Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I6G43_RS02000 Genome accession   NZ_CP065706
Coordinates   407324..408580 (+) Length   418 a.a.
NCBI ID   WP_000642699.1    Uniprot ID   A0A7T3DW57
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 402324..413580
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS01980 (I6G43_01980) comM 404531..405154 (+) 624 WP_009014110.1 hypothetical protein Regulator
  I6G43_RS01985 (I6G43_01985) tsaE 405258..405701 (+) 444 WP_000288226.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  I6G43_RS01990 (I6G43_01990) - 405691..406212 (+) 522 WP_000455526.1 GNAT family N-acetyltransferase -
  I6G43_RS01995 (I6G43_01995) brpA 406217..407251 (+) 1035 WP_009014109.1 biofilm formation/cell division transcriptional regulator BrpA -
  I6G43_RS02000 (I6G43_02000) cinA 407324..408580 (+) 1257 WP_000642699.1 competence/damage-inducible protein A Machinery gene
  I6G43_RS02005 (I6G43_02005) recA 408635..409783 (+) 1149 WP_038806436.1 recombinase RecA Machinery gene
  I6G43_RS02010 (I6G43_02010) - 409840..410394 (-) 555 WP_038806435.1 GNAT family N-acetyltransferase -
  I6G43_RS02015 (I6G43_02015) - 410504..411874 (+) 1371 WP_038806434.1 MATE family efflux transporter -
  I6G43_RS02020 (I6G43_02020) - 411971..412687 (+) 717 WP_038806433.1 YebC/PmpR family DNA-binding transcriptional regulator -
  I6G43_RS02025 (I6G43_02025) - 412735..413433 (-) 699 WP_038806432.1 DUF308 domain-containing protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45116.41 Da        Isoelectric Point: 4.8443

>NTDB_id=513201 I6G43_RS02000 WP_000642699.1 407324..408580(+) (cinA) [Streptococcus oralis strain FDAARGOS_886]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLMSLLEIASSRSSLVILTGGLGPTEDDLTKQT
LAKFLGKGLVFDPQAQEKLDVFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGTKLYSRVLRFFGIGESQLVTILADLIDNQTDPTLAPYAKTGEVTLRLSTKALSQEKADQALDTLENQI
LDRQTFEELSLRDICYGYGEETSLASVVVEELKKRKRSITAAESLTAGLFQATLANFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTAQKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=513201 I6G43_RS02000 WP_000642699.1 407324..408580(+) (cinA) [Streptococcus oralis strain FDAARGOS_886]
ATGAAAGCAGAAATCATTGCTGTAGGAACGGAAATTTTAACAGGGCAGATCGTCAATACCAACGCACAGTTTTTATCAGA
AAAGCTAGCAGAAATTGGAGTAGATGTCTACTTCCAAACAGCTGTCGGAGATAATGAAGCGCGTCTCATGTCCTTGCTAG
AGATTGCGAGTTCGCGTAGTAGTCTAGTCATTTTGACAGGGGGCTTAGGGCCAACTGAGGATGATTTGACCAAACAAACT
CTGGCAAAATTTTTGGGAAAAGGTTTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATGTCTTTTTTGCTCATAGACC
TGACTATGCTCGGACACCCAATAACGAGAGGCAAGCTCAAATTGTAGAAGGGGCAACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTATCGGAAGTGGATGGCGTGACTTACGTAGTCCTTCCAGGACCTCCTAGTGAGCTGAAACCCATG
GTCTTAAATCAGCTCTTACCTAAGTTAATGACTGGTACCAAGTTATACTCACGTGTGCTCCGTTTCTTTGGGATTGGTGA
AAGTCAGTTGGTGACCATTTTGGCGGATTTGATTGATAATCAAACCGATCCGACCTTGGCACCTTATGCCAAAACGGGAG
AGGTGACCTTGCGCTTGTCCACAAAAGCACTCAGTCAAGAAAAGGCTGATCAAGCATTGGACACCTTGGAAAATCAAATC
TTAGATCGCCAGACTTTCGAAGAACTTTCTCTGCGAGACATCTGTTATGGATATGGGGAGGAGACCAGCCTAGCAAGTGT
CGTTGTAGAAGAGCTTAAGAAGAGAAAGAGAAGCATTACTGCAGCAGAGAGCTTGACGGCAGGCCTCTTTCAGGCTACTT
TAGCGAACTTTTCAGGCGTTTCTGCTATCTTTAATGGTGGTTTTGTCACATATAGTCTAGAAGAAAAGTCCAAGATGCTG
GATATTTCCGAGCAAGAGCTGAAAGAACACGGGGTTGTCTCAGAGTTTACGGCTCAAAAGATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGACTACGGAGTCAGTTTGACGGGTGTGGCTGGGCCAGATAGCCTAGAGGGGCATCCAGCTGGGACAG
TCTTTATCGGATTGGCACATGCAAAAGGGACAGAAGTTATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTACGT
CACATCGCGGTCATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T3DW57

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus pneumoniae TIGR4

89.234

100

0.892
  cinA Streptococcus pneumoniae Rx1

89.234

100

0.892
  cinA Streptococcus pneumoniae R6

89.234

100

0.892
  cinA Streptococcus mitis NCTC 12261

88.995

100

0.89
  cinA Streptococcus pneumoniae D39

88.995

100

0.89
  cinA Streptococcus mutans UA159

70.096

100

0.701
  cinA Streptococcus suis isolate S10

54.087

99.522

0.538
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452