Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   I6G43_RS01800 Genome accession   NZ_CP065706
Coordinates   367455..368408 (+) Length   317 a.a.
NCBI ID   WP_001008566.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 362455..373408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS01755 (I6G43_01755) - 362646..363011 (+) 366 WP_038805747.1 DUF1033 family protein -
  I6G43_RS01760 (I6G43_01760) comGA/cglA/cilD 363077..364018 (+) 942 WP_038805745.1 competence type IV pilus ATPase ComGA Machinery gene
  I6G43_RS01765 (I6G43_01765) comGB/cglB 363966..364982 (+) 1017 WP_068981970.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6G43_RS01770 (I6G43_01770) comGC/cglC 364984..365307 (+) 324 WP_038805744.1 competence type IV pilus major pilin ComGC Machinery gene
  I6G43_RS01775 (I6G43_01775) comGD/cglD 365270..365704 (+) 435 WP_038805743.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6G43_RS01780 (I6G43_01780) comGE/cglE 365667..365969 (+) 303 WP_000413373.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6G43_RS01785 (I6G43_01785) comGF/cglF 365932..366393 (+) 462 WP_000531552.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6G43_RS01790 (I6G43_01790) comGG/cglG 366371..366796 (+) 426 WP_000265654.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6G43_RS01795 (I6G43_01795) - 366806..367396 (+) 591 WP_000679771.1 class I SAM-dependent methyltransferase -
  I6G43_RS01800 (I6G43_01800) comYH 367455..368408 (+) 954 WP_001008566.1 class I SAM-dependent methyltransferase Machinery gene
  I6G43_RS01805 (I6G43_01805) - 368458..369648 (+) 1191 WP_000167782.1 acetate kinase -
  I6G43_RS01810 (I6G43_01810) rnpA 369808..370179 (+) 372 WP_000748125.1 ribonuclease P protein component -
  I6G43_RS01815 (I6G43_01815) - 370154..370966 (+) 813 WP_000728102.1 YidC/Oxa1 family membrane protein insertase -
  I6G43_RS01820 (I6G43_01820) jag 370984..371973 (+) 990 WP_000242598.1 RNA-binding cell elongation regulator Jag/EloR -
  I6G43_RS01825 (I6G43_01825) - 372024..372647 (+) 624 WP_000969604.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35627.90 Da        Isoelectric Point: 4.3073

>NTDB_id=513197 I6G43_RS01800 WP_001008566.1 367455..368408(+) (comYH) [Streptococcus oralis strain FDAARGOS_886]
MNFEKIEQAYTYLLENVQVIQSDLVTNFYDALVEQNSIYLDGETKLEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVLVVEELFEQEEISILEMGSGMGILGATFLISLAKKVDYLGIEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAIASRYQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKRDKEIEPFVYPLTSLQDPAALMKFKENFQKWSKGTEM

Nucleotide


Download         Length: 954 bp        

>NTDB_id=513197 I6G43_RS01800 WP_001008566.1 367455..368408(+) (comYH) [Streptococcus oralis strain FDAARGOS_886]
ATGAATTTTGAAAAAATAGAACAAGCTTATACGTATTTATTAGAGAATGTCCAAGTCATCCAGAGTGATCTGGTGACCAA
CTTTTATGATGCCTTGGTAGAGCAAAATAGTATCTACCTGGATGGTGAGACCAAGCTAGAGCAGGTAAAGGAGAACAATC
AAGCTCTTAAACGCTTAGCGCTTCGCAAGGAAGAGTGGCTCAAGACCTATCAGTTTCTCTTGATGAAGGCAGGACAAACT
GAGCCTTTACAGGCCAATCACCAGTTTACGCCGGATGCCATTGCCCTCCTCTTGGTACTTGTTGTGGAAGAGTTGTTTGA
ACAAGAGGAAATTAGCATCCTCGAAATGGGTTCTGGAATGGGAATTCTGGGTGCTACTTTCTTGATATCTCTTGCTAAAA
AAGTAGATTACTTGGGAATTGAAGTGGATGACTTGCTGATTGATTTGGCGGCTAGTATGGCAGATGTGATTGGTTTGCAG
GCTGGTTTTGTTCAGGGTGATGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGATGTGGTCATTAGCGACTTGCCTGTCGG
CTATTACCCAGACGATGCCATCGCTTCACGCTATCAAGTGGCTTCTAGCCAAGAACATACCTATGCCCATCATTTGCTGA
TGGAGCAAGGTCTCAAGTATCTCAAGTCAGATGGCTATGCTATTTTTCTAGCTCCGAGCGACTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGGTTGGCTCAAAGACGAAGTGAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAAGAGACAAGGAAATAGAACCCTTTGTCTATCCTTTGACCA
GTCTGCAAGATCCAGCTGCATTAATGAAATTCAAAGAAAATTTTCAAAAATGGAGCAAAGGTACTGAAATGTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

57.556

98.107

0.565
  comYH Streptococcus mutans UA159

57.235

98.107

0.562