Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   I6I32_RS05450 Genome accession   NZ_CP066041
Coordinates   1108102..1109421 (+) Length   439 a.a.
NCBI ID   WP_198464232.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1103102..1114421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS05420 (I6I32_05420) dnaA 1103420..1104781 (-) 1362 WP_000660623.1 chromosomal replication initiator protein DnaA -
  I6I32_RS05425 (I6I32_05425) spo0J 1104998..1105756 (-) 759 WP_198464230.1 ParB/RepB/Spo0J family partition protein Regulator
  I6I32_RS05430 (I6I32_05430) htrA 1105814..1107010 (-) 1197 WP_125414985.1 S1C family serine protease Regulator
  I6I32_RS05435 (I6I32_05435) rlmH 1107196..1107675 (+) 480 WP_198464231.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6I32_RS05445 (I6I32_05445) comC/comC2 1107956..1108081 (+) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  I6I32_RS05450 (I6I32_05450) comD 1108102..1109421 (+) 1320 WP_198464232.1 competence system sensor histidine kinase ComD Regulator
  I6I32_RS05455 (I6I32_05455) comE 1109418..1110170 (+) 753 WP_000866079.1 competence system response regulator transcription factor ComE Regulator
  I6I32_RS05470 (I6I32_05470) - 1110408..1110950 (-) 543 WP_000665080.1 TetR/AcrR family transcriptional regulator -
  I6I32_RS05475 (I6I32_05475) - 1111079..1113733 (+) 2655 WP_198464233.1 YhgE/Pip domain-containing protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51214.22 Da        Isoelectric Point: 7.2201

>NTDB_id=516661 I6I32_RS05450 WP_198464232.1 1108102..1109421(+) (comD) [Streptococcus oralis strain FDAARGOS_1075]
MDLFGLGIAIFYFLIISKSYEWICKINRKEQIVFFCYTCISVFILEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKAIFISLLLSLLYHSTHTFISVTLSSITGDEVVLHYKSTFLLVVLLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHILLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAINSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDIITRLSIDLLDLVRIMSILLNNAVEGAADSYLKQMDVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=516661 I6I32_RS05450 WP_198464232.1 1108102..1109421(+) (comD) [Streptococcus oralis strain FDAARGOS_1075]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTCTCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTATACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTACCTTTATTTAAGAAAATTAAAGAAGTCTGAAAAA
TACAAAGCTATTTTTATCAGTTTACTATTGTCTTTATTATATCACAGTACTCATACTTTTATATCTGTAACCTTATCTTC
TATAACAGGAGATGAAGTAGTATTACATTATAAAAGTACATTCCTTTTAGTGGTATTGTTGATGACTTATTTTTCTATTC
TAATAATAATTCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTATCCTTTTTTAAAAAAAGTAATA
GTTGCTTTTTTTGGTTTGCATATCTTATTATTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGACTATGCAGGGATGCTTGTTAGCATGCAAATGGCGATTAACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTATTTTGATTTAAATA
ATATAGAAGATTCTGCTTTACGAAGTTTAATTGCTCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAGGATATCATTACTAGACTGTCAATAGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAACAATGC
TGTTGAAGGTGCAGCAGATAGTTACTTGAAACAAATGGACGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATAACTATGACGCCTTCAGAGGACCTATTTGCCTTAGGTTTTTCTACCAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAAGAGATTTTAGATAAGTATGACAACATTATTTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTCGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

74.83

100

0.752
  comD/comD2 Streptococcus pneumoniae TIGR4

73.923

100

0.743
  comD Streptococcus mitis NCTC 12261

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae R6

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae Rx1

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae D39

73.469

100

0.738
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50

85.194

0.426
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.468

85.649

0.424