Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   JAN99_RS00655 Genome accession   NZ_CP065927
Coordinates   102035..102973 (+) Length   312 a.a.
NCBI ID   WP_002993471.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm9ST603     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 97035..107973
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JAN99_RS00645 (JAN99_00640) rpoC 97784..101425 (+) 3642 WP_111692970.1 DNA-directed RNA polymerase subunit beta' -
  JAN99_RS00650 (JAN99_00645) - 101577..101942 (+) 366 WP_002986560.1 DUF1033 family protein -
  JAN99_RS00655 (JAN99_00650) comYA 102035..102973 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  JAN99_RS00660 (JAN99_00655) comYB 102909..103943 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  JAN99_RS00665 (JAN99_00660) comYC 103945..104271 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  JAN99_RS00670 (JAN99_00665) comGD 104246..104674 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  JAN99_RS00675 (JAN99_00670) comGE 104631..104915 (+) 285 WP_269460045.1 competence type IV pilus minor pilin ComGE -
  JAN99_RS00680 (JAN99_00675) comYF 104908..105342 (+) 435 WP_002987783.1 competence type IV pilus minor pilin ComGF Machinery gene
  JAN99_RS00685 (JAN99_00680) comGG 105326..105652 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  JAN99_RS00690 (JAN99_00685) comYH 105750..106703 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  JAN99_RS00695 (JAN99_00690) - 106762..107958 (+) 1197 WP_002987791.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35032.27 Da        Isoelectric Point: 8.5799

>NTDB_id=515342 JAN99_RS00655 WP_002993471.1 102035..102973(+) (comYA) [Streptococcus pyogenes strain emm9ST603]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=515342 JAN99_RS00655 WP_002993471.1 102035..102973(+) (comYA) [Streptococcus pyogenes strain emm9ST603]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

60.772

99.679

0.606
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.645

99.359

0.603
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.679

0.596
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.679

0.59
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369