Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6H77_RS05315 Genome accession   NZ_CP066021
Coordinates   1085806..1087062 (+) Length   418 a.a.
NCBI ID   WP_000642669.1    Uniprot ID   A0A0F2D2E5
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1080806..1092062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS05290 (I6H77_05290) ndk 1082473..1082892 (+) 420 WP_000438309.1 nucleoside-diphosphate kinase -
  I6H77_RS05295 (I6H77_05295) comM 1083027..1083650 (+) 624 WP_000240908.1 hypothetical protein Regulator
  I6H77_RS05300 (I6H77_05300) tsaE 1083734..1084177 (+) 444 WP_000556960.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  I6H77_RS05305 (I6H77_05305) - 1084167..1084688 (+) 522 WP_000455521.1 GNAT family N-acetyltransferase -
  I6H77_RS05310 (I6H77_05310) brpA 1084693..1085733 (+) 1041 WP_000592174.1 biofilm formation/cell division transcriptional regulator BrpA -
  I6H77_RS05315 (I6H77_05315) cinA 1085806..1087062 (+) 1257 WP_000642669.1 competence/damage-inducible protein A Machinery gene
  I6H77_RS05320 (I6H77_05320) recA 1087117..1088265 (+) 1149 WP_001085515.1 recombinase RecA Machinery gene
  I6H77_RS05325 (I6H77_05325) - 1088435..1088629 (+) 195 WP_000415528.1 PspC domain-containing protein -
  I6H77_RS05330 (I6H77_05330) - 1088760..1089314 (-) 555 WP_000060285.1 GNAT family N-acetyltransferase -
  I6H77_RS05335 (I6H77_05335) - 1089424..1090794 (+) 1371 WP_002874864.1 MATE family efflux transporter -
  I6H77_RS05340 (I6H77_05340) - 1090891..1091607 (+) 717 WP_000532891.1 YebC/PmpR family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45247.63 Da        Isoelectric Point: 4.7813

>NTDB_id=516480 I6H77_RS05315 WP_000642669.1 1085806..1087062(+) (cinA) [Streptococcus oralis strain FDAARGOS_1020]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVLEVDGVTYVVLPGPPSELKPM
VLNQLLPMLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKTLLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=516480 I6H77_RS05315 WP_000642669.1 1085806..1087062(+) (cinA) [Streptococcus oralis strain FDAARGOS_1020]
ATGAAAGCAGAAATTATTGCTGTCGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTACTTCCAAACTGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACC
CTGGCAAAATTTTTAGGAAAAGATCTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGAGTATTGGAAGTGGATGGTGTAACCTACGTGGTCCTTCCAGGACCACCTAGTGAATTGAAACCTATG
GTATTAAATCAACTCTTGCCCATGCTGATGACAGGAACCAAACTGTACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTGGCGGATTTGATTGACCATCAAACCGATCCGACTTTGGCACCGTATGCCAAAACAGGAG
AAGTGACCTTGCGCTTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGCACTGGACATCTTAGAAAATCAAATC
TTGGATCGTCAAACTTTCGAGGGGATTTCTCTACGAGATATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTCGGGCGTTTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGTTTAGAAGAAAAGTCTAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGGCATCCAGCTGGCACAG
TTTTTATTGGACTGGCACATGCAAAAGGGACAGAAGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTACGT
CACATCGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGACTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2D2E5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus pneumoniae TIGR4

89.713

100

0.897
  cinA Streptococcus pneumoniae Rx1

89.713

100

0.897
  cinA Streptococcus pneumoniae R6

89.713

100

0.897
  cinA Streptococcus pneumoniae D39

89.474

100

0.895
  cinA Streptococcus mitis NCTC 12261

88.995

100

0.89
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452