NTDB

Overview

Name	comGG/cglG	Type	Machinery gene
Locus tag	I6G43_RS01790	Genome accession	NZ_CP065706
Coordinates	366371..366796 (+)	Length	141 a.a.
NCBI ID	WP_000265654.1	Uniprot ID	A0A7T2ZNR3
Organism	Streptococcus oralis strain FDAARGOS_886
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 361371..371796

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS01750 (I6G43_01750)	tnpA	361832..362347 (-)	516	Protein_329	IS200/IS605 family transposase	-
I6G43_RS01755 (I6G43_01755)	-	362646..363011 (+)	366	WP_038805747.1	DUF1033 family protein	-
I6G43_RS01760 (I6G43_01760)	comGA/cglA/cilD	363077..364018 (+)	942	WP_038805745.1	competence type IV pilus ATPase ComGA	Machinery gene
I6G43_RS01765 (I6G43_01765)	comGB/cglB	363966..364982 (+)	1017	WP_068981970.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6G43_RS01770 (I6G43_01770)	comGC/cglC	364984..365307 (+)	324	WP_038805744.1	competence type IV pilus major pilin ComGC	Machinery gene
I6G43_RS01775 (I6G43_01775)	comGD/cglD	365270..365704 (+)	435	WP_038805743.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6G43_RS01780 (I6G43_01780)	comGE/cglE	365667..365969 (+)	303	WP_000413373.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6G43_RS01785 (I6G43_01785)	comGF/cglF	365932..366393 (+)	462	WP_000531552.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6G43_RS01790 (I6G43_01790)	comGG/cglG	366371..366796 (+)	426	WP_000265654.1	competence type IV pilus minor pilin ComGG	Machinery gene
I6G43_RS01795 (I6G43_01795)	-	366806..367396 (+)	591	WP_000679771.1	class I SAM-dependent methyltransferase	-
I6G43_RS01800 (I6G43_01800)	comYH	367455..368408 (+)	954	WP_001008566.1	class I SAM-dependent methyltransferase	Machinery gene
I6G43_RS01805 (I6G43_01805)	-	368458..369648 (+)	1191	WP_000167782.1	acetate kinase	-
I6G43_RS01810 (I6G43_01810)	rnpA	369808..370179 (+)	372	WP_000748125.1	ribonuclease P protein component	-
I6G43_RS01815 (I6G43_01815)	-	370154..370966 (+)	813	WP_000728102.1	YidC/Oxa1 family membrane protein insertase	-

Sequence

Protein

Download Length: 141 a.a. Molecular weight: 16100.53 Da Isoelectric Point: 10.6584

                                >NTDB_id=513196 I6G43_RS01790 WP_000265654.1 366371..366796(+) (comGG/cglG) [Streptococcus oralis strain FDAARGOS_886]

MWKKQKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHHKGFTLNKEKLVAFAMAKRSKDKAEQESGERVFNLGKVTYQNTK

TGFATSVRMNRSNYEFLFPSMKPKEKKTDPKEQLSTNSSQQTNQKETDHKADKKGNSTSLC

Nucleotide

Download Length: 426 bp

                                >NTDB_id=513196 I6G43_RS01790 WP_000265654.1 366371..366796(+) (comGG/cglG) [Streptococcus oralis strain FDAARGOS_886]

GTGTGGAAAAAGCAAAAAGTTAAGGCAGGTGTTCTTTTATATGCAGTCACCATGGCAGCCATTTTTAGCCTTTTGCTACA

GTTTTATTTGAATCGTCAAGTTGCCCATCACAAAGGCTTTACCCTAAACAAAGAAAAGTTGGTCGCTTTTGCCATGGCCA

AACGAAGCAAAGATAAGGCTGAGCAAGAAAGTGGGGAACGAGTCTTTAACCTAGGAAAAGTCACTTATCAAAATACCAAA

ACAGGTTTTGCAACAAGTGTTCGAATGAATAGGAGCAACTATGAATTTCTCTTTCCTTCGATGAAACCCAAGGAAAAGAA

AACGGACCCTAAGGAACAATTATCTACCAACTCAAGTCAACAAACCAATCAGAAAGAAACAGACCATAAGGCAGATAAGA

AAGGCAATTCAACTTCTTTGTGTTAA

Domains

No domain identified.

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A7T2ZNR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGG/cglG	Streptococcus mitis NCTC 12261	76.033	85.816	0.652
comGG/cglG	Streptococcus mitis SK321	71.074	85.816	0.61
comGG/cglG	Streptococcus pneumoniae Rx1	78.218	71.631	0.56
comGG/cglG	Streptococcus pneumoniae D39	78.218	71.631	0.56
comGG/cglG	Streptococcus pneumoniae R6	78.218	71.631	0.56
comGG/cglG	Streptococcus pneumoniae TIGR4	78.218	71.631	0.56

Detailed information NTG0513196