Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SPAF_RS09970 Genome accession   NC_017905
Coordinates   2091522..2092790 (-) Length   422 a.a.
NCBI ID   WP_041826499.1    Uniprot ID   -
Organism   Streptococcus parasanguinis FW213     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2086522..2097790
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPAF_RS09940 (Spaf_2026) - 2087903..2088208 (-) 306 WP_003001941.1 DUF1292 domain-containing protein -
  SPAF_RS09945 (Spaf_2027) ruvX 2088231..2088650 (-) 420 WP_003014525.1 Holliday junction resolvase RuvX -
  SPAF_RS09950 (Spaf_2028) - 2088650..2088916 (-) 267 WP_003002070.1 IreB family regulatory phosphoprotein -
  SPAF_RS09955 (Spaf_2029) - 2089040..2089636 (-) 597 WP_003014531.1 SP0191 family lipoprotein -
  SPAF_RS09960 (Spaf_2030) spx 2089771..2090169 (-) 399 WP_003009108.1 transcriptional regulator Spx -
  SPAF_RS09965 (Spaf_2031) recA 2090257..2091402 (-) 1146 WP_003014536.1 recombinase RecA Machinery gene
  SPAF_RS09970 (Spaf_2032) cinA 2091522..2092790 (-) 1269 WP_041826499.1 competence/damage-inducible protein A Machinery gene
  SPAF_RS09975 (Spaf_2033) - 2092888..2093442 (-) 555 WP_014714058.1 DNA-3-methyladenine glycosylase I -
  SPAF_RS09980 (Spaf_2034) ruvA 2093452..2094045 (-) 594 WP_014714059.1 Holliday junction branch migration protein RuvA -
  SPAF_RS09985 (Spaf_2035) mutL 2094066..2096009 (-) 1944 WP_041826500.1 DNA mismatch repair endonuclease MutL -
  SPAF_RS09990 (Spaf_2037) - 2096258..2096698 (+) 441 WP_003018046.1 LytTR family DNA-binding domain-containing protein -
  SPAF_RS09995 (Spaf_2038) - 2096692..2097147 (+) 456 WP_014714061.1 DUF3021 domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45178.34 Da        Isoelectric Point: 4.7395

>NTDB_id=51151 SPAF_RS09970 WP_041826499.1 2091522..2092790(-) (cinA) [Streptococcus parasanguinis FW213]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLFSTIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDPTALAKLDTFFASRPDYVRTPNNERQAQMIAGSIPLQNRTGLAVGGLIEVDDVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEEQSDPTVAPYAKTGEVTLRLSTKAKDQASADAKLDVLEKEI
LSRHTLDHQPLQELFYGYGDDNSMAKVAFDLLKRTGKTITAAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEGHPAGTVFIGLATPNGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=51151 SPAF_RS09970 WP_041826499.1 2091522..2092790(-) (cinA) [Streptococcus parasanguinis FW213]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTGAACACCAATGCTCAATTCTTGTCTGA
AAAATTGGCTAGTTTAGGAATTGATGTCTATTATCATGTGGCGGTAGGAGACAATGAAGGCCGTCTCTTCTCGACCATTG
AGACAGCTTCAAAACGCAGTGATTTGGTGATTTTATGCGGTGGACTTGGGCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGAAAGAACTGGTTTTTGATCCGACAGCGCTTGCTAAACTCGACACCTTCTTTGCCAGTCGCCC
TGATTATGTCCGGACGCCCAATAATGAGCGACAAGCACAAATGATTGCCGGATCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGATGATGTGACCTATGTCGTTCTACCTGGTCCGCCAAGTGAGTTAAAACCCATG
GTCAATGAACAATTGGTGCCTCATTTGACAACAGGGGAACAGCTCTTTTCAAGAGTCTTGCGCTTCTTTGGGATTGGGGA
AAGCCAGCTGGTTACGATCCTAGCAGATATCATTGAAGAGCAGAGTGATCCGACGGTTGCCCCTTATGCCAAGACGGGAG
AAGTAACCTTGCGTCTATCTACAAAGGCGAAGGATCAAGCTTCAGCGGATGCTAAGCTCGATGTCTTAGAAAAGGAAATC
TTATCACGTCACACGCTGGACCATCAACCCTTGCAAGAGTTGTTTTATGGTTATGGGGATGACAATTCGATGGCCAAGGT
TGCCTTTGATCTCTTGAAACGGACTGGTAAGACCATTACAGCTGCAGAAAGCCTGACGGCTGGCCTCTTTCAAGCGACTC
TGGCAGATTTTTCAGGAGCGTCCAGCATCTTCGCGGGTGGTTTTGTCACCTATAGTTTGGAAGAAAAAAGCAAGATGTTG
TCCATTCCAGCTCAAGAGTTGGAGCAACATGGAGTAGTGTCTCATTTTACAGCTCAAGCCATGGCTTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCCTAACCGGAGTTGCGGGGCCAGATAGTCTGGAAGGGCATCCAGCAGGGACCG
TCTTTATCGGACTTGCGACTCCAAATGGAGTGGATAGTGTCCAAGTCAATATCGCTGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTTCTTCATGCCTTTAATTTGGTACGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.58

98.815

0.737
  cinA Streptococcus mitis NCTC 12261

74.58

98.815

0.737
  cinA Streptococcus pneumoniae TIGR4

73.621

98.815

0.727
  cinA Streptococcus pneumoniae Rx1

73.621

98.815

0.727
  cinA Streptococcus pneumoniae R6

73.621

98.815

0.727
  cinA Streptococcus pneumoniae D39

73.381

98.815

0.725
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus suis isolate S10

55.448

97.867

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

47.47

98.341

0.467

Multiple sequence alignment