Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   I6I32_RS05445 Genome accession   NZ_CP066041
Coordinates   1107956..1108081 (+) Length   41 a.a.
NCBI ID   WP_000799678.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 1102956..1113081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS05420 (I6I32_05420) dnaA 1103420..1104781 (-) 1362 WP_000660623.1 chromosomal replication initiator protein DnaA -
  I6I32_RS05425 (I6I32_05425) spo0J 1104998..1105756 (-) 759 WP_198464230.1 ParB/RepB/Spo0J family partition protein Regulator
  I6I32_RS05430 (I6I32_05430) htrA 1105814..1107010 (-) 1197 WP_125414985.1 S1C family serine protease Regulator
  I6I32_RS05435 (I6I32_05435) rlmH 1107196..1107675 (+) 480 WP_198464231.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6I32_RS05445 (I6I32_05445) comC/comC2 1107956..1108081 (+) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  I6I32_RS05450 (I6I32_05450) comD 1108102..1109421 (+) 1320 WP_198464232.1 competence system sensor histidine kinase ComD Regulator
  I6I32_RS05455 (I6I32_05455) comE 1109418..1110170 (+) 753 WP_000866079.1 competence system response regulator transcription factor ComE Regulator
  I6I32_RS05470 (I6I32_05470) - 1110408..1110950 (-) 543 WP_000665080.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4960.73 Da        Isoelectric Point: 10.3052

>NTDB_id=516660 I6I32_RS05445 WP_000799678.1 1107956..1108081(+) (comC/comC2) [Streptococcus oralis strain FDAARGOS_1075]
MKNTVKLEQFKEVTEAELQEIRGGDWRISETIRNLIFPRRK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=516660 I6I32_RS05445 WP_000799678.1 1107956..1108081(+) (comC/comC2) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAAAATACAGTAAAGTTGGAACAATTTAAAGAAGTAACAGAGGCAGAATTGCAGGAGATTCGAGGTGGAGATTGGAG
AATTTCAGAAACAATTCGTAATCTTATTTTTCCAAGAAGAAAGTAA

Domains

Predicted by InterproScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

56.098

100

0.561
  comC/comC2 Streptococcus pneumoniae TIGR4

56.098

100

0.561
  comC Streptococcus mitis SK321

56.098

100

0.561
  comC/comC1 Streptococcus pneumoniae R6

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae G54

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae D39

53.659

100

0.537
  comC/comC1 Streptococcus pneumoniae Rx1

53.659

100

0.537
  comC Streptococcus mitis NCTC 12261

47.5

97.561

0.463
  comC/comC2 Streptococcus gordonii strain NCTC7865

43.243

90.244

0.39
  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

39.474

92.683

0.366