLATCLVLSESIQTTSKLQQELVDLFLPSFFFLLGVDLLIFLPFDKIFRDIENHLNKKKTVVISVLATMVFLRNPLV
ISSILLYISVGFLCARFLFPKCIQREISFYGHLIRDILFVFSIVVFF

Nucleotide


Download         Length: 624 bp        

>NTDB_id=516980 I6H78_RS06595 WP_096408900.1 1352981..1353604(+) (comM) [Streptococcus oralis strain FDAARGOS_1021]
ATGGTAAAATCAATTCGCCTATTGTTATTGATTGCAGTCATCCAGATTAGTTTTAGTAGTTGTCTATTATGGAAAGAATC
CTTTTTATCTTTAAAACAGACCAATGCTTACTTTTTGATTTTGATAGTAGGATTTTCTGTTCTTTGTGCTGGGATAAATT
ATTTCCATACAGCAGACCAGTCTAGACATAGTATTTTACATGTTCAAAAGAAAGTGAGTCTTGTTTATTGCCTCCTTTTA
GTAGTCAATCTTCTTGCAACCTGTCTGGTTCTCTCAGAAAGCATCCAAACCACTAGCAAATTGCAGCAGGAACTGGTTGA
CCTCTTTTTACCCTCCTTCTTTTTCTTGCTAGGAGTAGATCTATTGATTTTCTTACCTTTTGATAAAATTTTTCGCGATA
TAGAAAATCACCTAAATAAAAAGAAAACAGTCGTCATTTCCGTTCTAGCTACGATGGTTTTCTTGAGGAATCCCTTAGTG
ATTTCCTCGATTCTCCTTTACATCAGTGTCGGTTTTCTATGCGCACGTTTCCTTTTTCCAAAATGTATTCAAAGGGAAAT
CTCCTTTTACGGACACCTGATTCGGGATATTCTGTTTGTTTTTTCAATAGTTGTATTCTTTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4LZX0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

51.456

99.517

0.512
  comM Streptococcus pneumoniae R6

51.456

99.517

0.512
  comM Streptococcus pneumoniae TIGR4

51.456

99.517

0.512
  comM Streptococcus mitis NCTC 12261

40.609

95.169

0.386
  comM Streptococcus mitis SK321

40.609

95.169

0.386